• Register
  • Login

European Journal of Molecular & Clinical Medicine

  • Home
  • Browse
    • Current Issue
    • By Issue
    • By Subject
    • Keyword Index
    • Author Index
    • Indexing Databases XML
  • Journal Info
    • About Journal
    • Aims and Scope
    • Editorial Board
    • Publication Ethics
    • Indexing and Abstracting
    • Peer Review Process
    • News
  • Guide for Authors
  • Submit Manuscript
  • Contact Us
Advanced Search

Notice

As part of Open Journals’ initiatives, we create website for scholarly open access journals. If you are responsible for this journal and would like to know more about how to use the editorial system, please visit our website at https://ejournalplus.com or
send us an email to info@ejournalplus.com

We will contact you soon

  1. Home
  2. Volume 7, Issue 11
  3. Authors

Online ISSN: 2515-8260

Volume7, Issue11

In-Vitro Screening of Reverse Transcriptase Activity of Selected Indian Medicinal Plants against Human Immunodeficiency Virus Type-1

    Priyadarshini K Kulandhaivel M Sankareswaran M Anbalagan S

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 11, Pages 5168-5175

  • Show Article
  • Download
  • Cite
  • Statistics
  • Share

Abstract

Human Immunodeficiency Virus type-1 (HIV-1) is that the explanation for Acquired Immune Deficiency Syndrome (AIDS), a serious human viral disease.The high cost of the HAART regimen has impeded its delivery to over 90% of the HIV/AIDS population within the world. The aim of the present study was to evaluate the in vitro anti-HIV activity of selected Indian medicinal plant extracts.Extracts were prepared from dried plant Vitex negundo, Evolvulusalsinoides and Datura metel leaf with Hexane, Methanol, Ethanol, Chloroform, and Petroleum ether. The phytochemical activities and HIV-1 RT inhibition activity (HIV-1 RT colorimetric ELISA kit –Roche Kit method) was carried with the all solvent extracts of Vitex negundo, Evolvulusalsinoides and Datura metelwas determined. The methanolic extracts of Vitex negundo have given the maximum and positive result with 74.76±1.36, which proves that Vitex negundo has a potential antiviral activity against HIV. Phytochemical analysis conducted on the plant extracts revealed the presence of constituents which are known to exhibit medicinal also as physiological activities.The predominant components present altogether the extracts of Vitex negundo are flavonoids, Terpenoids and steroids. Thus this study seems to justify the normal use of plant for the treatment of communicable disease of viral origin.
Keywords:
    HIV Vitex negundo Evolvulusalsinoidesand Datura metelHIV-1 RT Phytochemical analysis
  • PDF (296 K)
  • XML
(2021). In-Vitro Screening of Reverse Transcriptase Activity of Selected Indian Medicinal Plants against Human Immunodeficiency Virus Type-1. European Journal of Molecular & Clinical Medicine, 7(11), 5168-5175.
Priyadarshini K; Kulandhaivel M; Sankareswaran M; Anbalagan S. "In-Vitro Screening of Reverse Transcriptase Activity of Selected Indian Medicinal Plants against Human Immunodeficiency Virus Type-1". European Journal of Molecular & Clinical Medicine, 7, 11, 2021, 5168-5175.
(2021). 'In-Vitro Screening of Reverse Transcriptase Activity of Selected Indian Medicinal Plants against Human Immunodeficiency Virus Type-1', European Journal of Molecular & Clinical Medicine, 7(11), pp. 5168-5175.
In-Vitro Screening of Reverse Transcriptase Activity of Selected Indian Medicinal Plants against Human Immunodeficiency Virus Type-1. European Journal of Molecular & Clinical Medicine, 2021; 7(11): 5168-5175.
  • RIS
  • EndNote
  • BibTeX
  • APA
  • MLA
  • Harvard
  • Vancouver
  • Article View: 178
  • PDF Download: 220
  • LinkedIn
  • Twitter
  • Facebook
  • Google
  • Telegram
Journal Information

Publisher:

Email:  editor.ejmcm21@gmail.com

  • Home
  • Glossary
  • News
  • Aims and Scope
  • Privacy Policy
  • Sitemap

 

For Special Issue Proposal : editor.ejmcm21@gmail.com

This journal is licensed under a Creative Commons Attribution 4.0 International (CC-BY 4.0)

Powered by eJournalPlus