European Journal of Molecular & Clinical Medicine

Indian Mythology is one of the unique elements of Indian culture which enriches it further and makes it a unique one in the world. Through generations, different stories in Indian Mythology have been passed from generations to generation orally or in written scriptures. Gender dichotomy has been reflected as a dominant part of patriarchal society in these mythologies. As a result, this factor creates dangerous consequences which limit a person's full potential and wellbeing. Male or female because of these fixed identities imposed by the society, are forced to ignore their personality traits, temperament and unique characteristics and have to follow the fixed social and cultural notions of 'Masculinity' and 'Femininity’. This paper attempts to read Chitra Banerjee Divakaruni’s novel The Palace of Illusions as an attempt to reinterpret the gender and psychological issues which testifies unawareness of a double marginality, an inequality felt by Draupadi both in terms of gender and psyche. It redefines the roles and parameters of women as a challenge of womanhood, the embodied form of action, knowledge, devotion and power. The inner thoughts and resentments of Draupadi in various stages of her life are given voice by the novelist. Different from the epic, this Draupadi has been presented as one who questions the terms of the mythology which records her existence, by bringing out what it represses or excludes. Her life has been described in her own way which radically questions and consistently undermines the previous constructions of her life, being a victim of patriarchy which is perpetuated by the dominant discourses of the time, examining the power relation of Indian culture where gender is the basis of determining the role in society.

The stress problems of CAPFs personnel due to family and domestic issues require an effective but practical solution. The objective of this paper is to analyse the issues on provision of family accommodation at BOPs/PLACE OF DUTY for the stress management of CAPFs personnel while performing the operational duties in guarding the nation. The absence of humane approach and concern on this issue caused a severe gap in the well-being of our forces, causing distress and prone to extreme steps. The solution of such a diverse and complex problem cannot be a universal or sacrosanct. A comprehensive humane approach and policy is needed in this regard which can only be derived after we understand the dynamics and the nature of the job. The research also revolves around the suggestions that can be taken by the Govt. to provide better life to CAPF personnel.

Objectives: This paper points to verify the influences of motherly exposure the basic air depressions off infant mortality. For further investigation of these relationships, we used vital registry data to retroactively build (2907) deaths occurred between 2009 and 2013 at Children's Medical City Hospital for children younger than one year and (1167) of them less than a month Previous investigates have concerned air contamination in raised mortality and disease, mainly in the aged populace and childish person. Extra in recent times, relations with death in newborns then through several generative reproductive effects have also been registered
The purpose from such study is to analysis the relationship relating revealing to open-air pollution for the period of gestation then infant mortality, airborne contamination is linked to poor pregnancy.
Elevation indication has exposed that population’s physical and mental health be able to be influenced air study by several contaminations.
Then, this investigate
Purposes to examine the correlate between air pollutions (O3, SO2, NO2, CO, Pb, PM2.5 or PM10) and Born prematurely. For the interval period (2009-2013).
Method: Totally Infant mortality information besides child birth information since (first January 2009 to end December 2013) be there recorded Children’s Hospital in Medical City in Baghdad Iraq
And Daily data on air quality from The Iraqi Ministry of Health and the Environment, The reality of the environment report (2010 ...) report on the status of the status of the Iraqi Environment

The present study included species composition of fish and some ecological factors in haji Ali drainage in the Babylon province. Three stations were chosen for the purpose of the study, the station of first is placed at the beginning of the drain(St1), the second in the middle(St2) and the third at the end(St3), monthly samples were selected from June 2019 to May 2020. Water temperature showed slight changes to the stations were recorded between(11.8C°-28.9C°).Salinity ranged between 0.12gm/l -2.55 gm/l. pH values tended in some months of study to the acidic side and in other months to the basic side has recorded from (6.4-9.3). Dissolved oxygen values ranged from (1.71-
8 .86)mg/l.Biological oxygen demand values ranged between (0.04-4.59) mg/l.Throughout the period mentioned above, a total of 5 397 fish were obtained, belonging to 14 species and 7 families, 11 species of them were native species whereas 3 of them were alien species. The most abundant species was Carassius auratus constituted 31.28% of the total caught of the first station, the value of the dominance index (D3) in first station was 78.53%. The most abundant species in second station was C. auratus constituted 31.46% of the total caught, the value of the dominance index (D3) in the second station was 70.03%. The most abundant species in third station was Planiliza abu constituted 28.08% of the total caught, the index of dominance value (D3) in the third station was 75.68%. Richness index (D) was ranged between (0.66-1.92) and diversity index (H) recorded (1.07-2.01),while evenness index (J) ranged (0.55-0.70).

The coronavirus disease is already at an alarming level because it spreads to 34 provinces in Indonesia, and the mortality rate has reached 7-8%, which is far above the global average. Nevertheless, the government has worked hard to reduce the spread through various policies, including the closure of schools and offices, encouraging people to stay at home, and implementing the Large-Scale Social Restrictions (PSBB). The policy has an impact on people's behavior. Therefore, an online survey was conducted to describe it. This survey was carried out from 5-10 May 2020, with 556 respondents of at least 17 years old, and it extended to various regions in almost all the provinces. Because it was online, the survey had limitations that could not represent the entire population. During the pandemic, various behaviors emerged in the community. Some people behaved as usual, while others acted like experts. Fifteen behaviors were studied, including COVID-19 knowledge, activities during the pandemic, anxiety levels, people's perception, and habit changes during the pandemic.

Data from Indonesia Demographic and Health Survey (IDHS) 2017 show the increase on the knowledge of prevention for HIV/AIDS among Women (49%) and married Men (55%). However, the factors that influence the increase of knowledge in the community, especially among eligible women (EW) are still unknown. On the other side, to increase the number of HIV voluntary counselling and testing (VCT) requires a good knowledge from community, so it is important to identify what factors that are related to HIV/AIDS knowledge. Therefore, this study aims to determine the factors associated with HIV/AIDS knowledge among EW.
This is a cross-sectional study using secondary data from IDHS 2017 (data couples record). Data were analysed using the Structural Equation Modelling (SEM). This study analyses the relationship between predisposing, enabling and reinforcing factors with the HIV/AIDS knowledge of EW.
The results show that more than 75% of 8.838 EW had less knowledge about HIV/AIDS. There are 73.1% of respondents who have mobile phones, but only 4.9% of respondent access information about HIV / AIDS via the internet. In addition, there are 32.2% of respondents who have an elementary school education level or have no education attainment. From the results of PLS-SEM analysis, it is known that the education level and wealth index of EW are predisposing factors that influence EW’s HIV/AIDS knowledge (p-value = 0,000). The frequency of reading the newspaper and the possession of mobile phone are the enabling factors that influence EW’s HIV/AIDS knowledge (p-value = 0.025). Meanwhile, the factors of health workers and community meetings are the reinforcing factors related to EW’s HIV/AIDS. Therefore, health promotion is needed to increase the number of women in continuing education, completing secondary education to higher education, and the innovation to use information technology to disseminate information about women's reproductive health to the community.

Background:Gestational diabetes mellitus (GDM) becomes common cases over the globe. GDM prevalence is counted as 1-3% out of all pregnancies in the west and 90% of them are complicated by diabetes. GDM is related with the increasing of maternal risk and short-time or long-term perinatal complication.GDM incidents in Indonesia are identified around 1,9-3,6% and around 40-60% women, who ever experienced with GDM, on the further observation after labouring will have diabtes melitus or glucose tolerance disorder. This research is aimed to identify the mother’s experience in GDM self-management.
Methods: This research is a qualitative research with phenomenology approach. This research was conducted on October 2018 – June 2019. The data were collected by employing interview that supported by documentation study over 8 mothers who had GDM interview and 3 midwives in charge at the KIA poly service. The data were analyzed by using thematic analysis.
Results: Qualitative analysis resulted five themes that cover nutrition management, education, glucose monitoring, sports and medication. The results showed that pregnancy mother tried to control the eating pattern as suggested by the health-workers. The mothers should conduct routine glucose controlling, perform physical activity, such as regular walk, perform house works or pregnancy workout. The appropriate medication during the pregnancy involves insulin.
Conclusion: This research reveals mothers’ experiences in GDM self-management in terms of lifestyle. The result of the research could be a valuable guidance in developing comprehensive self-management service, by considering more on mother’s self-management. The necessities of more effective GDM counceling is required to ensure clear understanding about principal self-management for pregnant mothers, hence it could help mother in enhancing adaptation and ability in dealing with GDM. Besides, it could increase the alert towards the risks on pregnancy with diabetes mellitus. Hence screening examination on diabetes melitus.
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GDM is related with the increasing of maternal risk asing of maternal risk asing of maternal risk asing of maternal risk asing of maternal risk asing of maternal risk asing of maternal risk asing of maternal risk asing of maternal risk asing of maternal risk and and short short -time or long time or longtime or longtime or longtime or long time or longtime or long time or long-term perinatal complication perinatal complication perinatal complicationperinatal complicationperinatal complication perinatal complicationperinatal complicationperinatal complicationperinatal complication perinatal complication .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia .GDM incidents in Indonesia are are are identified around 1,9 identified around 1,9 identified around 1,9 identified around 1,9 identified around 1,9identified around 1,9 identified around 1,9 -3,6% 3,6% and around 40 and around 40 and around 40 and around 40 and around 40and around 40 and around 40 -60% 60% 60% women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with women, who ever experienced with GDM, GDM, on the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melituson the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melitus on the further observation after labouring will have diabtes melitus or glucose tolerance or glucose tolerance or glucose tolerance or glucose tolerance or glucose tolerance or glucose tolerance or glucose tolerance or glucose tolerance or glucose tolerance or glucose tolerance or glucose tolerance disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self disorder. This research is aimed to identify the mother’s experience in GDM self -management.management.management.management. management.management.management.management.Methods: Methods: This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This research is a qualitative with phenomenology approach. This This This research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 research was conducted on October 2018 – June 2019. June 2019. June 2019. June 2019. June 2019. The da The da ta were collected ta were collected ta were collected ta were collected ta were collected ta were collected ta were collected ta were collected ta were collected ta were collected ta were collected ta were collected by by employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM employing interview that supported by documentation study over 8 mothers who had GDM interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by interview and 3 midwives in charge at the KIA poly service. The data were analyzed by using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis. using thematic analysis.Results:Results:Results: Results: Results: Qualitative analysis resulted Qualitative analysis resultedQualitative analysis resultedQualitative analysis resulted Qualitative analysis resultedQualitative analysis resultedQualitative analysis resultedQualitative analysis resulted Qualitative analysis resulted Qualitative analysis resultedQualitative analysis resultedQualitative analysis resulted Qualitative analysis resulted Qualitative analysis resultedQualitative analysis resulted five themes five themesfive themesfive themes five themesfive themesfive themesfive themes that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, that cover nutrition management, education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. The results showed that pregnancy education, glucose monitoring, sports and medication. 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The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers workers. The mothers should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose should conduct routine glucose controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular controlling, perform physical activity, such as regular walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the walk, perform house works or pregnancy workout. The appropriate medication during the pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin. pregnancy involves insulin.Conclusion:Conclusion: Conclusion:Conclusion: Conclusion: Conclusion:Conclusion: This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self This research reveals mothers’ experiences in GDM self -management in termmanagement in term management in term management in termmanagement in termmanagement in termmanagement in term management in termmanagement in term s of lifestyle. of lifestyle. of lifestyle. of lifestyle. of lifestyle. of lifestyle. The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the research could be a valuable guidance in developing The result of the 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considering more on mother’s self -management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear management. The necessities of more effective GDM counceling is required to ensure clear underunderunder understanding about principal self standing about principal selfstanding about principal selfstanding about principal self standing about principal self standing about principal self standing about principal self standing about principal self standing about principal selfstanding about principal selfstanding about principal self standing about principal selfstanding about principal self standing about principal self -management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help management for pregnant mothers, hence it could help mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDMmother in enhancing adaptation and ability dealing with GDM mother in enhancing adaptation and ability dealing with GDM. 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The purpose of this study was to evaluate the total daily sitting time for male and female undergraduate students and to compare their daily sitting time between weekdays and weekends. A sample of 375 participants responded to the Sedentary Behaviour Questionnaires (SBQ) survey. T-test was used to analyse the differences in sitting time between genders, while multivariate analysis of variance (MANOVA) was performed to investigate the gender differences in the sitting time between weekdays and weekends. The results showed that female undergraduate have a longer daily sitting time (M=9.64 hours/day, SD=30.302) as compared to the male undergraduate (M=9.46 hours/day, SD=31.296). However, there was no significant difference reported between sitting time for both genders (t=1.379, p= 0.169, p>0.05). Higher total sitting time on weekdays and weekends were also reported by female undergraduate students as compared the male undergraduate students. Similarly, no significant findings were also reported between genders during weekdays and weekends. The reported F-value was F(2,375)=1.7, P=0.05: Wikls’ Lambda=.99; partial eta squared=0.007. Prolong durations of daily sitting time (more then 6 hours daily) is associated with higher rate of chronic diseases and premature death especially among working adults. Hence, undergraduates who are future workforce replacements need to be encouraged to be active and not sit too long during their study years. Good habits such as completing their tasks while standing and to break the prolonged sitting patterns with slight movements should be inculated in their daily routines. This can help them to reduce the risk of being sedentary by sitting too much and too long in a day.

Community-based tourism is not only a tourism industry that aims to bring maximum profits to investors. Instead, it pays more attention to the impact of tourism on communities and environmental resources. Agrotourism has become an inevitable trend worldwide and is regarded as a potential gold mine for the development of tourism in southern Vietnam. Sơn Islet has initially been the residence of a few gardening and cage fish farming families. Until recently, the residents of the small island began to develop one of the earliest and most popular community-based agrotourism models in Cần Thơ City. As an emerging type of tourism that has recently grown in Vietnam, agrotourism has not yet considered much by researchers, and there are few studies on agrotourism, or only economic impact has been mentioned. This article aims to learn more about the overall effect of agrotourism on local communities in order to have some recommendations on making community-based agrotourism more effective. Qualitative research with observations and 22 in-depth interviews have been conducted to collect research data. This article discusses both the positive and negative effects of agrotourism on local communities. The elements of success have also been observed, and some suggestions have been made to develop agrotourism, maintain the success of this community model based on agrotourism on Sơn Islet, and achieve breakthrough growth in the near future.

Profitability and competitiveness cannot be gained without the proper utilization of workforce. Modern day organizations are experiencing difficulties to retain and engage their competent employee. The intention to quit or turnover intention of the employee has been a prime area of concern for the banks as the labour market exhibited a shortage of workforce that is competent as well as qualified. Banks witnessed a growing phase with intense competition from newly entered private and foreign banks. In this scenario employees may switch their jobs in the wake of better compensation and growth opportunities offered. Therefore, there is a need to study new and improved management concepts like workplace spirituality (WPS) to improve the workplace and make the employees more committed. This study explores the relationship of WPS on employee’s behavioral outcomes like turnover intention in Pakistani banking sector. The mediation of psychological contract in this relationship is also the focus of this research. Top five banks have been chosen for the study. The selection of top five banks was based on the number of employees. The main focus of this research is to find out that how the concept of workplace spirituality can help the baking sector to lower down the turnover intention of their employees by fulfillment of the psychological contract in the context of Pakistani banking sector. Data were analyzed by using PLS-SEM as used by past researchers like Chin (2012). Sample size was 338 and questionnaire distribution was done in different branches of top five banks of Pakistan for the purpose of data gathering. Simple random sampling was used for distribution of questionnaire. Overall results show the positive linkage of WPS and psychological contract on the employee’s turnover intention of banking employees. This research endeavor is an attempt to provide the useful insight into the concept of WPS, psychological contract and employees turnover intentions.

Career management is a very important, sensitive and a key factor for both employer and employee. Because both want to grow, develop and successful in present and future as well. Along with career management turnover intention is also a point of concern for employer and employees. Turnover intention is increasing day by day in top talented employees and in organizations as well. Both the factors career management and turnover intention are always keep in the consideration of the researchers. The present study was aimed at understanding the concept of individual career management and organizational career management in the context of Malaysian banking sector. Literature supports the concept that individual career management and organizational career management are interlinked concepts and it has the linkage with the turnover intention as well. Banking sector the world over is facing the issue of employee turnover and Malaysian banking sector is no exception. Therefore, the present study is aimed at exploring to deal with this burning issue with the help of career management practices and its impact on turnover intention. Data was analyzed by using PLS-SEM. The results of the study have important implications for the banks to deal effectively with the existing problem of employee turnover. Overall the proposed model of this study shows high explanatory power in understanding the concepts of career management to reduced turnover intention in Malaysian banking sector.

The growth of slums in cities is deteriorating the urban landscape and creating environmental crisis in the form of spreading of diseases, ill- health, malnutrition and making the city a center of crimes and other evils. The problem of slum growth is not only recognized in the metropolitan or million cities but also in the developing class I cities like Kharagpur. Kharagpur city is the fourth largest city and the fifth most populated city of West Bengal with a total population of  2,07,604 (2011) census in south–western part of Paschim Medinipur District, West Bengal. The objective of the present study is to analyze the educational status of the slum dwellers of Kharagpur city. Education is directly related with income and socio economic conditions. The slum dwellers are suffering from illiteracy and ignorance. This study is based on Primary data collected from 15 slums which included 396 households in Kharagpur city. Secondary data was collected from the Kharagpur Municipality Office, Meteorological Department Kolkata, Survey of India Kolkata, D.M. office of West Medinipur, Census Handbook and District Statistical Handbook etc. The excessive population growth rate, low level of income, illiteracy, lack of availability of proper nutrients are the basic drawbacks among the people living in slum areas. Employment opportunities, expansion of social education, cleanliness, recreational facilities have to be adopted for slum improvement and bettering the wellbeing of the slum dwellers in the city.

Research questionnaires are not always translated appropriately before they are used in new temporal, cultural or linguistic settings. Thus, the results based on such instruments may therefore not accurately reflect what they are supposed to measure. Gjersing et al., (2010). Research has shown that there were only a few literatures in counselling supervision that had been investigated, said Wan Marzuki Wan Jaafar (2011). This study aims to modify the Counsellor Performance Inventory (CPI) by Iannelli (2000) into Malaysian context. The original dimensions on CPI cover the following things: Counselling Skills, Counselling Knowledge and Interpersonal Relationship. This research is a research development aims to modify the original inventory into Malaysian context that considerate of the cultural and ethical practices and added a new dimension known as Professionalism and Ethical Practices. This paper was intended to explain the modification process involved in this study according to Stewart et al., (2012) recommended the researcher to include the reports of: 1) Features of the original measure that required modification; 2) Source of information on the basis for modifications; 3) Specific type of modification made; and 4) How the modified measure was tested for psychometric adequacy and results. Additionally, by implemented the modification on the instrument, it will get the gaps closer and measure what it’s supposedly to be measure.

