European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Catheter-related bloodstream infection (CRBSI) is a critical problem in dialysis
center.
Aim: To study the prevalence of central venous catheter related blood stream infections and to
identify the microbiological profile of organisms causing CRBSI.
Materials and Methods: This prospective observational study carried out at Dialysis unit over
a period of two years on 145 hemodialysis patients, who had cultures of catheter and blood
samples were studied.
Results: A total of 557 haemodialysis catheters (tunnelled and non-tunnelled) were
inserted during the study period, and among them, CRBSIs was seen in 145 cases.Mean
duration of dialysis catheters in situ was 20.6days.99 (68.2%) patients were males, and 46
(31.7%) were females. Diabetes mellitus (76.5 %) was the most common premorbid illness
associated with CRBSI. 81.3% patients found to be below 10 mg/dl of Hb, and
68.3%patients had leucocytosis. Among 145 of CRBSI, blood cultures were positive in 48
patients, and 97 patients were culture negative.45.8% isolates were gram-positive and
52.8% isolates were gram-negative bacteria, and one isolate was found to be fungal
infection.Among gram positive, CONS were most isolated, followed by Enterococcus,
MSSA and MRSA.