European Journal of Molecular & Clinical Medicine

Abstract

Purpose: This systematic review and meta-analysis was done to highlight the existing
literature and organize data associating the mortality of coronavirus disease 2019
(COVID-19) in patients with and without asthma.
Search criteria: The Scopus, Embase, PubMed, medRxiv. org and Google Scholar
databases were explored for studies associating the clinical results of with and without
asthmatic patients diagnosed with COVID-19. Mortality data were concise with the
Mantel-Haenszel OR with 95% CI in a random-effects model. Five retrospective studies
met the inclusion criteria. A meta-analysis of data from 1181 asthmatic patients and
8,847 nonasthmatic patients specified that the presence of asthma had no substantial
consequence on mortality (OR = 0.96; 95% CI 0.70–1.30; I2 = 0%; p = 0.79).
Result: Results were stable in a sensitivity analysis. A descriptive analysis of other
clinical outcomes designated no alteration in the duration of hospitalization and the risk
of intensive care unit (ICU) transfer between asthmatic and nonasthmatic patients.
Conclusion: Asthma may not upsurge the mortality of COVID-19.