This paper examines the impact of government policies on house prices in Malaysia. In addition, this study also includes the role of gross domestic product, interest rate and total population as emphasised by the Life Cycle and Overlapping Generation Models. This study used an annual time series data from 1988 to 2017. By using autoregressive distributed lag (ARDL) framework, we develop a model of house price determination with a focus on government policy. This study revealed that PR1MA has a positive association with house prices. On the other hand, MM2H is not a primary contributor to the house prices in Malaysia.

This study aims to provide empirical evidence on the relationship between generosity and intention to participate in Cause-Related Marketing (CRM) program directly or mediated by positive emotion. The quantitative study was conducted with convenience sampling to 54 respondents (92% return rate). The questionnaire included items to measure the attitude toward generosity, intention to participate in the CRM program and positive emotion. All data were analyzed using SmartPLS. The finding of the study is that there is a significant positive relationship between generosity to positive emotion and a significant positive relationship between positive emotion and intention to participate in the CRM program. However, the direct relationship between attitude and generosity to the intention to participate in the CRM program is not significant. This study has both theoretical and practical implications. The contribution to theoretical is that this study gives empirical evidence of the relationship between generosity and intention. The practical implication is that this study can give insight to the manager on how to use CRM to improve company relationships with customers.

Online marketing, also known as internet marketing, uses interactive, virtual spaces to advertise and sell goods and services. Additionally, modern internet-based, synchronous networking technologies have contributed to the transformation of major economic industries such as marketing. Being cost-effective, fast and enjoying an incredible global scope, internet marketing has yielded tremendous gains for various businesses. This impactful, new approach, however, also includes its particular difficulties, e.g. lack of face-to - face contact, privacy , and security, etc. that should be considered as part of this. The present study focuses on the impacts on marketing practice of internet-fostered digital spaces and also shows the analysis of various marketing strategies that a company can use to achieve its target. The paper starts with the definition of online marketing and the examination of historical context to use online marketing; various online marketing strategies, online marketing strategy, various claims by different authors, which will shed some light on The next focal point is the marketing possibilities which prevent the implementation of this new virtual space. The research continues with issues that arose from virtual space deployment in the marketing area, such as security and privacy issues, lack of confidence etc. We suggest the conclusions by considering the answers to the problems that lie ahead.

The purpose of this research is to test the moderating effect of perceived support in the link connecting work engagement and turnover intention. A set of 360 surveys was given out to academics in the tertiary institutions in Nigeria and SmartPLS to test the hypotheses. The results verified the effect of supervisor support moderates the effect of work engagement on turnover intention whereas organizational support was not supported. Therefore, to validate the findings, a longitudinal study is required. Future studies should aim to consist of public/private higher institutions of learning in Nigerian. This study supports evidence for supervisors intervening effect on the link connecting work engagement and turnover intention in higher institutions of learning in the country. This paper provides theoretical evidence and a managerial base for potential scholars since Nigeria lacks investigations on moderating impact on distinctive effects.

The recent QS 2021 World University Rankings showed that all five Malaysian research universities have improve and ranked among the world’s top 200. The improvement in the ranking is an indicator that Malaysian research universities are making continuous efforts in improving their research and academics. To achieve a better ranking, Malaysian research universities use key performance indicators for academicians. Academicians may feel burdened with the high expectations from the management. The present study intends to examine how psychosocial safety climate (PSC) influence academicians work-related attitudes such as work engagement and job satisfaction. The study also intends to examine if job demands mediate the relationship between PSC and work-related attitudes. The paper is the first study examining PSC and academician’s work-related attitudes in Malaysian research universities.

The purpose of this paper is to provide a hypothesized model which investigates the relationship of workplace spirituality and turnover intentions in the banking employees of Malaysia. This study was conducted on managerial employees of banking sector of Malaysia. Sample was drawn from different commercial banks operating in Malaysia for this study. A total of 381 usable returns were collected for the analysis. Structural equation model (SEM) through PLS were implemented to obtain the best fit model and to determine the role of Workplace spirituality to improve the turnover intentions in banking employees. As predicted, the hypothesized model best fits the data. The results of direct relationship analysis and SEM also contribute to the clarification of the causal relations between workplace spirituality and turnover intentions in banking employees. Moreover, the results revealed that the influence of workplace spirituality on turnover intention was significant in banking environment in Malaysia. Research limitations/implications – The results of this study might only be generalized to banks and similar contexts. Moreover, although the sample of the study was yielded from sample in Malaysian banking sector, the common methods bias might be a problem in generalizing the results. Workplace spirituality is the concept though which Banks can retain and their employees and workplace spirituality also helps the organizations to reduce the negative work attitude for employees. The results also helps the decisions makers to focus on building training programs in order to understand the benefits of enriching spiritual environment and be more supportive of spirituality movement. Furthermore, organizations can design some of activities that make work environment more meaningful.
This study is unique as it is the first that examined theoretically and empirically the influence of workplace spirituality on turnover intentions especially in the banking environment.

Palm oil industry in Malaysia has been in the limelight due to criticisms from various pressure groups on the severe sustainability issues as the results of palm oil productions and processes. Emerging sustainability issues expose palm oil industry to face the unprecedented set of sustainability risks. As such the identification of sustainability risks, the assessment of their impact, the development of sustainability risk management (SRM) to respond and monitor those risks are critical for organization in order to ensure company’s viability and survival in current business environment. Thus, this study intends to provide useful insights on the management of sustainability issues using risk management framework that includes risk identification, risk assessment and analysis, risk response, and risk monitoring. Questionnaires were distributed to operational managers in selected palm oil mills. Failure Mode Effect Analysis (FMEA) was employed to analyse the data. The findings reveal that sustainability risks are perceived as having major impact to business operations; they occur occasionally and are moderately easy to be detected. By assessing the impact of sustainability risks, an acceptable range of risk mitigation strategies can be assigned properly. This finding highlights the need for integrated sustainability risk management approaches to facilitate the development of effective sustainable strategies.

A standard economic model (i.e., Theory of Planned Behavior) is based largely on logical cognition (Ajzen & Fishbein ,1991). As a result, it is known for the rational component in the theory predominates in influencing the dependent variable that is intention; meaning that, TPB largely ignores the role of irrational influences in decision making. However, in reality, an individual decision is based on both rational and irrational forces (Micklitz et al., 2011; Mullainathan & Thaler, 2000). The study, being explorative, include Cognitive Bias as a moderator to predict female consumers purchase intention towards cosmetic products choice paradox. Hence, to the extent that it can incorporate the measurement of irrational variation, this study postulates that TPB can be improved as a model of behavioural intention. A self-administered questionnaire was employed to gather data from 380 consumers via purposive sampling and subsequently analysed using Partial Least Squares–Structural Equation Modeling (PLS-SEM). This study attempts to investigate if Cognitive Bias which is known as an irrational factor moderates, that is, either improves or reduces purchase decision of consumers due to the causal effects of Behavioral Beliefs and Attitude. As a result, it has been found that people's decision making is heavily influenced by the framing of the problem which is known as Cognitive Bias (van Schie & van der Pligt, 1995; Elliot & Archibald, 1989; Tversky & Kahneman, 1981); thus, Cognitive Bias violates Expected Utility Theory.

Indonesia has the fourth population rank in the world, the women’s population is greater than man. The increasing number of women’s population, along the growth of women’s labors in Indonesia who are active in the economy, it can be seen from the increasing number of Women's Labor Force Participation Rates from year to year. This is driven by the existence of the gender equality principle which is one of the targets in the Sustainable Development Goals (SDGs). The increasing population who work, both men and women have a role in economy. This research aims to study the role of women labors in Indonesia's economic growth 2015-2018. We used 34 provinces data from the publication of the National Labor Force Survey, the variables are economic growth, man labor, women’s labor and the number of poor people. The results in this study using panel data regression showed there is no spilover between women labors and man labors. In addition, the growth of women labors in Indonesia is not statistically significant on economic growth. While the growth of man labors and the government expenditure has a significant positive effect on economic growth and the growth of the poor population has a significant negative impact on economic growth.

Fraud and forgery are two types of crime in the land registration system. Both crimes are essentially involved in the deception of making dishonest personal gain for oneself or to create loss for another. Many countries have successfully converted their land registration records from paper documents into the computerised system. In Malaysia, since 1995, many different land administration authorities have offered their services through e-government instruments such as Computerised Land Registration System (CLRS) and Electronic Land Administration System (ELAS). Nonetheless, these innovations are factored as the cause in the increase of fraud and forgery cases. This study reviews the fraud and forgery challenges in land registration system innovations related to the information ownership. The fraud and forgery challenges in Malaysia include the (i) limited power of Registrar or land administrator, (ii) lack of expertise and resources, (iii) computerised land registration system security, (iv) lack of concern among legal practitioners and commissioners of oath, and (v) the abuse of power. This study also informs the land administration authorities and practitioners about the significance and challenges to protect information against the misuse for fraudulent purpose.

Many researchers state that the sense of “meaning” plays an essential role in shaping the place’s cultural identity and symbolism. The sense of “meaning” is manifested through the formation of identity and symbolism, which is considered universal because it influences human perception. The sense of “meaning” in an area forms valuable memories that make the place unforgettable due to the influence of the elements of identity and symbolism that exist in it. This study’s objective is to analyse the criteria elements of the cultural landscape in Pantai Lido that make up the sense of “meaning” from the perspective of Malays oldies in Pantai Lido. Furthermore, in achieving the objective, a qualitative method was conducted. It involved in-depth interviews and participant observation by collecting the informants’ perception, memories, attitudes, and beliefs as the subjective reality manifested at both of the psychological and social-cultural levels. The findings demonstrate the meaning of place as the factors that make Pantai Lido more noticeable and memorable. The results show that the meaning of place as a factor that makes Pantai Lido more unique and unforgettable. This study will carry on by suggesting a survey on the importance of meanings of place and its association involvement in developing a cultural landscape on the waterfront in Malaysia. This indicates that perhaps the local authorities and the policymakers need to improve and reshuffle the current regulations for waterfront development in Malaysia.

The objective of this paper is to explore the current level of learner autonomy and academic self-efficacy and relationship between learner autonomy and academic self-efficacy amongst English major students. A total number of 443 English majors students from eight universities in Hubei Province were chosen as respondents through two steps, stratified sampling and simple random sampling. In this study, two questionnaires were adopted to gather data from the 443 chosen respondents. After the data collection, SPSS 24.0 was used to process the data set to generate descriptive statistics and then Pearson product moment correlation analysis was utilized to find out the correlation between earner autonomy and academic self-efficacy. The outcomes of this research show that: firstly, the overall levels of English major students’ learner autonomy and academic self-efficacy are both moderate; secondly, there is a significant and positive correlation between English major students’ learner autonomy and academic self-efficacy, with the correlation coefficient value being 0.462; thirdly, there is a significant and positive correlation between the five dimensions of English major students’ learner autonomy and academic self-efficacy, with the correlation coefficient value being 0.421, 0.450, 0.279, 0.334 and 0.477 respectively; fourthly, there is a significant and positive correlation between the dimensions of English major students’ academic self-efficacy and learner autonomy with the correlation coefficient value being 0.423, 0.342 respectively. On the basis of the results of the investigation, this study further puts forward some strategies concerning the improving of English major students’ academic self-efficacy and learner autonomy. In addition, some recommendations for future research are also put forward

Climate change is causing severe hydrological perturbations commonly seen as erratic precipitation patterns in many regions. North-Western region of Pakistan is also facing severe rainfall decline which has rendered groundwater exploration crucial for the sustenance of agricultural and domestic activities. The integrated geophysical method described here employs Automatic Mapping Water Detector (AMWD) to locate aquifers with relative depths and Electric Resistivity (ER) Survey for investigating the groundwater salinity. AMWD generates output in the form of potential difference curves and profile map, which were interpreted combinedly to investigate the aquifers. ER survey, using Schlumberger configuration, was carried out at the demarcated location and the resistivity values were analyzed to establish a relation with groundwater quality. The AMWD and ER surveys were conducted at four locations. The first two, with known groundwater data, served to cross-check the results obtained from AMWD and ER surveys. Once the method validated, the remaining two locations (Sadiq and Baloch points) were explored with Baloch point showing auspicious prospects for freshwater availability but with underlying layers of saline water. Thus, the method not only aids in locating freshwater aquifers but also provides critical data for sustainable groundwater management in regions prone to both saline and freshwater conditions.

Numbers of private car dependencies in Malaysia nowadays are increasing every year. Due to that, Malaysian seems too way more comfort in travel by their owned vehicles. However, high numbers of vehicles on the road would tend to congestions in which areas that had big size of populations such as in urban areas and residential areas. Thus, it does not only require in congestions but it is highly exposed to traffic accidents among vehicles on road. This will determine on what are the level of traffic enforcement effectiveness of the areas. However, government has enforced the rules and regulations of road traffic to ensure the driver to follow the rules. This is because traffic rules and regulations implemented in order to improve the safety on the road. Besides, researchers believe that high rate of traffics accidents on road are related with the human behavior and attitude of the drivers itself. According to [1] stated that Perception of Being Caught (POBC) is a "feeling" of getting caught in a psychological term which relate with an act of awareness on road safety. In this study, researcher would like to determine the factors that influencing the private user’s Perception of Being Caught (POBC). These factors are the key to improve safety on the road. Government which acts as the responsibilities parties may use this result to increasing the road safety and decrease the road fatalities in our nation.

Purpose: The reason for this investigation was to check the notability of intrapreneurship for business education faculty members and look at how its credits and practices identify with faculty’s' work inspiration and socioeconomics.
 Design/methodology/approach: From a sample frame of 851 university business education faculty members in KPK region, Pakistan, 376 faculty members finished an online poll for a reaction rate of 44.1%. Results demonstrated statistically substantial contrasts in faculty members’ intrapreneurial introduction relying upon background, level and specialization of position, and university.
 Findings: Greater trust in and relevant help for intrapreneurship enhanced faculty encouragement. Responders who self-recognized as ambitious innovators encouraged coordinated efforts between their students and active businesspeople, directed new methodologies for showing inventiveness and designed creative educational programs. While responders for the most part felt a sense of freedom, they didn't feel they had satisfactory skills and resources for propelling new enterprises, and they saw less resilience for hazard and risks inside their universities.
 Originality/value: Discoveries of this examination may help separate explicit intrapreneurial characteristics and authoritative components that could strengthen faculty driven instructional method and lessen faculty motivation.

Medicinal plants and plant derived products have been part of the health care system since ancient human civilization. Traditional medicine uses plant extracts because of it’s antioxidant activity. In contrast usage of synthetic antioxidants are being restricted due to several limitations. Thus, there is always demand for newer and alternative phytomedicines. The aim of the present study is to analyse phytochemical components and to explore the In vitro antioxidant potential of methanolic extract of Enicostemma hyssopifolium (MEEh). The plant extract was prepared by organic solvents. The MEEh was used for GC/MS analysis and for exploring the prospects of Enicostemma hyssopifolium. The radical scavenging bioassays such as DPPH and ABTS were carried out to study in vitro antioxidant potency. The lipid peroxidation assay was performed to analyse their inhibitory effects and ferric reducing power of the extract was also evaluated. GC/MS analysis revealed that the plant is a rich source of phytochemicals such as 3,5-Dimethoxyacetophenone, Ergost-5-en-3-ol which are known to have antioxidant potency. In the antioxidant assay of MEEh the IC 50 was found to be 655.3>306.6 μg/ml. In lipid peroxidation assay, 33.45% of inhibition was found at 1000 μg/ml. The findings of the study revealed the potential of Enicostemma hyssopifolium as a source for natural antioxidants. It revealed that the plant could be a promising alternative agent in scavenging free radicals and may have ameliorative effect in complications associated with free radical damage.

The hospitalization of the victims suffering from certain diseases depend hugely over keeping an eye on the information repetitively. New wearable devices and technologies for this purpose are discovered to enhance the continuous monitoring of systems. This newly developed approach is recognized as body-body communion. Using the human body, we can convey various information, data and signals. Practicing this newly developed approach eradicates the existing complex structures which are composed of cords and wires. This makes it uncomfortable for the patient for prolonged hours. This increases the difficulty in critical patients especially the patients which tend to require immediate and timely assistance by the doctors and nurses. In this system, sensors are implemented on the body of the patients’ which regularly keeps an eye on the needed parameters. There are five respective sensors which are being used in this system. They are heart rate sensor, ECG sensor, respiratory sensor, humidity sensor and dust level sensors. Therefore we are able to determine the requirements and needs of the patient almost immediately and accurately. Information which is gathered is relocated from an intermediate network to a hospital. This can later be analysed on the respective customized gadgets and equipments or saved in the victim’s electronic database. Doctors are then able to interpret the problem by making use of the collected information, and can come up with a method of prescription and medication required. This is very helpful in reducing the time and complexity in the prescription planning and analysis. This helps to save a lot of time in preparing a treatment plan and to redeem medical reserves.

Three types of Iraqi truffles, which were collected from different regions of the Western Desert in Anbar Governorate in western Iraq, were studied. The three types of truffles were diagnosed as alhurqa truffles that are black-dark brown Terfezia boudieri ,and the second type is truffle aljabah that is brown-light-brown in color Terfezia claveryi.
The third type was white to creamy color, and brittle solid with zigzags and cracks in its outer shell Tirmania nivea . Models of soil grouped with the three types were studied to determine the chemical and physical properties of the soil, as well as the total numbers of bacteria and fungi present in the truffle rhizosphere were calculated. as well as the total numbers of bacteria and fungi present in the truffle rhizosphere. Amino acids, which differed between the three types, were diagnosed in terms of the quality and quantity of the amino acid, The truffle T. boudieri containing 14 amino acids whose values ranged from 0.011 ppm for Aspartic to 75.654 ppm for Arginine, the total concentration of amino acids was 239.609 ppm While T. claveryi contained 0.192 ppm Aspartic acid to 194.433 ppm Glutamic and the total concentration of amino acids was 346.633 ppm. At last T. nivea content 0.294 ppm Isoleucine to 233.555 ppm Alanine, and the total concentration of amino acids was 556.365 ppm. Soil characteristics varied between the three types of truffles. As well as the amount of nutrients in addition to the difference in the numbers of bacteria and fungi between the truffles types. The truffles oxidant results according to estimate Thiobarbituric acid showed higher value in T. boudieri (0.835) than T. claveryi (0.649) and T. nivea (0.486) mg m Malondialdehyde (MDA). kg truffles.

