EVALUATION OF CARDIOVASCULAR ABNORMALITIES AMONG COPD PATIENTS
European Journal of Molecular & Clinical Medicine,
2020, Volume 7, Issue 11, Pages 7406-7417
Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent and progressive airflow limitation and is associated with enhanced chronic inflammatory response. Exacerbations and comorbidities contribute to the overall severity in individual patients.The present study was carried out to assess the severity of right heart disease using 2-D transthoracic echocardiography and compare the findings with BODE index among COPD patients.
This cross-sectional study was carried out among 50 patients diagnosed with COPD as per GOLD criteria in the outpatient clinic. Patients with known history of cardiovascular complications were excluded. A 2-dimensional echocardiography was performed to document the cardiovascular changes. The findings were compared with BODE index.
Majority of the patients were aged between 61-80 years (52%) and were males (90%).Based on the BODE index classification, majority of the participants belonged to BODE index >5(54%). Based on the echocardiography findings, 46% of the participants had severe cardiovascular complications. It was observed that FEV1 was significantly lower in the participants with BODE index >5 and among those with severe echo findings.
This study infers that the although severity of airflow limitation, dyspnoea scaling and 6MWD are independent risk factors for right heart dysfunction, the integrated index of these factors along with the BODE index is a more sensitive predictor of the severity of right heart dysfunction in stable COPD patients.
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