European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Prolactin (PRL) is a pituitary hormone essential for various physiological functions in the human body. Patients with increased serum PRL concentrations are associated with an adverse cardiovascular risk profile, typically characterized by insulin resistance, lowgrade inflammation, and impaired endothelial function.
Aim: To compare the serum prolactin between diabetic population with and without acute
coronary syndrome and healthy controls.
Materials and methods: In our analytical cross-sectional study, after obtaining informed consent we assessed serum prolactin of 3 groups; type 2 diabetes mellitus patients with acutecoronary syndrome (ACS) (n=50), type 2 diabetes mellitus patients without acute coronary syndrome (n=50), and healthy control (n=50). Continuous variables were compared by one-way ANOVA, P value < 0.05 was considered statistically significant. IBM SPSS version 22 was used for statistical analysis.