HAEMATOLOGICAL PROFILE IN DIABETICS IN INDIA , ADDING TO DISEASE MORBIDITY
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 9, Pages 2678-2693
Abstract
Background: Diabetics are burdened with glycemia and an decreased haemoglobin value also contributes, to increase the risk of development and also progression of micro vascular and macro vascular complications of diabetes.Objectives:
To study incidence of anaemia in diabetics with normal renal function, in comparison to non- diabetics who have normal renal function.
Design: An analytical cross sectional study comparing diabetics with normal renal function and non-diabetics with normal renal function.
Settings : It was conducted in hospitals attached to KMC Mangalore between September 2016 to July 2018. Group 1 - Diabetics as per ADA criteria. Group 2 - Non diabetics (RBS < 200).
Materials and Methods:
The estimated glomerlular filtration rate (eGFR) was calculated using Cockcroft-Gault Equation. Only those with eGFR>60 ml/min were included. Using the WHO criteria, the prevalence of anaemia was checked for. Duration of diabetes and prevalence of anaemia was correlated.
Sample Size: The sample size was 100. Both groups had 50 cases.
Results: In our study it was seen that 56 % of the diabetics were anaemic as compared to only 30 % of the non-diabetics. The p value was 0.0001. The odds ratio calculated showed that diabetics were 2.97 times more likely to have anaemia as compared to non-diabetics. Anaemic patients had an average of 9.68 years of diabetes. The non anaemic patients had an average of 6.32 years of diabetes. The p value was 0.038. The mean glycated haemoglobin amongst the anaemic patients was 7.2 and 6.9 amongst non anaemic patients. The p value was 0.450. The most common type of anaemia amongst diabetics was found to be normocytic normochromic anaemia. Amongst the non-diabetics microcytic hypochromic anaemia was the most common.
Conclusion: In our study it was seen that even in the absence of renal failure, the prevalence of anaemia was higher amongst diabetics as compared to non-diabetics. Longer duration and poorer control diabetes was also associated with a higher prevalence of anaemia.
Limitations:
Iron studies, Red cell indices were not done. Diabetic complications were not studied.Kidney size was not assessed by Ultrasound.
Conflicts of Interest:
It was a self-sponsored study.
Keywords:
- Article View: 223
- PDF Download: 243