There is a global rise in the incidence of diseases like diabetes mellitus, atherosclerosis and cardiovascular diseases. Therefore, this study was designed to examine the effect of adding fine bran and date seeds powder as a sources of dietary fibers and active healthy components to prepare functional bread for lowering blood glucose and cholesterol levels. Sensory evaluation revealed that successful replacement of bread samples with 5,10 and 15% fine bran (Fb), 5 and 10% date seeds powder (Dsp) and the mixture of 5% fine bran + 5% date seeds powder. Bread supplemented with 10 and 15% fine bran contained 13.478% and 13.777% (g/100g) protein content respectively, while bread supplemented with mixture of 5% fine bran + 5% date seeds powder, and 10% date seeds powder contained 5.51 and 4.95 (g / 100g) of total dietary fibers respectively. The biological evaluation showed that rats fed on bread sample and its mixtures containing 15% fine bran , 5% date seeds powder, 10% date seeds powder and the mixture of 5% fine bran + 5% date seeds powder for 30 days significantly (p<0.05) reduced serum total cholesterol (TC), triglycerides (TG), low density lipoproteins (LDL), very low density lipoproteins (vLDL), while high density lipoproteins (HDL) increased. Also, data showed that rats fed on pan bread made from wheat flour substituted with different levels of fine bran and/or date seeds powder significantly lowered their blood glucose level.

gallstones are common diseases in many countries of the world , and incidence rate may reach about 20 % .Most cases of gallstones occur in females , the incidence rate may reach four times to one in comparison between women and men , mainly in fatty , fertile , age of forty female , gall stones are rare before age of 20 years ,but; may occur at any age . many cases are not diagnosed because they do not cause any signs or symptoms , and thus can only be diagnosed accidently by routine abdominal ultrasound.
The aim of study is to evaluate the relationship between age,sex and body mass index as risk factors for gallstone.
a cross sectional study was conducted in Tikrit city during the period from early of May to the end of October 2019 . 468 were enrolled in present study , and only 95 patients were diagnosed as a case of gallstone (29 male , 66 female). All patients attending private ultrasound clinic with different complains, data was collected by using certain questionnaire.
The results showed that, There was highly significant statistical relationship (P – value ≤0.05) between body mass index mean in both gallstone cases(26.628±5.808) and, in cases without gallstone(22.225±1.316). In the present study there was high statistically significant relation(P- value ≤ 0.05) between body mass index measurement above 25(31.97727273± 3.747859149) and measurement below 25(21.85882353± 1.616313889) in patients with gallstone.
The present study conclude that , Body mass index more than 25 considered as an important risk factor for gallstone.

The environment is an important component of human life and is one main study in in Islamic economic politics and legal politics in Indonesia. This study discusses the concept of environmental conservation in the perspective of Islamic economic politics and legal politics in Indonesia. This study is a qualitative research using the library research method. The results of this study have proven that environmental conservation is essential for humans to create benefits for people and avoid harm due to environmental damage. In Islamic economic politics, the rules on environmental conservation are found in the fiqh of environment, which is a standard reference for all Muslims. In Indonesia, such rules are regulated in the Law No. 32 of 2009 concerning the environment.

Web scraping, or web data extraction is data scraping used for extracting data from websites. Web scraping software may access the World Wide Web directly using the Hypertext Transfer Protocol, or through a web browser. While web scraping can be done manually by a software user, the term typically refers to automated processes implemented using a bot or web crawler. It is a form of copying, in which specific data is gathered and copied from the web, typically into a central local database or spreadsheet, for later retrieval or analysis.
In this paper, among others kind of scraping, we focus on those techniques that extract the content of a Web page. In particular, we adopt scraping techniques in the Web e-commerce field. To this end, we propose a solution aimed at analyzing data extraction to exploiting Web scraping using python and scrapy framework .

This paper presents a general methodology of optimizing the energy performance of a photovoltaic panel in five different cities in Morocco, by varying its slope and azimuth. A domestic wind turbine is also studied in Casablanca. For the same capacity, simulations in TRNSYS software prove that photovoltaic panels have a better yield than the domestic wind turbines. These wind generators can be coupled with the photovoltaic system in order to lessen the intermittence of the photovoltaic production at night and during short cloudy days.

In Morocco, forests are under severe pressure because of the intense needs of the population for land used for food crops and wood for domestic or industrial use. To this over-exploitation is added climatic and edaphic aridifications which accentuate the phenomenon of erosion, the degradation and the decrease of soil fertility. Consequently, alternative strategies based on the use of appropriate plants are needed to restore and / or to rehabilitate degraded lands and to improve crop production.
In many countries, Bituminaria bituminosa is used; this shrub has attracted considerable attention related to its important role in nitrogen fertilization, soil protection against erosion and significant productivity improvement (Yates et al.,2009).
Also, the purpose of this study is to evaluate the impact of Bituminaria-rhizobia symbiosis on associated plants such Atriplex nummularia.
So, a trial was conducted under-greenhouse at the Faculty of Sciences of Meknes (Morocco); there were pots with plants of Bituminaria bituminosa and Atriplex nummularia grown alone (monoculture) and others with the association of the two species.
At the flowering stage of the plants, the growth as well as the nodulation parameters including respectively height and dry biomass and number and dry biomass of nodules was evaluated.
The results obtained revealed that Atriplex nummularia benefited from its association with Bituminaria bituminosa as its biomass was high in comparison to its monoculture. Besides that, the growth and the nodulation parameters of B.bituminosa were improved in mixed culture.

Nanotechnology is regarded as the most imminent technology of 21st century and is contemplated as a big boon in the cosmetic industry. In the present investigation, non-aggregated cationic and unmodified nanoparticles (TT-C-NLPs10 and TTNLPs1) were prepared .In addition, spherical shape, crystalline architecture and cationic charge were also noticed. Furthermore, integrity and conformational stability of TT were maintained as evidenced by symmetrical position of bands and superimposed spectra, in SDS-PAGE and circular dichroism.

Educational administration is key to the realization of educational objectives. It helps in the systematic arrangement of educational resources to attain the set goals of the education. It is unfortunate that educational administration in Nigeria is facing numerous challenges that is preventing it from achieving it objectives. The aim of this article is to discuss the challenges facing administration of education in Nigeria. The article used secondary data which was sourced from print material and online publication. This article identified weak school administrators, lack of data to plan, inadequate funding, inadequate professional teachers, inadequate infrastructural facilities, institutions Corruption and insecurity as challenges preventing effective administration of education in Nigeria. To address the challenges preventing effective educational administration in Nigeria, the following have been recommended: appointment of competent head for educational institutions, increase the funding of education, provide adequate infrastructural facilities, fight institutional corruption, provide adequate security and generate reliable and creditable data for planning education.

The present comparative study was done between normal and patients with diabetes and kidney disease in Diyala city in Iraq. The studied ages were ranged between 40 and more than 69. Serum samples were collected from hospitals in Diyala province. The result revealed that the serum sugar values behave in different manner than that of urine and creatinine values. The result showed that male patients percentage (50.0%) was less than male controls percentage (56.0%), while female patients percentage (50.0%) was more than female controls percentage (44.0%) With no significant differences (P> 0.05) among groups according to gender. Blood sugar, blood urea, and serum creatinine were higher in males compared to females. in males blood sugar was higher According to age, the highest age periods in patients was (50-59 year) and in control was (40-49 year), while the lowest age period in patients was (30-39 year ) and in control was (>69 year ) with high significant different between groups according to age periods.
The mean value of serum sugar was high in the patients than control group with high significant differences between groups. The mean values of serum urea were high in patients from the control group with significant differences between groups. Besides, the mean values were significantly higher in Serum Creatinine in patients than controls. the mean value of Blood Sugar was higher in male patients than female with non-significant differences (P>0.05) among patients. So, the mean value of Blood Urea parameters was high in male patients than female with non-significant differences (P>0.05) among patients. Besides, the mean values of Serum Creatinine were higher in males patients than females with non-significant differences (P>0.05) between patients.
Blood sugar did not settled, it goes up and down between the age forty to the age over 69.The least mean values of Blood Sugar were between (50-59) year and the highest values were between (60-69) year with non-significant differences among patients age. On the other hand, the least mean values of Blood Urea were between (40-49) year and the highest values were more than 60 years with non-significant differences among patients age. Besides, the least mean values of blood urea and Serum Creatinine lied between (40-49) years. With age, these values were elevated.

Manufacturing is a critical demand-supply chain of production to meet consumption needs in fulfilment of contractual obligation under planned delivery schedule or on-demand as needed. This is particularly the case with certain manufacturing concerns that continue to advocate a normative practice of market-response or business-purchase reactions as and when it arises. The maintenance of capital-intensive production and high-cost related products are examples of a typical and common business process in operations management that is reactive rather than proactive. However, as a Business Process Improvement (BPI) strategy that works beyond the practice of normative manufacturing is this proposed model of configure-to-order (CTO) production through lean initiatives. It is a proactive change-driven flexible-adaptive manufacturing enabler that produces ever-shorter delivery times, with economies of scale, operational efficiency, systemic-aligned management and overall productive organizational effectiveness. A case in point is the agility of medical equipment and related products manufacturing business during an unexpected surge of not only critical demand but urgent-fast delivery for its products to combat the death-threatening crisis of Covid-19 pandemic onslaught. In essence, the adoption of ‘lean’ initiatives that incorporates a combined approach of ‘lean’ and ‘agile’ elements - capsulated in the acronym of ‘leagility’ – is a hybrid strategy that facilitates CTO production to deliver the output on time, the result-expected secured and outcome-anticipated fulfilled.

Globally, the COVID-19 pandemic has been the headline over the past few months and forced the institution and individuals to work remotely and practices such as social distancing. Consequently, the cybercriminals urgent implementation of technology to enable the organization to work remotely by conducting cyber-attack targeting critical organization within countries. This article discusses the different type of cyber threats and its impact to the organizations during COVID-19 pandemic by exploiting the digital and technology.

The grought of the internet services and application, the social media services and application become a major attraction of the user and organization. This lead to the extensive use of social media to achive different type of objectives that meet individual and also the organisation interest. Consenquantly, this use can creat a positive or negative impact. This article studies the impact of social media usage on the accadmic performace of the students. moreover, it illustrates the different impact based on the litreatue review on the types and the age of student. In addition to that, It doministrate the existed and related theories, reviewing the concepts and other studies related to the impact of socal meadia in related ot accadmic performance.

COVID-19 virus has now stunned the world. Mankind is not getting rid of this virus even after using all their strength. The cure for this disease has not yet been discovered which proves that the help of Allah is very important where all the strength of man ends. So now, Muslims and non-Muslims all are praying to Allah for help. Allah’s law is that He has created man to be worshiped. Whenever a person turns away from the worship of Allah and disobeys Him, Allah warns the people by sending various kinds of wrath or punishment on them. For example, Allah destroyed many nations, including the nations of Nuh (A) and the Boni Israil. Covid-19 is such a torment which is seen now. At present, people are moving away from the worship of Allah and at the same time, they are engaged in unjust, obscene and brazen acts. One nation persecutes another nation which is disliked by Allah as the Creator. As a result, He has sent down this torment to stun the whole world.

The Gulf Cooperation Council (GCC) countries) face the dual shock of a pandemic caused by the novel coronavirus (COIVD 19) and a collapse in oil prices. GCC countries many times experienced fluctuations in oil price and learnt how to deal the situation. However, the COVID-19 outbreak, being a new one, has created a lot of concern among GCC countries. This pandemic is causing turbulence to the economies of the GCC countries. Major industries that have been impacted in GCC countries due to COVID-19 pandemic include Energy, Aviation, Food & Beverage, Chemical, Retail & E-commerce, Travel & Tourism among others. Besides a major downfall in oil demand has been reported across the globe due to the effect of COVID-19. Due to this, many oil productions sites have been shut down or has to decrease production in the region. The closure of the industrial and commercial activities because of the pandemic would certainly affect their economies. Facility management (FM) constitutes a branch, jointly representing real estate market with property management and asset management. It plays a crucial role in economic activities in region as FM services are involved in all industrial and commercial activities. The Facility Management (FM) market in GCC countries has witnessed robust growth during the last few decades due to rapid economic activities in this region. It is an established fact in FM services manpower cost dominates the total cost whereas material cost plays vital role in construction industries. Majority of work forces in GCC countries in FM sector is migrant people from the Globe. CCC countries are showing actions that they are capable of acting effectively to contain the health and economic impacts of the pandemic within their own borders, albeit with marked shortcomings when it comes to protecting migrant workers. It is estimated that approximately 23 million migrant workers are living GCC countries . These millions of migrant workers across the Gulf face uncertainty as host countries lock down, employers withhold wages or mull redundancies, and strict coronavirus containment measures lead to deportations and confinement. This will have series impact on FM sector. In this paper a detail study the impact of COVID 19 on FM sector in GCC countries is reported. Strategies to overcome the crisis are listed along with the means and recommendation to implement the strategy.

Indian performance traditions have roots in ancient times. The flowering of those traditions in different directions and forms through the centuries has enriched Indian expressive systems although their development may not necessarily show any chronological or stylistic continuity. However, there are traces-tenuous, heterogeneous and hybrid-which are the crumbs that mark the genealogical networking of these varied foliations. But this is only to be expected as the centuries-old history of the vast subcontinent is fraught with radical changes and transformations. English plays gained more popularity through the following decades especially in the Presidency towns of Calcutta, Madras and Bombay and thrived with the patronage and participation of the officers of the East India Company. Plays by Shakespeare and other European dramatists becomes regular fare for playgoers. Such was the draw of these plays that sometimes actors and specially actresses were brought in from England. Gradually, more play houses were built and the audience began to include wealthy and literate Indians.
Mahesh Dattani has written many illustrious plays but his Final Solutions have been considered as the masterpiece among the other plays. It centers on the Hindu-Muslim problem Final Solutions foregrounds. It also tackles the theme of transferred resentment in the context to family relations. The large part of the play is good theatre and that makes it technically sound. The language is handled quite competently. Our present concern is with the play’s thematic side so let us focus on that. Dattani has attempted a neat balancing act when It comes to tracing the malady of communal disharmony to certain elements within both the communities-Hindu and Muslim. The diagnosis offered is also sound enough. Paid people cause riots or neither plays upon the susceptibilities of the two communities on certain key issues. The chorus is a good device to express the broad way in which the thinking of excitable elements within the two communities goes. Processions being taken out and then attacked and then relation somebody there always is who throws the first stone of the two communities are brought into focus.

Maya Angelou is one of the illustrious autobiographical poet, historian, lyrist, playwright, dancer, stage and screen producer, director, performer, singer, and civil rights activist. She is best known for her seven autobiographical poems. The themes encompassing African-American poet Maya Angelou's autobiographies include racism, identity, family, and travel. Angelou is best known for her autobiographical poems. Angelou’s autobiographical poetry occupies a unique position in her development as a poet. As a child, Angelou went through five years of self-imposed silence after she was raped at the age of seven by a Mr. Freeman, who was subsequently kicked to death by her uncle’s. The loss of her voice was a result of the trauma, which made her imagine that her voice could kill. Thanks to her teacher, Bertha Flowers, Angelou started writing autobiographical poetry and overcame her trauma. Autobiographical poetry thus played an essential part in the recovery of her voice, which in turn signaled the success of the healing process.

Coronavirus disease 2019 (COVID-19) prevails as an exceedingly transmittable disease, was first noticed in Wuhan, China, in December 2019. The disease has spread to most of the countries and territories around the world. India is not an exemption; the disease was first identified on 30 January 2020 in Kerala. The number of infected people in entire India is rising day by day. This study focused on the difficulties faced by elderly people who are predominantly affected during the span of COVID-19 Pandemic. Elders were mainly influenced by social vulnerability; especially experienced at the times of lockdown and quarantine were loneliness, anxiety and uncertainty can give rise to depressive disorders and insomnia. The challenges faced by the elders during COVID-19.

Nursing professional values are the moral knowledge which promote the ethical attitude of nurses, and guide their interaction with patients, colleagues, and community. These values affect the patient's safety and the quality of care. Therefore, it is important to consider its development within nursing education. Aim: identify nursing professional values and factors associated with its development: nursing students' perspective. Design: Descriptive research design was used .Setting: Faculty of Nursing, Alexandria University .Subjects: The subjects comprised of 314 students selected from second academic semester of the year 2018-2019. Tools: I Nursing Professional Values Scale Revised, II Factors associated with nursing professional values development from the students' perspectives. Results: It was found that 57.6% of the nursing students had a high perspective regarding the importance of nursing professional values, and 72.6% of them had a high perspectives regarding the factors associated with the development of nursing professional values, statistically significant correlation was detected between nursing students' demographic , academic data and their levels of perspectives regarding the importance of nursing professional values, in relation to age, residence, academic semester, and academic achievement in previous years (GPA).Conclusion: nursing students perceive caring, justice, and activism to be more important than trust and professionalism as nursing values. Also factors which affect nursing values development are; respectful relationship with nurse educators, work conscience, valuing nursing as a profession, the nursing staff as a role model, educational degrees. Recommendations: Educational workshops about methods of teaching of nursing ethics and values should be given to nursing educators.

Alzheimer's affliction (AD) is a degenerative character illness that affects people and is acknowledged to be the most, for the most part, saw the reason behind dementia, regardless, dementia can in like way be recognized by various contaminations and conditions. Dementia is a specialist term which is utilized to depict plenty of appearances, and there are a wide extent of sorts of insanity comprising Alzheimer's Disease, vascular insanity, dementia with strange, and others, yet dementia of the Alzheimer's sort (AD) is by a wide margin the most amazing clarification for dementia and this is the kind of dementia this speculation is worried over examinations on the Alzheimer's disorder Neuroimaging Initiative database exhibited that the proposed estimation not simply practiced ideal figure execution over top tier forceful strategies yet also reasonably recognized naturally significant models. The subjects are named unequal or not using AI systems. Henceforth it distinguishes the antigen framework by utilizing clonal determination. The makers have pre-taken care of the data. So it characterized the information mining methods to discover the antigens handling in AIS (Artificial Immune System). At that point, it needs to foresee the negative framework in the antigen separately. It recognizes utilizing the CLONAX calculation to give an ideal arrangement.

This article propagates the guests feedback on tourism experience based on the three major quality factors: service, facility, and location. We employ a descriptive quantitative survey and utilize five dimensions of SERVQUAL to determine guests expectation and perception from lodging experience offered by the chalet and resort entrepreneurs along the beach coast of Pengkalan Balak, Malacca, Malaysia. A total of 152 tourists who stay at five selected chalets and resorts are selected using a random sampling technique for the sample of the study. The results of the analysis indicate that the guest expectation on the service quality, the facility, and the environment is higher compared to guest actual experience during their stay in the designated premises. It is evident that the customer satisfaction level is low and the lodging providers are advised to take proactive measures in ensuring the quality of the service, the facility and the convenience of the location are at the global standard. It is important to note that the findings do not generalize to other lodging facilities, for example, hotel and homestay services. The findings from this study projects and assists chalet and resort entrepreneurs to advocate salient improvement for quality standards which ultimately flourish customer satisfaction level and discern best strategies in promoting the beach coast of Pengkalan Balak to be one of the best coastlines and finest chosen tourism destination in Malaysia.

