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  2. Volume 7, Issue 11
  3. Author

Online ISSN: 2515-8260

Volume7, Issue11

Toxicological Effects of Paraphenylene-diamine On Skin Of Albino Rats-An In-vivo Study

    Shomalla J, Ashfaq ul Hassan, Nusrat J, Sangeeta G

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 5163-5167

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Abstract

Materials and methods: This study was undertaken on 24 albino rats,  in the department of anatomy in Govt. Medical College Jammu. These rats were divided into four groups of 6 rats each.   Group A, Group B, Group C rats were painted with 1mg/kg body wt, 2mg/kg body wt and 3 mg/kg body wt of paraphenylene-diamine respectively while Group D rats were painted with distilled water after shaving their backs.
Results: There were gross and histological changes in the liver and skin of the albino rats by the repeated topical application of paraphenylene-diamine on the albino rats.
Conclusion: Repeated topical  application of paraphenylene-diamine results in systemic absorption of the dye and consequent damage of the internal organs. 
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(2021). Toxicological Effects of Paraphenylene-diamine On Skin Of Albino Rats-An In-vivo Study. European Journal of Molecular & Clinical Medicine, 7(11), 5163-5167.
Shomalla J, Ashfaq ul Hassan, Nusrat J, Sangeeta G. "Toxicological Effects of Paraphenylene-diamine On Skin Of Albino Rats-An In-vivo Study". European Journal of Molecular & Clinical Medicine, 7, 11, 2021, 5163-5167.
(2021). 'Toxicological Effects of Paraphenylene-diamine On Skin Of Albino Rats-An In-vivo Study', European Journal of Molecular & Clinical Medicine, 7(11), pp. 5163-5167.
Toxicological Effects of Paraphenylene-diamine On Skin Of Albino Rats-An In-vivo Study. European Journal of Molecular & Clinical Medicine, 2021; 7(11): 5163-5167.
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