Comparison of B lymphocyte effects of laparoscopic versus open prostatectomy in prostate cancer patients.
European Journal of Molecular & Clinical Medicine,
2021, Volume 8, Issue 3, Pages 437-441
AbstractThe preoperative B-cell counts (CD 19+) appeared to be more reduced by laparoscopic prostatectomy when compared with open surgery. These findings are important because accumulating evidence suggest that the B-cell subsets emerged in response to prostate cancer exhibit association with unfavorable prognosis. High per cent of B- cells infiltrating tumor were shown to be associated with more aggressive disease. The B-cell depleting therapies used with different prostatectomy settings should be closely monitored to make timely adjustments to peripheral CD19+ counts
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