European Journal of Molecular & Clinical Medicine

Abstract

Background: Fistula-in-ano (FIA) is one of the most common benign anal conditions in daily surgical practice. Modern management of anal fistula include anal fistula plug, fistula laser closure, adipose-derived stem cells and platelet-rich plasma (PRP )injection. The study was aimed to compare the efficacy of platelet rich plasma injection versus ligating inter-sphincteric fistulous tract in treatment of high transsphincteric peri-anal fistula. Patients and methods: Our study was carried out in General Surgery Department, Zagazig University Hospitals and included 18 patients who were divided in two groups; 9 patients were treated with platelet rich plasma injection after curretage of the fistulous tract and 9 patients were treated with ligation of the intersphincteric fistulous tract with close monitoring and followed up of all the patients of both groups as regards to: operation time, hospital stay, healing time, postoperative incontinence and recurrence.