Less was known about predicting factors concerning students’ knowledge, interests, and motivation towards Technical and Vocational Education and Training (TVET). The study aimed to determine the relationships among pre-secondary school students’ demographic factors, knowledge possession, interest and motivation related to TVET stream and to identify the relationship between informational methods and knowledge possession, interest and motivation of students towards TVET. A quantitative descriptive study used to determine the factors contributing to student’s knowledge, interests, and motivation, which play a critical role in 64 pre-secondary school students’ choice of TVET. A questionnaire was utilized to determine the participants’ perceptions of choosing the TVET field. Descriptive and inferential statistics, including one-way ANOVA analysis, were used to analyze the data. Findings revealed that information delivery methods such as receiving information from teachers, parents, peers, internet platforms with motivation have a significant relationship for students to choose TVET. Thus, the promotion and strategy on empowering TVET is salient and developing a positive image on TVET will encourage myriad stakeholders on the importance of TVET for the nation. It is a high time to rebrand the image of vocational education as an element to train skilled human capital development.

The probing of the human body is done using different modalities of medical imaging. The explications of various images require different methods of image processing which enhance their visual interpretation. These image analysis methods may provide images for different application using automated or semi-automated methods. The processed images may be widely used for data mining, feature selection etc by retaining the underline information and eliminating the irrelevant features. These techniques do not focus on the acquisition of the images. Computations and analysis of various images is the main thrust of MIP (Medical Image Processing) techniques. In general MIP can be categorised further into different physiological modelling or segmentation or registration of the image .This paper presents a survey on various feature selection methods used in medical imaging wherein most of the techniques and methods like Screening, Scanning, Selecting, etc. are summarized.

The growth of irregular cells within the brain region with the prearrangement of tissues is characterized as a Brain Tumor that leads death to people. Comparing to other categories of cancers, a brain tumor is the most deadly disease that has to be detected and treated in the previous stage. Due to cells' complex formation, the tumor detection process is complicated with simple image processing methodologies. Moreover, for providing proper and efficient treatment to the patients, an exact cancer segmentation and classification technique must process the input of brain images as Magnetic Resonance Imaging (MRI) scans. Based on that, this paper develops a novel approach called Soft Computing based Brain Tumor Detection and Classification (SC-BTDC) with the obtained MRI. In the present scenario of tumor detection from image processing, soft computing techniques play a significant role. Hence, it is adopted in this work. The method contains phases such as pre-processing, Fuzzy c-Means clustering-based segmentation, feature extraction, and image classification. The median pre-processing filter and edge detection methods are incorporated for noise removal and clearly define the image in the stage of the median pre-processing filter. Further, FCM based clustering is performed for the image segmentation process, following, factors of Gray Level Co-Occurrence Matrix (GLCM) found feature extraction is established. The final phase includes the classification process using the soft computing technique called Artificial Neural Network (ANN) classification. The proposed system acquires a higher accuracy rate and is compared with various existing algorithms for proving the efficiency and minimum loss of the proposed algorithm.

The study aimed to identify the level of psychological loneliness of female athletes with special needs, to identify the level of physical self-acceptance of female players with special needs, and to identify the relationship between psychological loneliness and physical self-acceptance of female players with special needs, and the researcher assumed the existence of Statistically significant differences in the sense of psychological loneliness of female athletes with special needs, and the presence of moral differences statistically significant for the physical self-acceptance of the players with special needs, and the presence of statistically significant differences in the feeling of psychological loneliness and its relationship to the physical self-acceptance of the players with special needs As for the third chapter, the researcher used the descriptive approach, and the study sample was deliberately chosen from the Paralympics players (with mobility impairments) in the Kateen Sports Club, as the research community consisted of (75) players. Weightlifting players (bing press) were selected for the 2018 season. In 2019, their number (12) players and their ages range from (18-20) years, with a percentage of (16%). Psychological acuity and measure of physical self-acceptance in research.

The study aimed to identify the level of eating disorders among students of the College of Physical Education and Sports Sciences - University of Diyala, to identify the level of emotions among students of the College of Physical Education and Sports Sciences - University of Diyala, and to identify the level of mental alertness among students of the College of Physical Education and Sports Sciences - University of Diyala, And identifying the existence of a relationship between eating disorders and its relationship to emotions and mental alertness among students of the College of Physical Education and Sports Sciences - University of Diyala, either assuming the research, the researcher assumed the existence of significant statistical differences between each of the eating disorders scale (bulimia nervosa) and the scale of emotions and the mental alertness scale of Students of the College of Physical Education and Sports Sciences - University of Diyala, and the existence of statistically significant differences between eating disorders, agitation and mental alertness among students of the College of Physical Education and Sports Sciences - University of Diyala, but in Chapter Two the researcher touched on issues related to research variables, and in Chapter Three it has The researcher used the descriptive approach using the survey method. Either the research sample was randomly selected from the students of the College of Education Physical education and sports sciences - Diyala University for the academic year 2018-2019 of (60) students and their ages range from (19-21) years. The researcher used the Eating Disorders Scale, the Emotion Scale and the Mindfulness Scale, but in Chapter Four the research results were presented and analyzed. Chapter Five, the researcher reached conclusions, which are the existence of significant differences between the scale of eating disorders (bulimia nervosa), the scale of emotions and the scale of mental alertness among students - Diyala University, and the existence of a significant relationship between the scale of eating disorders (bulimia nervosa) and the scale of emotions and scale Mindfulness among female students of the College of Physical Education and Sports Sciences - University of Diyala, and the researcher recommended the necessity of preparing and setting up a guiding and directive program to educate students about the topic of eating disorders and the factors causing it, and preparing seminars and lectures to raise awareness of the transformation of eating disorders and its relationship to psychological variables and its negative effects on psychological disorders, and conduct more negative studies on the psychological state.

The research aims to identify the psychological hesitation and self-confidence of the first-stage students in the College of Physical Education and Sports Sciences - Diyala University, and to identify a relationship between the two variables, and a researcher assumed that there is a statistically significant relationship between the frequency and self-confidence of the students, as the researcher used the descriptive approach in a manner Relational relationships to solve the problem, and the research sample consisted of (30) students, and they were randomly selected by lottery from the population of (60) research, as it represented (50%) of the original community. The researcher reached conclusions that there is a significant association relationship between Hesitation and self-confidence in the effectiveness of the field and the field, and the presence of a difference in the degree of hesitation and self-confidence of the students, and through the conclusions the researcher recommends that the trainers and teachers should raise the morale and create hope in the sample to get rid of the frustration that in turn leads to hesitation during the performance, and interest in enhancing self-confidence from By showing courage, strong will, persistence and determination, making positive thoughts about performance and avoiding negative thoughts in order to improve the perception about their abilities. Dunia, and conducting studies similar to the current study on games and other sporting events.

Diabetic wounds are a popular health problem affecting 15% of diabetic individuals. Traditional treatment depends on understanding the relationship between diabetes and wound healing mechanisms. Recent studies tend to use natural products that possess active components for treatments. Luteolin is the most common flavonoids found in many medicinal plants. The study has also highlighted the recent advances in the therapeutic effect of luteolin, particularly, on diabetic wounds healing. Luteolin has demonstrated its anti-inflammatory effect through its impact on fibroblast cell proliferation and migration. Further studies are highly recommended to focus on luteolin as an anti-inflammatory agent in human diabetic wounds healing.

Cold ocean and sea spots of our planet shroud a ton of assets and privileged insights. The investigation is impossible without the assistance of specialized methods. The submerged unmanned vehicles and sensor systems constitute the most important parts of the collaborative network and correspondence frameworks. This paper presents a study on submerged acoustic correspondence and route in states of chilly water and icicle-secured oceans and seas. All the preferences and impediments of considerable number of strategies like FSK, PSK OFDM, CDMA and so on in submerged acoustic correspondence are summed up, checked on and contrasted concurring with their long periods of distribution. Moreover, the works are looked at dependent on the multifaceted nature and execution of the calculations while some future exploration issues are also explored and distinguished.

This paper examined the performance of a light shelf (LS) as a delighting device for reducing electric light usage in a south-oriented open-plan office (OPO) under the sky in the tropic using Integrated Environmental Solution Virtual Environment (IES VE). Results showed that the LS improved daylight quantity of the one-sided light office by reducing the excessive illumination at the area close to the window opening but increased it at the back where the illuminance is low. The improvement at the rear was from 1.55 % (LS 3 at noon on 21st March) to 2.99 % (LS 2 on 22nd June at noon). The LS also improved illuminance uniformity for visual comfort in the room with the best three test cases ranging from 74.07 % (LS 2 and 7) to 76.67 % (L3) compared to the case without LS. The selected test cases showed higher illuminance distribution between adjacent points or possible sitting position in the room than the base case (BC). The reduction in electric light usage ranged from 11.78 % (LS 3) to 15.97 % (LS 2). Hence, the paper concludes that LS improved daylight and electric energy efficiency. Therefore, the LS 2 is recommended for the south-oriented OPO with one-sided lighting in the tropical climate.

Recently, there is rapid interest in the study of Underwater Wireless Sensor Network (UWSN), which is due to it verse applications such as pollution monitoring, seismic monitoring, equipment monitoring, disaster prevention, tactical surveillance, oceanography data gathering, and assisted navigation. Meanwhile, the realization of these applications is confronted with some underwater limitations namely, acoustic channel constraint, limited bandwidth, and water pressure. Several routing algorithms have been developed to achieve efficient data gathering. However, these algorithms are challenged with communication void problem. The communication void problem leads to packet drop/error and high energy consumption in the course of data packet forwarding. Therefore, in this paper, an improved communication void avoidance mechanism for UWSN has been proposed for handling void hole during data packet forwarding considering dislodgment of sensor nodes. The performance of the proposed mechanism has been evaluated against the adapted adjustment mechanism to confirm its benefit based on different data packet forwarding and energy efficiency metrics.

Most organizations have failed in completing their projects due to different factors such as funds, planning, time, manpower and others factor. Various frameworks or guidelines are practiced by organizations to strive against the existing challenges. Project management office (PMO) can be defined as an emerging concept that defines and maintains the standards of project management within an organization. In the UAE, even though most of the public sectors implement the project management strategy, the majority of organizations are still following the traditional practices. The main objective of this paper is to analyze and provide a review of the literature on framework for establishing project management office practices.

Background: While factors influencing e-training use intention has been mostly investigated based on the experiences of the developed countries, such investigations in the in the developing countries have been largely overlooked by researchers. Purpose: This paper extends the technology acceptance model (TAM) by investigating the roles of computer/internet self-efficacy and organisational support on intention of employees to use e-training. Methods: Three hundred and one responses collected from five public universities were in the study. Structural equation modeling was applied in data analysis. Results: The findings show that computer/internet self-efficacy, organisational support and perceived usefulness have positive and significant effects on intention. Likewise, perceived usefulness was found to have influenced the effects of internet self-efficacy, organisational support, and perceived ease of on intention. In addition, importance-performance matrix analysis (IPMA) was performed and the results suggest that emphasis should be given to organisational support and perceived usefulness for successful implementation of e-training. The paper has established the applicability of the TAM in predicting e-training use intention and the significance of organisational support in implementing e-training. In addition, the paper provides a model for understanding employees’ intention to use e-training which can be tested in other countries or in different contexts.

Literally, the concept of community-based enterprises (CBEs) is an originally practiced by community who are living in a small village located in Oyama, Oita, Japan in 1961 through a program One Village One Product (OVOP). Essentially, the model of CBEs which included the factors of cooperation, sustainability and innovation is enhancing the development of business performance among rural communities. In Malaysia, the program of One District One Industry or known as Satu Daerah Satu Industri (SDSI) is virtually practiced the model of CBEs with the purpose is to alleviate poverty among community in rural area. At present, most of rural entrepreneurs are less practiced the factors of cooperation, innovation, and sustainable enterprises as variables in CBEs model in their business activities. Therefore, the purpose of this study is to investigate the impact of CBEs model on business performance among entrepreneurs under SDSI program who are operating their business in East-Coast of Peninsular Malaysia. Hence, the method of this study is based on stratified random sampling which covers 230 respondents who are operating their business in the East-Coast of Peninsular Malaysia. Furthermore, the results indicate that all of the respondents in this study are significantly accepted the factors in a model of CBEs are contributing to their business performance improvement. Then, this research has proved that CBEs model is an essential platform to be implemented in helping the SDSI entrepreneurs as well as improving their business performance.

Malls and shopping buildings are part of public spaces, where communication is established, buildings and shopping centers in the capital city of Jakarta are developing, accompanied by increasingly modern technological developments. Monotonous appearance has now changed drastically and significantly. Technology and design take an crucial role in this stage of development, from the use of standard lamps which are now completely changing with the presence of urban screens, Light Emitting Diodes or LED, electronic components that emit monochromatic light.
Light Emitting Diode takes an important role in changing the appearance of buildings and shopping centers, now has a function as an advertising medium other than as aesthetics in Jakarta and other big cities. Nowadays shopping centers not only offer products but have turned into a gathering place for urban communities as a lifestyle, shopping centers are becoming meeting places and promotional events. Buildings and shopping centers now have a reciprocal (causal) relationship with urban spatial planning, architecture, and design that characterize urban society. In addition, Light Emitting Diode as an urban screen changed its function to become advertising communication media and create a metropolitan building that shines and has aesthetic value in the touch of technology.

SME development is an important pillar of regional integration efforts. Micro, small and medium-sized enterprises represent around 97 to 99% of the enterprise population in most ASEAN countries. In Indonesia, small and medium-sized enterprises made up 99.99% of total businesses and employ 97% of the workforce. Based on data from small and medium-sized enterprises that are already using the internet in Indonesia, the use of e-commerce is still between 9 and 15%. One of the innovation types was frugal innovation, which can be defined as products, services, or solutions that arise regardless of financial, human, technological or other resource constraints, and where the end result is cheaper than competitive offers and meets the needs of customers who have not yet been served otherwise. The objective of this research is to investigate the impact of digital business adoption, frugal innovation, and organizational innovation on firm performance. The study was conducted using a descriptive quantitative method in Indonesia. A structured research questionnaire was developed using a Likert scale-four. Data from a total of 100 returned questionnaires was analysed with SEM-PLS. The results of this research show how the performance of small and medium-sized enterprises (SMEs) is affected by digital business adoption, frugal innovation and organisational innovation.

Indonesia is the only South-East Asian nation to participate in the G20. Based on data from 'The Role of SMEs in Asia and Their Difficulties in Accessing Finance', one of the four countries in Asia with the largest percentage of SMEs is Indonesia (99.9%). The authors will conduct this particular investigation on SMEs as they play a vital role and have a huge impact on the economic development of Indonesia. According to survey results from Price Waterhouse Coopers in 2014 regarding family businesses, 95% of businesses in Indonesia are owned or managed by families. Previous findings from family enterprise research show how family engagement as a function of family business positively affects the relationship between innovation and enterprise success. More than 1.022.213 publications released between 2014 and 2019 were screened using the keywords: digital business adoption, e-business adoption, e-commerce adoption, family commitment, family firms, SME innovation, and SME performance. Eventually, for this study, 21 journals were selected based on this analysis, the conceptual model has four possible connections: the good relationship between digital business adoption and SME achievements; the positive relationship between the adoption of digital business and innovativeness; the positive direct impacts of innovativeness on family-firm performance; and a good relationship between SME performance and family commitment and innovativeness. This research refers to a conceptual framework that could play a major part in the success of SMEs through digital business, family commitment, and innovativeness.

The course "Basics of Quality Management", an elective and liberal course for undergraduate level in UKM. The course represents an important effort in producing quality conscious professionals who will be able to utilise the knowledge for the betterment of the organisation and society. The study is guided by the following research questions: (1) What is students’ expectation in learning about quality management concepts?, and (2) How does this course add value to the students’ future career? Research participants consist of 62 undergraduate students from different faculties who registered in this course in the first week of the semester. This study employed qualitative method, where research participants were asked open ended questions in Google Form. Their responses were then analysed into themes. Their expectation in learning the course can be categorised into three themes: that they expect this course would enable them to (1) understand quality concepts; (2) be more quality conscious, and (3) solve quality-related problems related in theri personal and professional domains. Regarding the value-added importance of this course, three themes emerged, that (1) to prepare for their future highly specialized and sensitive nature of their future career; (2) to add competitiveness nature of their aspired new business venture, and (3) to inculcate quality in their professional life. This study serves as an opportunity to gain insight into student perspective into their choice of this course as one of their elective and how this course can add value to their future career.

Background: The inferior alveolar nerve block (IANB) is the most frequent regional anaesthesia technique used in dental procedures and has been reported to have the highest failure rates among dental undergraduates, interns and even, dental professionals. Hence, local anaesthesia has been formally taught in worldwide dental curriculum since the 1940s. This was when lignocaine was introduced as the safest anaesthesia medium for dental anaesthesia. Otherwise, dental anaesthesia was performed by Horace Wells in 1920s using cocaine. Purpose. This study is mainly aimed to examine the difference between Year 1 and Year 3 dental undergraduates towards perceived attributes of innovation diffusion theory and intention to use a Novel Local Anaesthesia Simulator Kit (LASK) in competently performing inferior alveolar nerve block in pre-clinical simulation. Methodology. A cross-sectional survey was conducted using questionnaire; and distributed to dental undergraduates. A total of 150 questionnaires were valid for data analysis. Results. The findings revealed that the perceived attributes of relative advantage, compatibility, observability and trialability were statistically different for both groups of students. However, results indicate that complexity construct for both non-clinical and pre-clinical groups of students were not statistically significant difference. Conclusion. The findings of this study will contribute to specific educational significance in the dental curriculum, especially in assessment of dental undergraduates’ clinical competence dental undergraduates at a more microscopic level.

A simple linear regression is commonly used as a practical predictive pricing model of used cars. The concept of maximum predictive pricing or efficient frontier model is a popular notion in capital asset pricing model. A non-linear model has been observed to provide a better estimate of price appreciation while describing real-life phenomena. The objective of this paper is to develop a new S-curve model on the maximum predictive pricing of used cars. A dynamic S-shaped Membership Function (SMF) was used as a base function to formulate a new S-curve maximum equation model. A comparison between linear regression, cubic regression, and S-curve model has been made prior to formulating a new S-curve maximum predictive pricing model. Validation of the new S-curve maximum predictive pricing model was done by curve-fitting the new equation into the required data set. This new S-curve model is expected to represent a better and practical model related to the price prediction of used cars and specifically, can offer a more realistic forecast of used car pricing in Malaysia.

This research discusses the factors impacting the use of social media marketing on sales of the online small businesses in Malacca. The primary data was collected by using explanatory survey. The sample consists of 150 respondents who are online small business owners and who had experiences or non-experiences by implementing the social media marketing on their business in Malacca. The requirement analysis test used are pilot test, Reliability Analysis, Validity Analysis, Descriptive Statistic Analysis, Pearson’s Correlation Analysis, Multiple Regression Analysis and Hypothesis Test Analysis. The data analysis technique is used Statistical Package for Social Sciences (SPSS) Version 25.0 software. There are four independent variables such as customers’ feedbacks, communication, content sharing and customers’ relationships will be measured to examine their influence on sales performance of the online small businesses. The research results show that customers’ feedbacks has no direct influence on sales performance, communication has directly influence on sales performance, content sharing has no direct influence on sales performance and customers’ relationships has directly influence on sales performance of online small businesses in Malacca. In overall, the customers’ relationships has been proved to be the most significant factor that impacting the use of social media marketing on sales of the online small businesses because fostering relationships helps the online small businesses to build a positive rapport with customers within the community. The good customers’ relationships will make customers to have a good impression for the business owners and willing to repurchase the products. The achievement of this results could be a reference which offered the knowledge of sales performance on online small businesses for academic purpose, business study or other fields.

