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Determination of cardiovascular autonomic neuropathy in type II DM patients

    Authors

    • Amit Varshney 1
    • Vidya Sagar Ram 2
    • Kanhaiya Prasad 1

    1 Associate Professor, Department of General Medicine, United Institute of Medical Sciences and Hospital, Prayagraj, U.P., India

    2 Associate Professor, Department of General Medicine, U P University of Medical Sciences, Saifai, U.P., India;

,

Document Type : Research Article

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Abstract

Background: The diabetic neuropathy, including the cardiovascular autonomic neuropathy
(CAN), is a common complication of type 1 and 2 diabetes that leads to high mortality and
morbidity. The present study was conducted to determine CAN in type II DM patients.
Materials & Methods: 168 type II DM patients of both genders were recruited. Resting
heart rate, blood pressure, and body mass index (BMI), systolic blood pressure (SBP) ≥140
mmHg or diastolic blood pressure (DBP) ≥90 mmHg, fasting lipid profile (low-density
lipoprotein/LDL, high-density lipoprotein/HDL, triglycerides/TG) and cardiac autonomic
function was evaluated with the CAN system analyzer as early, definite and advanced
CAN.
Results: CAN was seen in 66 patients. The mean age (years) was 45.2 and 44.5, duration of
diabetes (years) was 6.1 and 12.3, SBP (mm Hg) was 130.4 and 134.5, DBP (mm Hg) was
86.2 and 87.6, resting heart rate (beats/min) was 76.3 and 87.4, LDL (mg/dl) was 102.4 and
98.6, HDL (mg/dl) was 40.5 and 38.1 and TG (mg/dl) was 165.2 and 184.6 in CAN- and
CAN+ patients. The difference was non- significant (P> 0.05). Severity of CAN found to be
early in 20%, definitive in 45% and advanced in 35%. The difference was significant (P<
0.05).
Conclusion: Type II diabetes patients had high prevalence of cardiac autonomic
neuropathy.

Keywords

  • Cardiac autonomic neuropathy
  • Diabetes
  • Lipid Profile
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European Journal of Molecular & Clinical Medicine
Volume 7, Issue 10
December 2020
Page 3788-3792
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APA

Varshney, A., Ram, V. S., & Prasad, K. (2021). Determination of cardiovascular autonomic neuropathy in type II DM patients. European Journal of Molecular & Clinical Medicine, 7(10), 3788-3792.

MLA

Amit Varshney; Vidya Sagar Ram; Kanhaiya Prasad. "Determination of cardiovascular autonomic neuropathy in type II DM patients". European Journal of Molecular & Clinical Medicine, 7, 10, 2021, 3788-3792.

HARVARD

Varshney, A., Ram, V. S., Prasad, K. (2021). 'Determination of cardiovascular autonomic neuropathy in type II DM patients', European Journal of Molecular & Clinical Medicine, 7(10), pp. 3788-3792.

VANCOUVER

Varshney, A., Ram, V. S., Prasad, K. Determination of cardiovascular autonomic neuropathy in type II DM patients. European Journal of Molecular & Clinical Medicine, 2021; 7(10): 3788-3792.

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