Assessment of risk factors for diabetic nephropathy among newly diagnosed Type 2 diabetic subjects: A pilot study
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 11, Pages 5543-5547
AbstractBackground: The prevalence of diabetes mellitus (DM) is expanding all through the world and this burden of disease is generally contributed by the expanding cases of type 2 DM (T2DM). DM is the main cause of chronic kidney disease (CKD) in developed nations and is quickly turning into the main cause for CKD in developing countries. Material & Methods: The present case-control study was conducted at department of Department of Medicine of our tertiary care hospital. The study duration was of one year. Patients were enrolled from outdoor and from ward by simple random sampling. Recently diagnosed (<3 months), adults ( >18 years), T2DM patients were enrolled in the present study. Results The age of study participants was ranged from 34 years to 76 years. The mean age of cases was 48.4 ± 2.9 years and mean age of controls was 44.4 ± 2.1 years. Out of total study participants it was reported that males 54% were likely affected more than females 46% in cases while among controls 48% were males and 52% were females. The mean BMI of cases was 26.6 ± 3.47 and mean BMI of controls was 24.6 ± 2.41. Family history of diabetes mellitus was present in all 30 cases whereas it was present in 20 controls. Family history of diabetic nephropathy was found in 16 patients and 4 controls. Mean fasting blood glucose (mmol/L) was 9.90±1.89 mmol/L among cases and among controls mean fasting blood glucose (mmol/L) was 8.43±3.28 mmol/L. Mean blood glucose after 2 hours (mmol/L) was 15.11±2.52 among cases and among controls mean blood glucose after 2 hours (mmol/L) was 12.61±4.72 mmol/L. Mean HbA1c (%) was 8.18±1.11among cases and among controls mean HbA1c (%) was 6.95±1.44.Conclusion: In the present study, hypertension was present as risk factor among 22 cases and among 22 controls. Dyslipidemia was present as risk factor among 24 cases and among 9 controls. Smoking was present as risk factor among 11 cases and among 8 controls.
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