Root resorption is one of the most relevant problems in orthodontics that does not have a clear-cut method of resolution or prevention. We can use lighter forces and create an environment that would minimise the chances of developing root resorption, but nonetheless, there is no fool-proof method or mechanics to completely avoid the development of this malady. Moreover, the multifactorial etiology and other such considerations make it difficult to arrive at a conclusion whether this phenomenon can be effectively controlled at all. What we have now are a set of guidelines that were the result of intense research studies performed by pioneers in the orthodontic field. Utmost care and regular follow up are the only way to reduce the adverse effects and achieve stable and consistent treatment results.

Cesarean section is the most frequent surgical procedure in obstetrics. This study was carried out to isolating and identifying bacteria causing cesarean section inflammation from patients and antimicrobial susceptibility test to bacterial isolates; 30 samples were collected from patients with different aged of women that had suffering from Post-Cesarean section Infection in Bent-Al-Huda & Al-Habboubi hospital in in Thi-Qar province. The isolates were identified on the bases of their morphological characteristics, the Gram stain reaction, biochemical tests and confirmed by the Api 20 E test. The results revealed that the rate of bacterial isolates in patients with Post-Cesarean section Infection was (76.6%). out of these (34.8 %) were E .coli, (30.4%) were Pseudomonas aeroginosa, (13%) of Staphylococcus aurous, (8.6%) isolates of Acintobacter and Bacillus. Antimicrobial susceptibility testing to 23 bacterial isolates showed variable sensitivity to antibiotic, they were more sensitive to chloramphenicol and Imipenem also the results appeared increasing prevalence of multidrug resistant between isolates.

Environmental extremity or adversity is one of the dominant problems in world wide. For this, the main concern of ethics is to provide a crucial and a cogent remedy for sustainable development. Due to maximization of certain issues concerning sustainable development this paper intends to demonstrate virtue ethics as a method in terms of which such issues can be minimize. An appropriate structure for sustainable development can be attainable through the application of virtue ethics and its implementation in the daily life of human beings. Here we discuss about the virtue ethics which is considered as the character of human being that helps them in attaining a good life. Therefore, virtue ethics is important to study in order to establish a behavioural and habitual foundation that can be conducive for sustainable development. The prime motto of virtue ethics is to discover the protective and potential character of human being which can be more effective for sustainable development.

Background: The present study was conducted to assess utilization pattern of various cervical cancer screening methods and their outcomes among outpatients of tertiary care hospital.
Materials & Methods: 140 women age ranged 20-50 years were recruited. A questionnaire was developed and distributed among all subjects and asked to fill it and return it. Awareness and utilization and pattern of cervical screening was noted.
Results: Age group 20-30 years comprised of 40, 30-40 years had 60 and 40-50 years had 40 subjects. Education level was upto primary in 65, secondary in 45 and no education in 30 subjects. 90 were married, 25 unmarried and 15 were widow. 98 had awareness and 42 had never heard about it. 55 utilized it and 85 never utilized it. The difference was significant (P< 0.05). The type of methods of screening was PAP’s smear in 15, VIA in 35, VILI in 10, frequency of screening was yearly in 35, once in 20 and never in 85. Accessibility to results of screening was 25 received results of screening, 10 not received results of screening and 20 did not indicate receipt of results of screening. The difference was significant (P< 0.05).
Conclusion: Authors found that there was lack of awareness and utilization of cervical screening among subjects. Most commonly used methods was visual inspection with acetic acid.

Orthodontic appliances with mini implants became more popular in the field of orthodontics for past many years .There are wide array of mini implant designs, various materials are available for a variety of clinical uses in orthodontic practice. Absolute anchorage facilitated by mini implant system plays foremost role in successful orthodontic treatment .This literature review explains about historical background, parts, materials, types of mini implants and various clinical application in orthodontic purposes.

Ovulatory dysfunction being one of the commonest cause of infertility requires further evaluation to understand the relation between failure to conceive and a successful reproductive outcome. In this study comparison is done between the flow velocitiy indices in the uterine and ovarian artery during the luteal phase in both ovulatory and anovulatory cycles. It has been tried to ascertain if there is any correlation of the serum progesterone value along with the Doppler flow velocity indices. Very minimal number of studies so far has included all the above comparison and correlations in their study. Women with impaired perfusion can be supplemented with vascular enhancer drugs to improve the ovulatory rate.

The study included identification of Leishmania parasite from cases of cutaneous leishmaniasis, by examination of smears from patients and Nested-PCR technique ,Out of 215 cases suspected for cutaneous leishmaniasis included (61) pus and (178) tissue these pus sample were diagnosed by direct smear method to see the Amastgote phase .The cases included in this study belonged to some hospitals in the Babylon as Morjan Medical City Hospital (24) , Musayyib General Hospital(17), Thu Al-Kifl General Hospital (29) and Hashimyah General Hospital(145), during the period from (October 2019 to March 2020). According to stain results,(60.6%) from the (61) total pus sample cases were positive to giemsa stain and after that used the DNA extraction from total number (215) sample in Nested–PCR and the results appear in percent (82.7%) ,these percent divided in to (20.7%) to Leishmania. Tropica and (79.2%) to Leishmania. Major. The study aimed to detection of Leishmania species in Babylon province

Problem- Based Learning strategy (PBL) is one of the innovative teaching strategies that are used in undergraduate nursing education to help students learn how to apply knowledge effectively in a variety of clinical situations. PBL is considered as a convenient teaching and learning method for obstetric and gynecological nursing students. It also relates to its clinical practice to deal with and solve women’s problems. Purpose: This study aimed to explore nursing students’ perspectives about problem-based learning strategy used in Obstetric and Gynecological Nursing course. Design: descriptive exploratory research design was used in this study. Setting: This study was conducted at two scientific nursing departments at the Faculty of Nursing, Alexandria University namely, Obstetric and Gynecological Nursing Department and Pediatric Nursing Department. Subjects: The total number of students was 495 students. Tools: One tool was used for data collection: Nursing Students' Problem-Based Learning Strategy Perspective Questionnaire. Results: this study revealed that nearly more than three quarters of the students have a positive perspective toward PBL strategy. Conclusion: problem-based learning strategy is a valuable teaching method helped in achieving students' satisfaction regarding improving their learning skills. Recommendation: Problem-based learning strategy should be considered as a significant teaching method to be applied in different courses at the Faculty of Nursing. Moreover, Training workshops should be conducted to all nursing educators to enhance their abilities and competencies in the use of PBL strategy.

Data mining has become a usually utilized strategy for the examination of hierarchical information, for motivations behind summing up information in valuable manners and recognizing non-insignificant examples and connections in the information. The paper presents consequences of exploration on impact of information discretization on proficiency of Naive Bayes classifier. The investigation has been carried on datasets established on writings of two male and two female writers utilizing the WEKA Data mining programming system. The paired grouping was performed independently for both datasets for wide scope of boundaries of discretization measure so as to examine reliance between methods of discretization and nature of arrangement utilizing Naive Bayes technique. The mathematical aftereffects of tests have been thought about and examined and a few perceptions and ends planned

Identity is something that defines a person and gender is one aspect of it. Nature has bestowed all the living beings with gender binaries, be it an animal, bird or human beings. Later the concept of gender is redefined with the advent of third gender; The ones who are trapped in the body of the opposite gender. This study throws light on such a third gender woman and her traumatic experiences in the journey as a transwoman, her identity rooting and the problems from the public, acceptance issues and crises; Living Smile Vidya. Through her autobiographical narrative, her problems and identity issues are read in a trans feminist perspective. Thus, this study will be an awareness and appeal to the society on accepting the third gender, trans women, on par with women. They too have their rights to be a part and parcel of the society as they are just “trapped in the male’s body.”

The Quality analysis of online higher education websites is very important now a day. As such most of the quality parameters are defined to measure the quality of these websites. The paper is an attempt to make proper analysis of higher education websites. The research involves the creation of a database that includes well-defined parameters. Details are provided as an input to a learning model based on a vector support machine for comparison and ultimately geographical location. Testing the efficiency and accuracy of the database prepared for this task. This data was developed for seven different training, testing and verification on websites using support systems (SVM) algorithm. Algorithms trained with this database have proven to work well in site testing and level. The parameters provided are included in the model that includes the key keywords obtained (KH), average rating (AS), global standard (GR), wrap rate (BR) and daily page views per visitor (DPVPV). Thereafter a quality matrix is produced based on the quality of the extracted material. Pair pairing analysis was performed to determine the interaction between websites using scores on a quality matrix. The University of Kent (KENT) has been found
to have very high standards (13212.43) and in terms of quality content

The role of converters play a vital role in improving power production in renewable energy resource. As per the above aspects, the processing of various converters withappropriate control topology will help to convert low magnitude into higher voltage voltage range us mandatory. In accordance with gaining of higher magnitude, differential converter topologies are handled in this proposed work.There are numerous converters avaliable in nature. But depending upon the voltage requirement the converters are chosen. So that the topologies handling in proposed topology are cuk, SEPIC, zeta, and landsman converter. To resolve switching stress a proper gate triggering portion is essential. Thus FUZZY logic control system is preferred due to its advantages like robust in nature, able to handle non-linearities,and able to work witofvague input voltage to attain finite output. To concern high voltage and satisfies load requirement the fuzzy controller is interfaced with above mentioned converter to examine which one is perfect with low switching stress and deducing harmonics is essential one in this analysis. The experimental analysis is carried out with low voltage range to determine the performance of individual converters are examined.

Ameloblastoma is one of the most common clinically significant tumor. It belongs to 1% of all oral tumors. Compared to maxilla, the mandible is qyite commonly affected (4:1). It affects both male and female population equally. The age at presentation is usually between 3rd and 7th decade of life. The usual clinical presentation is that of a slow growing asymptomatic intraoral swelling. There are four clinico-radiographic types of Ameloblastoma namely Unicystic, Multicystic, Peripheral (extra-osseous) and Desmoplastic. The Histologic types include Follicular, Plexiform, Acanthomatous, Granular, Basal cell & Desmoplastic. The unicystic type has three histologic variants namely luminal, intra-luminal and mural. This article is aimed at documenting three case reports of Ameloblastoma with histopathologic variations and correlating them with clinico-radiographic findings

Introduction: Smoking is an adverse behavior for one person and others. Although there are various negative effects of smoking, it does not affect the smokers to quit smoking, thus they had a nicotine dependence. The purpose of this research was to identify the sociodemographic characteristics and smoking history with nicotine dependence, and to identify the level of nicotine dependence on smokers.
Patients and Methods: This research was quantitative descriptive research. The population in this study was 338 smokers. This research used total sampling method and it obtained a sample of 159 adult respondents. Data were collected using the Fagerström Nicotine Dependence (FTND).
Results: The result of this research showed that, even though respondents in low levels of nicotine dependence (42,1%), most respondents were in a moderate level of nicotine dependence (39%), high of nicotine dependence (13,8%), and very high of nicotine dependence (5,1%). In addition, the majority of nicotine dependence tended to occur in respondents aged 18-40 years (49,7%), male (84,3%), final year of high school (49,1%), working as an entrepreneur (65,4%), and had an income of less than Rp2.893.074,72 (68,6%). In respondents’ smoking history, nicotine dependence was more likely to occur in respondents who started smoking at the age of 13-17 years (50,3%) with smoking for 1-10 years (30,2%), and smoking clove cigarettes (52,8%).
Conclusions and Recommendations: The conclusion of this study that most respondents were in low levels of nicotine dependence and some respondents were in moderate, high, and very high levels of nicotine dependence, and there was a tendency between income and nicotine dependence.

From years to years, the smoking behavior of teenagers in Indonesia seems to keep increasing. There are also various types of cigarette being consumed, the most popular of which are, beside conventional cigarettes, electronic cigarettes. This research aims at expounding the perception of conventional and electronic cigarettes on teenage students in on Sumedang Regency, West Java, Indonesia. The research method is quantitative-descriptive, involving 365 students using stratified cluster sampling. The research result shows that most teenagers have a high positive perception on the impact of conventional cigarettes (65.2%) and electronic cigarettes (59.8%). The tendency of respondents who have a high perception on the impact of conventional and electronic cigarettes are in grade X (tenth), are female, have a daily allowance, and are not smokers, both of conventional and electronic cigarettes.

To get rapid and sustainable development, harmoniously solving the relationship between economic growth and environmental protection, “no trade – offs” economic growth with environmental pollution and degradation, transition to a circular economy is the appropriate direction. However, this transition needs to catch up opportunities and accept the challenges that need to be overcome. Global economic growth has gained great achievements, along with that is the shortage of natural resources, the increase of environmental pollution. However, the circular economy also requires strict conditions in terms of institutions and resources. Therefore, the study of the experiences of the preceding countries, points out the difficulties and advantages, and then shines on Vietnam, identifying conditions for the transition from a linear economy to a circular economy is the main content that the Southeast region's economy is aiming for

It is not common to diagnose a medical condition as another condition based on clinical features and investigations which later turns out to be normal because of a congenital lesion. There are many lesions reported mimicking Diaphragmatic Hernia which were treated or found during when operated for the other diagnosis. Here we report a case of Pleural effusion on the left side which was treated as Tuberculosis pleural effusion later which was found to be a congenital Diaphragmatic hernia in a middle age male.

There are various approaches to the classification of ergogenic agents used to improve the physical capabilities of athletes. Mainly, ergogenic agents of five different classes are considered: food, physiological, psychological, pharmacological, mechanical. This article analyzes the results of recent scientific publications concerning the use of physiological ergogenic agents by highly qualified athletes. The study showed that the use of a hyperoxic gas mixture has a directed effect on the functional capabilities of the cardiorespiratory system, optimizing vegetative support. The use of oxygen support before maximum exercise helps to increase the performance of the oxygen transport system, the overall performance of the heart, as well as reduce the limiting capabilities of the respiratory system. Breathing a hyperoxic gas mixture for 20 minutes after maximum exercise accelerates the processes of urgent recovery of the cardiovascular and respiratory systems.

Dengue Hemorrhagic Fever (DHF) risks causing death when the sufferer experiences shock due to bleeding. Until now, there is no specific drug to cure DHF. This study was aimed to determine the effect of interpersonal communication on improving the prevention of Dengue Fever (DHF). The type of research used is Quasi-experiment with nonrandomized pretest-posttest control group design. Samples were taken by simple random sampling of 78 respondents from a population of 1,791 households each of 39 respondents in the intervention group and 39 in the control group. Data collection uses questionnaires and interviews in the working area of the Baubau City Meo-Meo Community Health Center. Data were analyzed using the Wilcoxon and Man Whitney tests. The results showed the percentage of respondents characteristics in this study the most age groups were 28-38 years 39.74%, female sex 79.48%, married 92.31%, high school education 56.41%. The mean score increased knowledge (13.21 to 17.49), AND attitudes (33.38 to 38.92) about DHF before and after interpersonal communication. The mean score increased knowledge (12.69 to 16.49), and attitudes (33.33 to 37.46) about DHF before and after counseling. While the comparison of the intervention group was significant from the control group with (p <0.05) namely knowledge (p = 0,000), and attitude (p = 0.021) about DHF. Interpersonal communication is more influential than counseling and the need for monitoring and evaluating the implementation of interpersonal communication on an ongoing basis.

The objective of this research was to determine the effect of principal’s leadership, and job satisfaction to performance of guidance and counseling teachers at Public Vocational School in Jakarta, Indonesia. The research was conducted by using a survey method with path analysis applied in testing hypothesis. The research method is used quantitative approach, using path analysis. The target population size of this research is 133 of teachers. Research samples selected as much as 100 teachers using simple random sampling technique. Results of this study indicates that the principal's leadership and teachers’ job satisfaction have a very important role on the performance among guidance and counseling teachers.The implication of the research is that it is crucial to strengthen teachers' job satisfaction in order to improve the performance among guidance and counseling teachers. Based on this research of data obtained the following conclusions: (1) the principal’s leadership has positive direct effect on performance, (2) job satisfaction has positive direct effect on performance, (3) the principal’s leadership has positive direct effect on job satisfaction. The conclusion is that the teacher’s performance is effected by the principal’s leadership, and teacher’s job satisfaction.

Introduction:
Disabilities are nuanced and multifaceted; 15% of the world's population is disabled and has trouble working. Deaf and dumb cause major lifestyle changes and habits among adolescent girls that lead to physical, psychological, and social adjustment issues. Menstruation is a normal physiological process every teenage girl experiences every month. The ability to manage menstruation hygienically is essential to the dignity and wellbeing of women, which is an integral part of basic hygiene, sanitation and reproductive health services. Objective: To determine the existing knowledge and practice of menstrual hygiene among specially abled adolescent girls at selected centres in Bhubaneswar(BBSR). Methods: This cross-sectional study was conducted between September 2020 and November 2020 in Bhubaneswar town of Odisha. Total census sample of 22 deaf and mute adolescent girls from B.B.C Govt High School for the Deaf (Unit III), Bhubaneswar. A questionnaire consisting of three parts namely Part A: Sociodemographic and obstetrical and gynaecological information; Part B: Menstrual hygiene knowledge questionnaire; and Part C: Menstrual hygiene practice checklist. Results:The finding of the study reported that 45.46 per cent had moderately adequate knowledge on menstrual hygiene; 27 per cent of study participants had proportionately inadequate and adequate knowledge of menstrual hygiene, and 86.37 per cent had reported good practice in menstrual hygiene.The Mean and SD of Knowledge score was 37.958 ,Practice was 8.50 and Karl Pearson Correlation (r =0.26, p=0.23) estimated that there was no significant positive fair correlation between knowledge score and practice score. Conclusion: Good menstrual hygiene triggers women's health, trust and self-esteem and is linked to gender equality and fundamental human rights. Setting realistic time-limited targets, including education (Videos and Information Booklets) on hygienic practices followed during menstruation using sign language for deaf and mute adolescent girls, would be a welcome effort to provide basic hygiene and reproductive services to specially-enabled girls and women.

Health care waste is one of the ascended and emerged issues all over the world today. It not only affected people also the environment, animals, and crops. Protection from Health care waste is still a threat for Sri Lanka due to the amount of total generation of clinical waste and the availability of the treatment/disposal hence needed drastic technological improvements. This study aims to identify the impact of the current disposal management process in Health Care Waste Management (HCWM) of selected hospitals in Kalmunai Medical Officer of Health Division, Sri Lanka, along with the development of a software prototype for effective data management and decision making, using agile methodology, accommodating most functionalities. The output of the prototype witnesses proper data management. OLS method used to examine the relationship between Health Care Wastes (HCW) Procedure impacts on HCWM; the regression results show that except for other variables, the Segregation of HCW and Waste treatment & disposal have a negative relationship with the HCWM. These negative relationships highly recommended a need for a software system for making important decisions regarding the Health care waste procedure to have a standardized Health care waste management system sheltering Whole Island with sustainable solutions.

