CONTEMPORANEOUS EVIDENCE ON COVID-19 AND CARDIOVASCULAR DISEASE: A REVIEW
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 11, Pages 4873-4885
AbstractThe Coronavirus disease is caused by the SARS- CoV 2, which is one in 36 members of the coronavirus family. This virus has a big RNA genomic feature and positively sensitive to RNA. This virus has the speciality to survive in the environment for 3-4 days. The similar viral infection has developed in the year 2002-2003 as Severe Acute Respiratory Syndrome (SARS) and during 2012 as Middle East Respiratory Syndrome (MERS). The individuals with comorbidities and old age are more prone to infect and can worsen the condition. This group of people are increasing the mortality and morbidity burden of the disease. The coronavirus usually attacks the Angiotensin-Converting Enzyme 2 (ACE 2) cell receptors and the inactivation of these cells are the key point of the respiratory failure among the cases. The COVID 19 affect the cardiovascular system by the two mechanisms; cytokine storm and the effect of the virus on the heart. These causes may lead to myocardial injury, heart failure and cardiac arrhythmias. While considering the cardiac transplantation a careful selection of the donor is very important. Till now there were no cases reported like transmission of corona infection from the donor to the recipient but there is a chance. The exact treatment protocol or vaccine not yet developed. But the azithromycin and hydroxychloroquine drug combination showing a reduction in the viral load among the infected cases. The preventive measures are very important and crucial in the elimination of this viral infection from our world.
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