European Journal of Molecular & Clinical Medicine

Abstract

Introduction: Osteomyelitis is pathologically defined as inflammation of bone and bone marrow due to infection with a microbial pathogen. Septic arthritis is pyogenic infection of the joint either due to direct extension from local tissue infection or more commonly as a result of bacteremia. Microbiological diagnosis in these cases can be made by culture on enriched media and PCR. As PCR detects bacterial DNA, it does not rely on the presence of viable bacteria in the sample for identification. The rapidity of PCR along with its higher sensitivity and specificity enables faster and more accurate diagnosis and treatment