Agricultural Landuse plays a vital role in the entire environment of the Nagaon district. Comprising of 3993 sq.km. of geographical area, the district reflects the spatio-temporal variations in agricultural landuse. In course of time the growing population stresses upon the agricultural landuse pattern of the district for fulfilling their various requirements like residence and day-to-day activities of livelihood. This interference of population and changing agricultural landuse effects the environment and the biotic ecosystem of the district, where man-animal conflict is also a common fact in some parts of the district. To achieve environmental sustainabilty, adoption of sustainable agriculture practices and enhancing agriculture productivity is highly needed.
This paper examines the changing trends of agricultural landuse of Nagaon district of Assam .The attempt is to reflect the agricultural landuse change dynamics occurred due to various natural and man-made factors.
For preparation of this paper, primary data are collected through questionnaires and personal visits with the local people in the field. Secondary data are collected from Govt. offices and websites

Movement against CAB (CAA) brought the struggles I Assamese people to light in front of the world. This movement creates a new chapter of Assamese people’s love for their own land, Culture, tradition and language which can’t be ignore by the history of India in future.This is a movement to stop the foreigners to enter Assam (India). But during that time of movement some castes and tribes of Assam were involved themselves in a different way. It means, even though the movement against CAA was about fighting against the government’s decision of giving citizenship to foreigners, but some castes and tribes of Assam completely ignored the main motive and started to demand constitutional safeguard for themselves under the clause 6 of Assam accord. In this article, We will try to analyse the roles of these people in this movement and how their motive has changed the whole political scenario during the time of movement against CAB(CAA) in Assam.

Purpose: Afghanistan has been in the spotlight for civil war and innocent sufferings belonging to various ethnicities. The purpose of the essay is to investigate how racial or ethnic identity provide the space for discrimination, oppression and exclusion on the special reference to The Kite Runner(2003) and A Thousand Splendid Suns(2007)
Methodology: The paper usesdescriptive research by applying racial theories of prominent theorist on Khaled Hosseini’s writings to critically analyse the texts.
Main Findings:The plight of the minorities—Hazaras and women are doubly marginalised whose root cause is ethnic discrimination against them. This bigotry is nothing but a social construct.The paper discusses the exclusion and its paraphernalia on marginalised minorities can be belittled by nullifying foreground formation of hegemonial ideology at structural level in society.
Applications: Discrimination based on race and colour is found at each level even in the developed nations.This research can be useful for all third world or developing nations where the ethnic discrimination is practised.
Novelty/Originality:In this essay, the discrimination, double marginalisation of Afghan minorities is presented in a comprehensive manner.

The cancer survival journey starts for the person at the time of diagnosis and lasts until the end of life, with adverse effects on normal activities. Breast cancer mortality is strongly associated with poor sleep. Fatigation and decreased appetite are the hallmarks of cachexia in terminally ill patients. Inadequate medication adherence may cause alterations in risk-benefit ratios. Aim: To assess the sleep quality , fatigue, and medication adherence among breast cancer survivors and to find their association with the selected demographic variables. Methods: This was a descriptive cross-sectional analysis involving 60 samples of OPD medical oncology using a convenient sampling technique and the study duration was one week. Pittsburgh sleep quality index scale, Perform questionnaire, Medication adherence rating scale were used to assess the patients. RESULTS: The study concluded that 61.67% of the cancer survivors were disordered sleepers, 45.00% of the cancer survivors were having low fatigue score and 71.67% of the breast cancer survivors were having good medication adherence score. There was a strong positive equal correlation between the Sleep Quality Index score and the Fatigue score, which indicates that the quality of sleep raises the fatigue score. CONCLUSION: Clients suffering with breast cancer should be assessed for sleep quality, which directly helps to reduce the fatigue level. Evidence-based practice interventions like Exercises, cognitive behavior therapy, yoga, and aerobic exercises could help the patient to have adequate sleep.

Background: Chronic kidney disease (CKD) is an independent risk factor and caused high morbidity and mortality for coronary artery disease (CAD). Several scoring systems can be used in assessing the severity of CAD, one of which is using the SYNTAX score (SXscore). Smoking is one of the risk factors for the progression of CAD and CKD. Several observational studies have under-reported the smoking factor influencing the rela-tionship between eGFR and SXscore.
Methods: This research is an observational study with a cross-sectional approach conduct-ed at the Wahidin Sudirohusodo Hospital Makassar from July-August 2020. This study involved 62 CAD and CKD patients undergoing angiography. The estimated glomerular filtration rate was based on chronic kidney disease epidemiology collaboration (CKD-EPI).
Coronary angiography results were converted to SXscore and smoking grade based on the Brinkman index.
Results: This study involved 62 CAD and CKD patients male (71%), aged ≥ 55 years (77.4%), hypertension (71%), diabetes (35.5%), smoking (50%), eGFR G3a & G3b (53.9. %) and SXscore medium-high (50%). The results showed that lower eGFR could increase the SXscore (p < 0.001), especially in smoking subjects (p < 0.001). Multivariate analysis showed that gender was the most significant factor contributing to the relationship between eGFR and SXscore
Conclusion : The lower eGFR could increase the SXscore, where this correlation was more significant in smoking patients. Multivariate analysis showed that gender was the most significant factor contributing to the relationship between eGFR and SXscore.

Healthcare workers need to contribute to good hospital governance. This research aimed to elaborate on the role of pharmacists to establish good hospital governance following Indonesian regulations.This is normative research. Data were collected through a literature search using “google machine” with “good hospital governance,” “pharmacists’ role in the hospital,” “pharmacists’ regulations” as keywords. Collected raw data were reduced to the most relevant data by conducting a content analysis. The applicable data were then analyzed using a qualitative method to answer the purpose of the research.Good hospital governance needs proper corporate management and good clinical governance. Findings proved that there were not many provisions in the regulations that govern the role of pharmacists in the hospital. However, those provisions were sufficient enough to justify the role of pharmacists in “creating” and maintaining good hospital governance. Pharmacists have two essential but different side by side roles in the right hospital governance settings.

In this study, the preparation of hydroxyapatite nanoparticles (HA NPs) from eggshells were carried out using chitosan nanoparticles (CS NPs) for the incorporation of urea fertilizers. The interaction and stability of HA NP/CS NP suspensions containing urea fertilizer were evaluated by FTIR spectroscopy, X-Ray diffraction (XRD), particle size and shape analysis by transmission electron microscopy (TEM) and composition by EDX. The synthesized HA NPs/CS NPs and HA NPs/CS NPs loaded with urea fertilizer after dissolved in water for 6 h with sizes as small as respective ~30-55 nm and ~50-90 nm were achieved. The obtained nanoparticles had a homogeneous morphology showing a quite uniform particles size distribution with a spherical shape. The mean diameter increase of the HA NPs/CS NPs in suspension with the addition of urea indicated that the elements are being aggregated and loaded on the surface of urea fertilizers.

In every century, few invisible infectious diseases create an alarm to the entire world and which leads to extermination of the population. In 1918 and 2019, the world has tackled truculent diseases such as mother of all pandemic Spanish flu and COVID 19. The mortality rate of Spanish flu was greater than in the first world war. After 100 years’ same history was repeated in 2019 through COVID 19.  Suddenly a huge number of pneumonia cases were reported in the end of 2019 in Wuhan, China. These two outbreaks make medical, social and financial burden to the entire world. This kind of sudden pandemic breaks mental health and creates panic, anxiety and depression. Pharmaceutical preventive measures are not supported during both pandemics which was rectified by non-pharmaceutical preventive steps like lockdown, quarantine, wearing facemask and gloves, washing hands and applying sanitizer, follow the social distancing, closing cinema hall and schools, avoiding mass gathering in 1918and 2019-2020. The main objective of this review is to compare and summarize the concepts of both pandemics and how the people of the world need to come together and fight against common enemies, to warrant that we have the best scientific resources necessary to bring this outbreak to an end.

Background: To determine the profile of vitamin D and interleukin-8 (IL-8) in COPD exacerbation.
Method: This research is an analytical study with a cross-sectional approach conducted at the Wahidin Sudirohusodo Hospital Makassar from March-June 2020. Serum levels of vitamin D (25-hydroxyvitamin D) and IL-8 were measured using the ELISA method in 65 exacerbated COPD patients based on clinical examination, chest radiograph, & spirome-try. The exacerbation criteria were based on Anthonisen and divided into two groups ac-cording to the exacerbation frequency in the past year (frequent exacerbations was often ≥ 3 times/year, infrequent exacerbation < 3 times/year) and related to gender, age, nutrition-al status, smoking status based on the Brinkman index, and obstruction degree according to the Global Initiative for Obstructive Lung Disease (GOLD) 2019.
Results: This study consisted of 65 exacerbated COPD subjects (62 men, 95.4%), with age of ≥ 60 years 73.8%, frequent exacerbations of ≥ 3 times/year, 69.3%, vitamin D deficiency status of 76.9 %, and it was found to be significantly lower (15.1 ng/ml) at the frequent ex-acerbations of ≥ 3 times/year (P <0.01). The means of IL-8 levels were 187.48 +68.30 ng/L and found to be significantly higher (206.7 ng/L) in the frequent exacerbations ≥ 3 times/year (P <0.01). In all subgroups according to gender, age, nutritional status, smok-ing status, and obstruction degree, there was a tendency for the lowest vitamin D and higher IL-8 in the frequent exacerbations of ≥3times/year. Conclusion: Vitamin D levels were found to be the lowest and IL-8 was higher in COPD patients with frequent exacerbations of ≥ 3 times/year, compared to those with the infre-quent exacerbations of < 3 times/year.

Background:Incidence of pulmonary TB in type-2 diabetes mellitus patients is still high. Gender, age, nutritional status, duration of diabetes, blood glucose control, smoking habit, and HbA1c, are among risk factors that influence its occurrence. This study aims to analyze the risk factors that contribute to the incidence of pulmonary TB in type-2 DM patients in Makassar.
Methods:A survey analysis study at Wahidin Sudirohusodo Hospital. Hasanuddin University Hospital. and educational network hospital.on December 2019 until the desired sample reached. Sample collection using consecutive sampling. Data analysis using SPSS verse 22. Statistical analysis using pearson’s correlation. chi square test. and multiple logistic regression (backward method). Significant result if p value <0.05.
Results:Study included 225 type-2 DM patients. From study shows distribution of pulmonary TB in type-2 DM patients is 13.3%. Incidence of pulmonary TB was high in patient with underweight (OR=6.7 and p<0.05), duration of DM>5 years (OR=3.8 and p<0.05), and uncontrolled blood glucose (OR=2.7 and p<0.05). There was no significant correlation between gender (female 19 from 135, male 11 from 90 with p>0.05), age (age >60yo 15 from 92, age ≤60yo 15 from 133 with p>0.05), smoking habit (yes 10 from 84, no 20 from 141 with p>0.05) and HbA1c (A1c <7 was 0 from 7 and A1c ≥7 was 30 from 165 with p>0.05) with pulmonary TB incidence.
Discussions:Incidence pulmonary TB in type-2 DM patients according to BMI was significant (p<0.05) because condition of malnutrition can lowering the immune status by decreased the limphocytes production and immune proliferation also decreased of IFN-gamma and IL-2 level, and increased of TGF-beta. Incidence according to duration of DM was significant (p<0.05). Incidence according to blood glucose control was significant (p<0.05), DM and uncontrolled blood glucose can lead to an immune compromise condition, some of risk factors that also can contribute to infection disease.
Conclusion:There was significant correlation between underweight, duration of DM >5 years, and uncontrolled blood glucose with pulmonary TB incidence.

Background of the Study: Bacterial and Viral infections are often hard to be distinguished in daily clinical practice. Biological markers obtained from a routine examination play an important role to minimize time in providing diagnose and giving therapy. Recently, the use of Neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), and platelet-lymphocyte ratio (PLR) is greatly considered to differentiate types of infection found in the patients presenting with fever.
Method: This study uses prospective cohort study design and involves patients presenting with fever who are admitted to the ICU. The initial NLR, MLR, and PLR is examined and categorized into types of infection found. The ANOVA test and t-test are performed to find out the difference among study groups with the value of α = 0,05.
Result : This study involves 207 patients (92 male patients [44%]) presenting with fever with the average age of 45,6 ± 14,6 years old. The majority of cases (135 cases [66,5%]) in patients with fever results from bacterial infection; The study also finds 47 cases (34,8%) of typhoid fever and 30 cases (22,2%) of pulmonary tuberculosis. Dengue hemorrhagic fever (DHF) is the most commonly found viral infection with 52 cases (76,4%). The significant diagnose of bacterial infection shows higher value of NLR and MLR than that of viral infection (P < 0,001); Urinary tract infection has the highest value of NLR and MLR, amounting to 9,4 ± 3,6 and 0,23 ± 0,20, respectively. In general, the value of PLR is lower than that of viral infection (P < 0,001).
Conclusion: Neutrophil-lymphocyte ratio, MLR and PLR have benefit to predict diagnosis for the patients presenting with a fever. Bacterial infection is associated with the high value of NLR and MLR, and PLR generally has a lower value in viral infection cases.

State of neurological disorders patients evaluated by the Glasgow Outcome Scale extended. Thus, it may be noted positive clinical and neurological changes of patients who were treated according to our suggested methods – endolumbar introductions of nootropic ozone mixture and endocystal introductions of ozone.

Diabetes mellitus has the most significant effect on the state of the oral cavity. Therefore, pediatric dentists should be aware of the characteristics of the course of oral diseases in children with diabetes [Nirmala SVSG, Saikrishna D, 2016, Babu SR, Eisenbarth GS., 2012]. Diabetes mellitus is a multifactorial disease characterized by a chronic rise in blood glucose levels or hyperglycemia and is caused by impaired insulin secretion and / or insulin dysfunction. Diabetes is also called a silent epidemic and a majora public health problem and accounts for 9% of all deaths worldwide [Nazir MA, Al Ghamdi L, Al Kadi M, Al Beajan N, Al Rashoudi L, Al Hussan M., 2018]. The accumulated scientific knowledge on the study of the biochemical and immunological composition of saliva in various chronic pathologies, including diseases of the gastrointestinal tract , stress, have shown the ability of the secretion of the oral cavity to reflect the processes occurring in the patient's body, and serve as an adequate substrate for monitoring homeostasis [Komarova L.G., Alekseeva O.P., 2016]. According to the Action Strategy for five priority areas of development of the Republic of Uzbekistan in 2017-2021, important tasks have been identified in order to ensure a full life for vulnerable segments of the population to improve the system of social protection of the population and health care, including, "increasing the availability and quality of medical and socio-medical services the population, the formation of a healthy lifestyle of the population.

Dental caries is the most common chronic disease among the child population. Caries of milk teeth takes a special place in the structure of this pathology. Despite the improvement in the quality and expansion of the volume of preventive and therapeutic measures, the level of intensity and severity of early childhood caries in our country and the Perm region in particular remains at a very high level. There are more than a hundred reasons contributing to the development of carious process in milk teeth. Of these, the most important are socio-demographic, biological, dietary, hygienic and factors related to the type of feeding. In this case, the consolidation or weakening of the action of such in a number of circumstances will determine the emergence and further development of early childhood caries [69, 103]. In the classical sense, dental caries is a chronic infectious disease induced by a violation of diet.

There are publications in the literature on the prevalence of tuberculosis and associated diseases, as well as surgical care for patients with tuberculosis with urological pathology. The clinic of tuberculosis and the effectiveness of its treatment, including pulmonary tuberculosis, is largely determined by the presence of intercurrent diseases that aggravate a specific process and complicate its treatment. The prevalence of attendant pathology in patients with pulmonary tuberculosis ranges from 80% to 100% [1; 2; 3]. Thus, the indications for surgical curing of urological diseases in patients with tuberculosis do not differ from those in the absence of tuberculosis. Absence or insufficient duration of anti-tuberculosis chemotherapy is an absolute contraindication on the part of a specific process [4]. The study of the dispersion of urological diseases and its nature, especially in patients with tuberculosis in some regions, such as Bukhara region, located in the arid zone, showed a large proportion. Thus, urological pathology was detected up to 35.5% of the examined patients with tuberculosis, and designation of ICD was observed in 5.5% of those identified with urological pathology in the Bukhara region [5]. As preliminary data has shown, the elaboration of existing, the search for new, effective forms and methods of treatment and prevention of urological diseases, including in patients with tuberculosis, is of particular significance due to the need to amend the quality of life and reduce disability.

Capparis Spinosa L. is a medicinal plant and is used in the treatment of various diseases from canned products prepared in combination with its processed fruit buds, processed fruits and other ingredients considered dietary. The technology of dietary canned food made on the basis of caper fruit, which has therapeutic and prophylactic properties, has been developed, the chemical composition has been determined, and safety has been ensured. On the basis of theoretical studies, regimes of complete killing of microorganisms that spoil the caper and make it unfit for consumption have been found, optimal parameters of the sterilization process have been recommended. The optimal technology of canning capers is proposed.

Purpose: to assess the effect of Rh immunization on the state of indicators of innate humoral immunity in the fetus, such as immunoglobulins A, M, G, circulating immune complexes of large and small quantities, cytokines IL-1β and IL-8, which play a decisive role in the pathogenesis of the development of a pathological process ... Materials and Methods: Immunological studies were carried out on 17 umbilical cord blood sera from fetuses with hemolytic disease, which were taken by transabdominal cordocentesis in pregnant women between 24 and 33 weeks of gestation with Rh immunization at the Republican Perinatal Center for 2019 and 2020. All studies were carried out in the laboratory of

Abnormal spinal trauma is the most severe damage to the human musculoskeletal system and is found in the 2.3 -4.7% of cases [3, 7, 8]. The lethality of these injuries is up to 25-30% [7, 9, 10], and disability when it reaches up to 86-94% [(2, 7, 8]. In much of the results of treatment depend on the quality of medical aid in acute period of complicated spinal injuries in such cases, the purpose of early and effective treatment of these patients is not only the restoration of the basic function of the spine, but also the development of mechanisms of compensation broken spinal cord functions. Therefore, timely and efficiently provided medical care in specialized institutions significantly improves outcomes of injuries and enhances the quality of life of the victims.
In the last few years to treat complicated injuries of the spine, along with surgical method uses different medications that can help improve metabolism and blood circulation, reduce edema and medications for the injured area of the spinal cord.
So far, have been widely used corticosteroid medications (dexamethasone and methylprednisolone) in acute period of injury. Use of steroid hormones improves metabolism in acute period of spinal cord injury. Corticosteroids also provide stabilizing membranes, reduces edema, "clean" acid radicals, reduce metabolism products contribute to cerebrospinal fluid diffusion of oxygen into the fabric. But the drugs have significant side effects, as well as a number of reasons.
Now continue to search for drugs and methods aimed at correlation metabolic violations in the spinal cord, resulting in hypoxia and to improve treatment outcomes.

