European Journal of Molecular & Clinical Medicine

Abstract

The present study was designed to assess the altered behavioural activity of Wistar rats exposed to five different noise intensities. Wistar rat was divided into five groups such as EG1, EG2, EG3, EG4, and EG5 and in respect to that 60, 80, 100, 120, and 140 dB noise exposure (1hr/day) was assigned for 30 days, and post noise effects of noise stress were also evaluated on 7th and 14th day by employed Actophotometer and Elevated Plus Maze respectively. The experimental rats of all the groups showed a significant (p<0.05) reduction in locomotor activity and increased anxiety level after 1st day of noise exposure of different noise intensities, but animals of group EG1 and EG2 also showed an adaptive response towards their respective noise intensities on 15th, 30th and post noise day i.e. 7th and 14th day, while a consistent reduction in locomotion and increased anxiety level were observed in EG3, EG4 and EG5 groups on animals on noise stressed exposure and post noise days respectively. The present study results suggested that noise stress can alter behavioural activity and may potentiate the risk of neurodegenerative disorders.