Ocular Manifestations in Sickle Cell Patients at a Tertiary Care Set up of Western Odisha: Cross Sectional Study
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 10, Pages 3668-3673
AbstractIntroduction: Sickle cell disease (SCD) is the most common genetic disease worldwide. SCD can affect virtually every vascular bed in the eye and can cause blindness in the advanced stages. Objectives: To determine the prevalence and patterns of ocular manifestations in patients of sickle cell disease attending VIMSAR, Burla and to correlate these manifestations with haematological parameters. Methods: The study was conducted among 51 subjects in four months duration. The sickle cell patients with disease duration of more than 10 years and indoor patients admitted for sickle cell crisis in General Medicine and Pediatrics ward were included in the study. Hematologic investigations were done and ophthalmic investigations such as visual acuity, silt lamp bio-microscopy and fundoscopy was done and compared. Results: The study depicts that out of 51 study subjects, prevalence of positive Proliferative Sickle Cell Retinopathy (PSR) in the study population was 13.72%. The hematocrit values were lower in positive PSR cases and higher in negative PSR cases. These difference in values were statistically significant (p <0.05).Conclusion: Sickle cell retinopathy is a significant health problem, hence routine awareness campaign should be organized in sickle cell institute regarding the need of early interventions which could protect them from dreadful complications.
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