In the conditions of the steppe zone of the Samarkand region, 5 local ancient varieties of spring soft wheat of various geographical origin were studied. The aim of the research is to evaluate the grain quality indicators of ancient wheat varieties in various meteorological conditions and to identify sources of protein and gluten content for use in practical breeding.
The negative effect of abundant moisture (26%) during the filling period and high air temperature (26%) in the phase of grain ripeness on the quantity and quality of gluten was found. It is shown that the studied ancient varieties in typical meteorological conditions of the steppe zone of the Samarkand region stably form first-class grain: the maximum protein content in the grain is 13.1-14.5%, raw gluten-33.2-35.4%, the number of drops-319-340 s, nature-758-779 g/l. At the same time, the potential of rheological properties of the dough in varieties exceeds the norms for strong wheat: dough liquefaction-39 u. f., valor metric assessment-60-72 u. V. calorimeters.
The volume of bread-678-773 ml with a total score of 3.0-4.8 points. Studies have shown that the meteorological conditions of the year cause a high phenotypic variability of the rheological properties of the dough (CV=51.4-64.3 %), the average variability of signs: the number of falls (CV=12.2-14.0%), the mass fraction of protein (CV=9.1-12.2 %, the overall score of bread (CV=8.1-11.3 %). On the basis of the conducted research, the source varieties for indicators of technological properties of grain for use in practical breeding programs are identified.

In the overall structure of spinal injuries in adults vertebro-spinal injury ranges from 2.2% to 20.6% [2,5,7,8,10,12,22]. When fractures of the spine are complicated by neurological disorders, most commonly lower thoracic and lumbar vertebrae - 39.2% and 48.5% are injured respectively [2,4,12,15].
According to various authors, the greatest proportion of spinal injuries is accounted for cervical - 30,0-40,0% of cases, followed by lumbosacral - 25,0-45,0%, thoracic - 15,0-25,0% and multilevel spinal injuries - about 5% [3,4,5,7,12,13,15,16,22,24,26].

Thetechnology of engineering science is growingfaster and its usage isto bootincreasing speedily. The data and its usage has become an important issue in existence. There by the storage of data may be a crucial issue in means of life. For this data storage, Cloud Computing is useful. Cloud computing is that the follow of using a network of remote servers hosted on internet to store, manage and methodology data on demand and pay as per use. It provides access to a pool of shared resources instead of native servers or personal computers. as a result, outfit do not acquire the things physically, it saves managing value and time for organizations. As a result of the sector of cloud computing is spreading the new techniques are developing. This increase in cloud computing setting to boot can increase security challenges for cloud developers. Most of the organizations are an excellent deal concerned regarding the possession of their data.This analysis paper presents a review on the cloud computing concepts yet as security issues inherent at intervals the context of cloud computing and cloud infrastructure. This paper in addition analyses the key analysis and challenges that presents in cloud computing and offers best practices to service suppliers yet as enterprises. The foremost goal is to review different types of attacks and encryption techniques to secure the cloudmodel.

Vehicular Ad Hoc Network (VANET) is a type of Mobile Ad-Hoc Network or MANET which gives correspondence among vehicles and among vehicles and street side base stations. A vehicle in VANET is viewed as a savvy portable hub fit for speaking with its neighbors and different vehicles in the system. VANET is unique in relation to MANET because of high portability of hubs and the huge size of systems. Secure transmission and protection of data are the important constraint for structuring a VANET. Since there are many proposed work for improving protections in VANET, however secure transmission despite everything stays a sensitive research field. The primary destination of our work is to enhance the security concerns in vehicular networks. The fundamental endeavors were centered on the potential applications, potential assaults, secure prerequisites and the writing perusal. The long haul objective of this venture is to concoct an altogether new arrangement that can be executed in structuring a vehicular network.

Enhancement of contrast in an image is a vital process of image processing, it increases the intensity of image pixels. By enhancing the contrast of an image, the quality of the image will be increased.The anticipatedtechniqueis the combination of non-subsampled contourlet transform and bilateral filter. The key contribution of this paper is the usage of a weighted mean separated sub-histogram equalization technique for increasing the contrast of medical ultrasound images. The performance of the proposed technique provides improved contrast enhancement features when related with the existing methods such as contourlet transform and Histogram Equalization in terms of structural similarity index matrix, PSNR and Absolute Mean Brightness Error.

In Deep learning methods such as automatic encoder, long-term short-term memory (LSTM) and repetitive neural network (RNN), in mixed group of population, fasting blood glucose level (FBGL) was used to detect the BG level. The Indian population is healthy and sick. The appearance of high FBGL from the electrochemical parameters of human saliva, redox potential, pH, concentration of sodium, and calcium ions was evaluated. Samples were taken from 175 randomly particular persons, half of healthy patients and half of those with diabetes. Models were trained with 70% of all data and tested in the remaining set. In every algorithm, the data points were randomly crossed three times before the model was implemented. The effectiveness of machine learning techniques is presented in terms of the four parameters that are statistically significant, the accuracy, the sensitivity, and the F1 score. The proposed analysis shows that the RNN-based deep learning method yields better results. This deep learning technique to measure blood glucose level non-invasively using electrochemical saliva will helps the society to control the diabetes effectively.

Today, Identification of good quality seeds or crops is a major challenge in India. It is sort out using Image Classification and Data Mining techniques. Picture classification is a favoured strategy for horticulture item identification since the item is unblemished from the cycle. The image is captured and the features are distracted based on their attributes. This is then clustered using K-means and Principal Component Analysis method to assign the grades based on the result.

Cloud Computing is the network-based computing service to the user supported by internet. The computing service may be a data storage, hardware, software or any internet-based service required for an individual user or a business organisation. The cloud services are On-demand services available to the users at anytime and anywhere. The Cloud Service provider is responsible for monitoring data, firewalls, intrusion detection management and other security concerns while providing cloud-based services to the end users. There are many challenges in selecting trusted cloud service. Many Cloud Service Selection Procedures are there which are based on data Models, decision making procedures, context and parameters of cloud services. In this paper, proposed a trusted Cloud service based on score based algorithm.

Self-compacting concrete is a stream sort of solid that spreads into the structure without the requirement for mechanical vibration. Self-compacting concrete is a non-isolating solid that is put by methods for its own weight. The measure of steel fiber in SCC has 0.3%, 0.6%, 0.9%, 1.2% and the steel fiber length has 30mm and 0.5diameter.To increment the functionality of cement the super plasticizer can be included. In this paper the solid throwing by utilizing the 3D square and new solid test should be possible .To recognize the solid quality the pressure quality should be possible in 7 days and 28 days

Accident count is increasing day by day. Fog is one of the main causes of accidents, especially in hilly regions. As fog density increases, visibility of the road gets decreased. The drivers will not be able to see the road or any obstacle that is present. Unfortunately, few people do not slow down their vehicle even in the worst fog environment. So we are proposing a system that detects a foggy environment and reduces the acceleration of the vehicle, to avoid accidents. In the proposed system, a sensor that is directly connected to Arduino Uno is used to automatically calculate the values of temperature and relative humidity from the atmosphere. Based upon the values of dew point, the speed of the vehicle is controlled. If the Dew value is less than 2.5°C it indicates the presence of fog. Depending upon the Dew Value the complete control takes place. Also, from Arduino the data is sent to cloud through IOT module and from there we can access in App.

The autonomous car is the vehicle that is capable of sensing its environment and can navigate without any human input. In this vehicle we use GPS for navigation and the ultrasonic sensor to avoid collisions. Since it is autonomous, the threat of stealing the vehicle will be more. In order to keep it secure, the GSM and GPS modules are provided with key. If anyone tries to unlock the vehicle apart from the normal procedure, by using the GSM module the message will be sent to the owner of the vehicle. GPS is used to locate the exact latitude and the longitude position of the vehicle. If the owner replies back to the GSM module that the vehicle is in theft, the engine gets locked automatically. The Ultrasonic Sensor is used to detect the obstacles and also for the determination of the distance with high accuracy. So, the vehicle will be able to sense the fore coming vehicle or the obstacle and will get alert. In order to focus the headlights of the car in the direction of the turn, i.e. in the direction of wheels, the servo motors are used. The Servo Motors allows the control of the angle, velocity and the acceleration. The Servo Motors takes the angle of the wheel during the change of direction. By making use of that angle, the headlights will rotate along the direction of wheels. The solar panels are used to absorb the radiations that are emitted by the sun. These absorbed radiations are converted into Electrical Energy which is used to charge the batteries. An Arduino Port is used to interconnect all these equipment’s to work according to their applications in an effective manner. The directions of the vehicle in which it is moving and the detection of the obstacle will be displayed on the LCD. Finally, when the predefined path is reached, the alarm starts ringing to confirm that the destination has been reached.

Fractures of crown and root are common emergencies encountered in the dental office. Root fractures are defined as fractures involving the dentin, cementum and pulp. These root fractures are broadly classified as horizontal/transverse and vertical root fractures. The correct diagnosis is essential to ensure proper treatment of root fractures. Various treatment strategies have been proposed, each has its own advantages and disadvantages. Hence this review article presents an overview of various types of root fracture, their diagnosis and clinical management

With the greater worldwide availability of neuroimaging, more arachnoid cysts are being found in all age groups. A subset of these lesions become symptomatic and requires neurosurgical management. The clinical presentations of arachnoid cyst vary from asymptomatic to extremely symptomatic.[1]
Arachnoid cysts are non-neoplastic, intracranial cerebrospinal fluid (CSF)-filled spaces lined with arachnoid membranes. Large arachnoid cysts are often symptomatic because they compress surrounding structures; therefore, they must be treated surgically. As several surgical management options exist, we explore the best approach according to each major type of arachnoid cyst: middle cranial fossa cyst, suprasellar cyst, intrahemispheric cyst, and quadrigeminal cyst. [2]
Arachnoid cysts are benign space-occupying brain lesions that contain cerebrospinal fluid. Most cases are congenital in origin, caused by failed fusion of the arachnoid membrane early in fetal development. Cases are often incidentally detected on neuroimaging; however, rarely patients present with neuropsychiatric manifestations when cysts expand and cause a midline shift, compression of nearby brain tissue or cerebrospinal fluid compartments or both. [3]

Sella turcica is a saddle shaped bony structure present on the sphenoid bone. The pituitary gland is seated at the inferior aspect of the sella turcica, called hypophyseal fossa. Sella turcica serves as a cephalometric landmark, that being said any morphological changes can affect the overall craniometry of the individual as well as alter the function of the structures it lodges. The following review emphasis on the possible morphological changes of sella turcica and its effects on the individual.

Iridology is defined as a photographic science that identifies pathological and functional changes within organs via biomicroscopic iris assessment for aberrant lines, spots, and discolourations. According to iridology, the iris does not reflect changes during anaesthesia, due to the drugs inhibitory effects on nerves impulses, and in cases of organ removal, it reflects the pre-surgical condition. The profession of Homoeopathy is frequently associated with iridology and in a recent survey (2009) investigating the perceptions of Masters of Technology graduates in Homoeopathy of University of Johannesburg, iridology was highly regarded as a potential additional skill requirement for assessing the health status of the patient. It is also known as iridodiagnosis or iridiagnosisis an alternative medicinetechnique whose proponents claim that patterns, colors, and other characteristics of the iriscan be examined to determine information about a patient's systemichealth. It is an analysis of health based on examination of the iris of the eye. Practitioners match their observations to iris charts, which divide the iris into zones that correspond to specific parts of the human body. Iridologists see the eyes as "windows" into the body's state of health.Iridologists claim they can use the charts to distinguish between healthy systems and organs in the body and those that are overactive, inflamed, or distressed. Iridologists claim this information demonstrates a patient's susceptibility towards certain illnesses, reflects past medical problems, or predicts later health problems.

The human upper airway is important in many voluntary and involuntary tasks such as swallowing, speech and breathing. The nasal, pharyngeal and laryngeal region forms upper airway. It is a complicated structure that plays a key role in breathing, vocalization and swallowing. The upper airway is a highly flexible structure that lack rigid bony support. It is vulnerable by pressures that are generated during inspiration and by the surrounding soft tissues. The focus in this article was on the genioglossus muscle and its role in maintaining upper airway.

Tay-Sachs disease (TSD) is a fatal genetic disorder that causes progressive destruction of the nervous system. It also affects the mental and physical abilities of that being around six month of age. TSD most commonly occurs in children that causes the slow destruction of the central nervous system.. It occurs when more quantities of cell membrane components called gangliosides, accumulate in the brain’s nerve cells. This occurs due to the absence of an important enzyme called Hexosaminidase-A (HEX-A).

Aim of this study was to investigate the growth inhibitory effect of Artemesis annua L. silver nanoparticles (A.annua AgNPS) on human triple negative breast cancer tumor cell line MDA-MB-231. Cells were cultured and treated with A.annua water extract and A.annua AgNPS to determine the half inhibitory concentration (IC50). Oxidative stress was determined using lipid peroxidation (LPO), ROS generation and by determining the levels of antioxidants, superoxide dismutase (SOD) and reduced glutathione (GSH). Further, the mechanism of apoptotic induction was assessed by DNA fragmentation analyses. We observed that A.annua AgNPS significantly caused growth inhibition by increasing levels of LPO and ROS, in a dose dependent manner with reduced level of endogenous antioxidant enzymes. Increased shear in genomic DNA from MDA MB231 cells treated with A.annua AgNPS shows apoptosis to be the cause of cell cell death. We conclude that A.annua AgNPS can be useed as a therapeutic agent against breast cancer.

The epidemiological relationship between nephrolithiasis and hypertension is well-known. Patients with hypertension are at increased risk for nephrolithiasis and those with nephrolithiasis are at risk for hypertension. An anomaly in RBC Oxalate transport and reduced activities of adenosine triphosphatases has been reported in patients with hypertension when compare to control subjects. This study presents an abnormal increase in transmembrane flux of oxalate in RBC of hypertensive subjects and it might be due to membrane degradation caused by oxalate-induced free radicals depleting erythrocyte thiol contents and impaired adenosine triphosphatases activity resulting in tissue injury and defective membrane transport. Thus relative risk of hypertension was significantly associated with increased oxalate flux rate and impaired adenosine triphosphatases activity in stone formers. This association is important when treating patients with nephrolithiasis since those with hypertension may require unique dietary and medical therapy.

Understanding the inhibitory mechanism of thymoquinone targeting proteins involved in lung cancer. Thymoquinone were reported as possible anti-cancer drug targeting the gene containing protein like GTPase KRas in the cancer inducing pathways and we have used molecular docking in order to understand the underlying mechanism. The target proteins were preferred from various studies in cancer inducing pathways were docked by thymoquinone and also with its analogue poloxime. Protein-ligand complexes were selected based on the binding energy ranked from lowest to highest according to thymoquinone. Our results identified that thymoquinone inhibiting GTPase KRas, Sir-2, ALK5 and β-Catenin,. The docking study also establishes the multifaceted role of thymoquinone as a chemo preventive anti-cancer agent against lung cancer. These in-silico study report would be the substantial platform for the drugs to be focused in future for in-vitro and in-vivo studies for exploring its multitude function for providing a functional strategy for using as a therapeutic agent against cancer.

The roasted forms of flaxseed and soybean were chosen for study as they are found to be enriched with phenolic components. They are also found to possess medicinal benefits particularly against non-communicable diseases like cancer. Hence the investigator analyzed the non-antioxidant enzymes and in vitro antioxidant activity of roasted soybean and flaxseed. After a deeper analysis, it was observed that flaxseed possessed greater anti-oxidant activity than soybean comparatively.

Over 100 years of decay, major populace focus on traditional plants for treating massive disease due to the presence of active component. Biologically active compounds present in the medicinal plants have always been of huge curiosity to scientists for focusing on exploring plant products. Nothapodytes foetida (also known as Mappia foetida or Nothapodytes nimmoniana) is an average size tree belonging to family Icacinaceae. It is distributed in Southern India, North India, Srilanka, Myanmar and Thailand. It is an imperative medicinal plant, the foremost source of a potent alkaloid, namely camptothecin, of a wide spectrum of pharmacological activities like anti-cancer, anti-HIV, anti-malarial, antibacterial, anti-oxidant, anti-inflammatory, anti-fungal and also applied in the treatment of anemia. This review article compresses about the phytochemical constituent, pharmacological activity of bioactive component of N.nimmoniana species of root, stem, leaves and bark of the plants.

From prehistoric era, the plants are used as a healing for many alarming disease due to the presence of therapeutic value. Even in contemporary invention, many herbal plants are intent in research field to concise about the efficacy of plant in curing disease with fewer side effects in long term exposure. Physalis minima Linn is generally used in the indigenous system of medicine for various diseases like diuretic, fevers, etc. In the present study, an attempt was made to evaluate the phytochemical substances and bioactive compound of the aqueous methanol extract of unripe fruit of Physalis minima Linn. The crude extract was separated by soxhlet using methanol as solvent followed by the phytochemical screening to identify the presence of secondary metabolites. Volatile components present in the methanol extract were separated and identified using GC/MS. The Gas chromatography - mass spectrometry chromatogram result showed the presence of total of 18 bioactive compounds in crude extract of physalis minima Linn which are exhibiting different biological functions such as antioxidant, anti-inflammation, anticancer, antidiuretics etc. Antibacterial activity of Physalis minima Linn extracts were also studied using disc diffusion method. The activities of methanol extracts were tested and had showed good inhibition zone against Staphylococcus aureus.

Green tea becomes one of the most popular beverages consumed worldwide, because of its many scientifically proven advantageous effects on human health it has gained attention in recent years . which is also rich in health-promoting flavonoids account 30% of the dry weight of a leaf, includes catechins and their derivatives. Several studies has proved that green tea catechins, such as epigallocatechin gallate, prevent growth of periodontal pathogens and decrease the destruction of periodontal tissue.

Oral cancer is the main leading cancer in India and 80% of Oral malignancy is analysed and diagnosed in the late stage. Oral Potentially Malignant Disorder (OPMDs) are the precursors of Oral malignancy. Delay in the diagnosis and screening is the main reason for the high death rate for oral cancer. Early Screening and treatment are an important role to prevent the progression of OPMDs into oral malignancy and also control the death rate. This Review article is to give the various clinical chairside screening methods using advanced techniques to detect the OPMDs.

The main aim of this review article is to provide information about Dentin Hypersensitivity(DH). Dentin Hypersensitivity ,a common condition of the teeth, characterized by short sharp pain arising from exposed dentinal tubules in response to stimuli. The article reviews its clinical features, pathogenesis, mechanism, diagnosis, prevention and management. The diagnosis should be accurate and all the differential diagnosis should be omitted. Desensitization remains the major choice for dentin hypersensitivity. The basic principle of treatment of dentin hypersensitivity is to block the patent tubules or block pulpal nerve response.

Bleeding gingiva can be a sign that the patient is at risk for gingival disease. It may be due to serious medical conditions such as leukaemia and bleeding and platelet disorders. The main cause of the gingival bleeding is the build-up of plaque at the gum line. This article explains deeply about the etiological agents, risk factors, microscopic features associated with gingival bleeding and care for oral health.

Hyposalivation is the reduction of salivary flow and Xerostomia is the sensation of having a dry mouth. Patient with this sensation of dry mouth will also have a noticeable and measurable decrease in the amount of saliva in their mouths, a condition referred to as hyposalivation. Saliva is a key element in oral homeostasis, oral function and maintenance of oral health. Dry mouth has multiple oral health consequences and affects quality of life. This article emphasizes on the oral complications and lesions that can be commonly encountered among patients with hyposalivation.

The presence of numerous keratin pearls on microscopic study is a feature commonly seen in well-differentiated squamous cell carcinoma. Pleomorphic adenoma (PA) can show the presence of squamous metaplasia with keratin pearls as a rare finding. This article present a short review on this rare variant of pleomorphic adenoma which exuberant squamous metaplasia and keratin cysts formations in salivary gland keratinizing pleomorphic adenoma .

Dental Stains are pigmented deposits on the tooth surface which are either extrinsic or intrinsic in nature. A dental stain compromises the aesthetics of an individual. Their prevalence may vary through geographic location, age, sex, habit and diet of an individual. Since there are a lot of variation between different types of stains there is a need to classify them for easy diagnosis and management. As dentists, we should be able to diagnose the type of stains and help those patients by providing them with choices to choose the most conservative treatment plan with an aesthetic outcome. This article aims to give an insight into the prevalence, aetiology and classifications of dental stains.

Mucormycosis is a rare angio invasive infection mainly recognized in immunocompromised patients which occurs due to the fungi mucorales. This rare fungal infection can be classified into rhino-orbitocerebral, cutaneous, disseminated, gastrointestinal, and pulmonary types. Inspiote of aggressive treatment once detected or diagnosed overall increased mortality rate is reported. This review aims in providing with brief details regarding the Etiopathogenesis of Mucormycosis, fatality of rhinocerebral Mucormycosis along with recent advances in diagnostic and treatment methods

Oil pulling is a traditional therapy rehearsed in old India. It is accepted to treat more than thirty systemic diseases when rehearsed routinely and as coordinated. Because of event of results to present day medications and oral hygiene products, individuals are progressively pulled in towards reciprocal and conventional practices. Oil pulling notwithstanding offering a few oral and medical advantages has likewise gainful consequences for by and large wellbeing. The current article endeavors to review and describe this antiquated practice.

Menopause is a physiological activity in women which brings changes at both systemic and oral level. At old age, oral hygiene and oral health becomes a major problem and the dentist are the ones who find those changes in the body throughout the menopause. The gums and teeth are more prone to changes in hormones that take place before menopause and slows down body’s capacity to fight back minor infections too. This article reviews about dry mouth during menopause which is of major concern which causes xerostomia.

Sjogren’s syndrome (SS) is a slowly progressive chronic autoimmune disease characterized bychronic inflammation of the exocrine glands. Xerostomia, Keratoconjuctivitis sicca and the B-lymphocytes hyperactivity are the characteristic features of the syndrome.Sjogren's syndrome (SS) also called as “Mikulicz disease” and “Sicca syndrome”. Lacrimal and salivary glands are most affected, which leading to mouth dryness and eye dryness.Sjogren syndrome can exist by itself known as primary Sjogren syndrome or associated with another disorders such as systemic sclerosis, rheumatoid arthritis, primary biliary cirrhosis or Hashimoto thyroiditis (associated secondary Sjogren syndrome).

Forensic odontology is a speciality in dentistry which occupies a primary niche within the total spectrum of methods applied to medico legal identifications. Forensic odontology deals with human identifications based on dental records, bite marks, lip prints, tooth prints and palatal rugae patterns. This article primarily aims at making general practitioners aware about the importance of keeping various types of dental records and its implication in forensic odontology.

Barodontalgia is the oral (dental or non dental) pain due to changes in the barometric pressure. With the increase in the number of pilots, SCUBA divers, air passengers , may encounter related oral conditions as they are more subjected to changes in pressure. This is not a pathological condition but a symptom. The common pathologies include faulty restorations, caries , periapical inflammation. This article reviews the etiology, pathogenesis, diagnosis and prevention pertaining to Barodontalgia.

Oral Cancer is a deadly infection, causing serious mortality and morbidity globally. Almost all oral cancerous lesions are derived from Oral potentially malignant disorder (OPMD). Among overall 60 to 70% of the Indian patients were introduced for therapy just in the advanced stage of oral malignant growth prompting a high death rate. The absence of public awareness about the screening and treatment during the premalignant stage along with the lack of knowledge for early detection by medical and health care providers are the main reason for this diagnostic delay and treatment initiation. This article aims to give different treatment options for Oral Potentially Malignant Disorder (OPMD) to prevent the progression of OPMD into malignancy.

Airway management is a significant worry in patients with maxillofacial injury, on the grounds that an undermined airway route may prompt demise. There are numerous alternatives accessible, every one has specific signs. As a rule, endotracheal intubation is normally not a feasible choice, but rather nasotracheal intubation and tracheotomies can be performed. These two techniques are known to have difficulties. Two options that can be picked are the submental and submandibular intubation procedures.

Temperomandibular joint pain and its disc disorder are the quite difficult in diagnosis and treatment planning where the pathological variation of the temporomandibular space infection varies from one region to the other. the adhesion of the temporomandibular joint space can be treated with arthrocentesis which was earlier done arthroscopy by ohinski and niten et al over 1991 in tmj.

Bifid condyle an exceptional and a rare disorder presents with the duplication of the condyle head. Incidence rate- 0.31% to 1.82%. Szentpetery et al, the incidence of bifid condyle to be 0.48% in 1,882 cadaveric skulls. In 1941, Hrdlica first diagnosed on a 21 cases of specimen Smithsonian Institution in Washington DC of which 18 were unilateral and 3 bilateral. In 1948, Schier reported the first live case of bifid condyle. According to Cowan and Ferguson 1997, at least 36 clinical cases of BMC

Background:
Genioplasty is a procedure provides proper chin configuration which is an important component of facial aesthetics. The jawline can improve the ordinary agreement and balance of the face, when it is in suitable size, shape and position. It can essentially degrade wonderful face and will pass on undesirable and unfortunate ascribes when it is wrong. The pervasiveness of obstructive sleep apnea turns out to be more evident now-a-days and its conclusion are more incessant, so for the recreation of the upper airway route, genioplasty has likewise advanced to a most normally performed method. This review article pointed toward talking about the clinical assessment and careful strategies utilized in genioplasty surgical procedure done for accomplishing appropriate jaw design.
Conclusion:
From the time of its presentation, genioplasty systems have gone through noteworthy changes and alterations. These progressions have improved the results and fundamentally diminished the confusions from the orthognathic techniques. Then again, since the presentation of the osteoplastic procedure, its utilization has been extended to address jawline disfigurements in each of the three dimensions. flexibility of the genioplasty methodology, notwithstanding the lower rate of related entanglements, settles on it the strategy of decision to address lower facial disfigurements, paying little heed to their inclination.

The objective of this study is to evaluate the implant survival and success in the younger population against the elderly population in South Indian population, a comparative study. It is a comparative study; following the placement of Single Posterior dental implants in patients with different age group.

Background: Temporomandibular joint arthrocentesis represents a form of minimally invasive surgical treatment in patients suffering from internal derangement of temporomandibular joint which is a simple, inexpensive and highly efficient procedure.
Arthrocentesis changes the synovial fluid viscosity contributing to the translation of the disc and mandibular head complex.Drug is instlledunder pressure directly on to the TMJ to breakdown early adhesion generating shear free jaw movements.thus mouth opening is improved, pain is decreased as proinflammatory mediators are washed out.
Material and methods: The present study was carried out in the department of oral and maxillofacial surgery at sree balaji dental college and hospital ethical committee clearence was obtained prior to study .the patients were informed about the surgical procedure the risk associated and informed consent was obtained from all the patients.
Conclusion: The lysis of adhesion of adhesion is achieved by intermittent distension of the joint space by momentary blocking of the outflow needle and injection under pressure during lavage using both SPA and DPA

Background:
There are various methods of tissue destruction have been employed in the field of oral and maxillofacial surgery like chemicals, irradiation by X-rays and high-frequency electric current and other methods. However any technique in question with the surgeon’s scalpel should be painless, produce minimal damage to the surrounding tissues, should be selective against, for example, malignant cells, it is very much applied locally, promote uneventful healing rapidly and provides good control. Cryosurgery is a therapeutic method of treatment in which inflammation and destruction tissue cells is created by high cold freezing. This review article aimed to throw insight into the efficacy of cryosurgery in the treatment of oral and maxillofacial lesions.
Conclusion:
With the recent development of better equipment and use of liquid nitrogen, this mode of therapy appears to have promising role in the management of locally aggressive and recurrent lesions in the maxillofacial region. Thus, its ease of application and the absence of postoperative infection, contraction, scarring with little or no recurrence makes cryosurgery a highly useful method in treating various conditions of oral cavity. Cryosurgery procedure can be done in out patient clinic, very much cost feasible and comparatively in treating various oral lesions. It is an less invasive form of therapy when compared to the conventional surgery. Cryoprobes can be used as an adjuvant material with other surgical methods in treating various types of oral lesions. In conclusion there would be a considerable increase in the use of cryotherapy in oral surgery, along with a much better understanding of the basic principles and techniques related to this form of treatment.

Background: Cyanoacrylate(CA) adhesives have a variety of application in medicine and dentistry as a tissue adhesive.CA saves time by more rapid closure and might serve as a suitable alternate to traditional suturing it however carries its own advantages and disadvantages. The aim of this paper is to evaluate the use of CA adhesives in various oral surgical procedures. Materials and methods: A literature search was carried out in PubMed central and Medline Database with keywords oral surgery, tissue glue, cyanoacrylate, tissue adhesive.

Background:
Distraction osteogenesis (DO) has become a well known useful procedure now-a-days in the field of oral and maxillofacial surgery, as we know initially this technique was used in the limbs, that is in the long bones but slowly thanks to its success in that area it potentiated the use of this procedure in the mandible, then gradually into the maxilla and now it has become a widely used procedure in the cranio- maxillofacial deformities. This review aims to provide an insight into the role of distraction osteogenesis in the cranio- maxillofacial deformities.
Conclusion:
The patients with cranio- maxillofacial deformities has more functional problems, poor aesthetics, muscular imbalance, improper oral hygiene, and sequelae of problems will follow it. So, distraction osteogenesis has become boon for those patients with such deformities. Distraction osteogenesis procedure has clinically showed that it is a versatile technique that it can performed with orthognathic surgery with proper planning and also supports the surgical treatment of tmj ankylosis by relaxing the airway obstruction caused by it. The worthiness of this procedure increases day by day in modern surgery and is definitely a key in oral and maxillofacial surgery.

Background: highly defected area or an infected area where required for the reconstruction of the structure .when the local flap or an regional flap are unsupported or insufficient for the reconstruct the area. free flap are used for the reconstruction . the donar and the recipient area are far away from the region of reconstruction . various type of reconstructive free flaps are available in the reconstruction of head and neck region with numerous advantages and disadvantages. The article is an literature review of free flap in head and neck region .
Material and methods: Over 12 articles where selected for review following comprehensive search of the literature from pubmed central.
Conclusion: free flap are used in the reconstruction of the head and neck region the success rate of the free flap are depends on the vitality and the vascularity of the donar and the recepient area will varies from region to region. Successive reconstruction of the recipient site by preventive necrosis therapy .

Oral metastatic lesions are rare. Different imaging modalities are used to identify the oral metastatic lesions. Knowledge and ease of identifying metastatic lesions in the oral and maxillofacial region is important. This systematic review is undertaken for that purpose.To explore the various imaging modalities and to identify the best imaging modality for diagnosing oral metastatic lesions.
A PUBMED search was done on august 2019 for articles published in the last five years, the search period being 2014 to 2019 using the title “ROLE OF IMAGING IN ORAL METASTATIC LESIONS”,”ROLE OF IMAGING IN ORAL METASTASIS” and “ROLE OF IMAGING IN ORAL METASTASES” with studies of following designs: clinical trials, clinical studies, case series/reports, prospective and retrospective studies. We retrieved 36 articles and found 11 articles that fulfilled our inclusion criteria. All included articles were those that were published within the last 5 years. Studies were classified based on the different imaging modalities used for identifying oral metastatic lesion and were tabulated.
This article will be a useful reference for further research for maxillofacial radiologists and orofacial oncologists regarding investigations for patients with metastatic lesions pertaining to the oral and maxillofacial region

LYMPHADENOPATHY (LAP) or ADENOPATHY is a any disease of the lymphnodes which is abnormal in size, number and consistency. Lymphadenopathy is a most common condition in any form of disease which is noticed by a physician .But it is not a peculiar symptom of any disease. An inflammatory type of lymphadenopathy is called as LYMPHADINITIS. In this review Article we can see the classification of lymphadenopathy pathogens, clinical approach and clinical evaluation of lymphadenopathy and differential diagnosis. Depending upon the size and extent of lymphadenopathy we can evaluate the condition of the patient and give appropriate treatment.

Extractions are the most common surgical procedures carried out and postextraction bleeding is most commonly seen complication. The aim of this review was to determine the effectiveness of topical hemocoagulase as a hemostatic agent and its role in reducing postextraction bleeding and its comparison to routine saline pressure pack after tooth extraction. Various differences was present between the hemostatic agent and saline pressure pack in relation to pain, swelling, wound healing, bleeding time, and other complications. Topical hemocoagulase is effective in reducing bleeding, pain, and swelling after extraction when compared to saline pressure packs. It also act as a promoter of wound healing.

Maxillary canine impactions are the second most common impactions following mandibular third molar impaction . There is always a confusion for the the clinician regarding the management of canine impactions, hence they need to be familiar with the differences in the surgical management of the labially and palatally impacted canines, the best method of attachment to the canine for orthodontic force application, the advantages of one-arch versus two-arch treatment, and the implications of canine extraction. The following review focusses on the various factors that influence all these decisions .

Introduction: This article intends to review the past and newer concepts in implantology, to gauge the long-term success of an implant.
Materials: The standards like presence of infection, discomfort, paraesthesia or anaesthesia, bone loss, gingival health, pocket depth, durability, effect on adjacent teeth, function, aesthetics, intrusion on the mandibular canal, patient's emotional and psychological attitude and satisfaction are considered in evaluation. Earlier concepts, given by Schnitman and Schulman(1979), Cranin et al(1982), McKinney et al. (1984) were evaluated along with newer concepts like the influence of width of attached gingiva, type of suture material used, associated medical conditions, smoking, width of the implant, genetic and immunological markers, exposure to radiation therapy and the type of flap used.
Results: Relating positive and negative factors of implant success gives the implant quotient. While earlier, the evaluation of implant success revolved round the stability, immobile, peri‑implant radiolucency, loss of marginal bone and absence of infection or discomfort to the patient, the recent studies show that attached gingiva width, co‑existing medical conditions, smoking, width of the implant, suture material used, all play a crucial role in implant success. The genetic and immunological factors like TNF‑α and IL‑1β are identified as diagnostic markers for implant success.

Osteomyelitis[1] of maxilla is a rare entity. It is more common in the mandible than maxilla. It is a rare entity in maxillofacial region and difficult to treat. Treatment of this condition involves sequestrectomy and debridement[2] of the necrosed bone and extraction of the involved teeth, most commonly bicuspids and molars. This article presents about a case of maxillary osteomyelitis and its treatment.

Platelet-rich plasma, or PRP, is now widey used in wound healing in the field of dentistry. Following any surgical procedure , blood clots initiate the healing and regeneration of hard and soft tissues. Several studies are being carried out to investigate the use of PRP in dentistry as a way to enhance the body’s natural wound-healing mechanisms.

Dental implants are commonly used in situations for replacement of natural teeth. Despite many advances, techniques, and implant-design, implant failure is a significantconcern for the patient and dentist. The dental implants are designed that best suits the various types of bone. Different etiology for the implant failure and their contributing factors has been discussed in this review article. The purpose of this concise review is to discuss the etiology of implant failure by highlighting the various classification put forth by different authors

Since the onset of LASER in dentistry , it have been first priority in treating oral and maxillofacial surgery.Because of its efficacy and portability , LASERS are more common among dental practitioners.Over the decades, lasers are used in all field of treatment in dentistry.The purpose of this article is to improve technology and further study of lasers and its wavelength inorder to reduce complications.This article provides the introspection towards the wide application of LASERS in oral and maxillofacial surgery.

Nonsurgical therapy aims to eliminate bacteria within the microbial biofilm and calcified biofilm microorganisms from the tooth surface and adjacent soft tissues. Complete elimination of such pathogenic microorganisms is probably over-ambitious. However, absence of inflammation in the periodontium results in beneficial clinical changes.In addition, nonsurgical therapy aims to form an environment during which the host can more effectively prevent pathogenic microbial recolonization using personal oral hygiene methods..The various methods utilized in nonsurgical therapy, like hand instrumentation, ultrasonic and sonic scalers, and ablative laser therapy

Plaque- induced gingivitis is a highly prevalent periodontal disease. It is caused by formation of microbial biofilm on the tooth surfaces, poor oral hygiene. Treatment of plaque induced gingivitis concentrates more on plaque control by various methods. The purpose of the study was to conduct a systematic review of efficacy of daily rinsing with piper betel extract mouthwashes in terms of Plaque Index (PI), and/ or Gingival Index (GI) as compared to other mouthwashes in plaque-induced gingivitis.an electronic search was carried out using the key words ‘herbal mouthwash’ ‘ piper betel’ ‘anti-gingivitis effect PubMed/Medline, ISI Web of Science and Google Scholar databases for relevant articles published from 2014-2019. The addressed focus question was: Is herbal mouthwash effective as an anti-plaque or anti gingivitis agent than other chemical mouthwashes? Following the removal of the duplicate results, the primary search resulted in 20 articles and twelve articles were excluded based on title and abstract. Hence, 9 articles were read completely for eligibility. After exclusion of 2 irrelevant studies, seven articles were included. Mostly RCT’s, all are human studies. Conclusion: Herbal mouthwashes like Piper Betel mouthwash can be used as an adjunct to various oral hygiene practices like tooth brushing, flossing. Its proven that they have effective anti-inflammatory, anti-plaque properties and hence can be used in supportive periodontal therapy. It does not contain alcohol, artificial preservatives, flavours or colours. Hence Piper Betel based mouthwashes can be considered an alternative to chemical mouthwashes in sustaining oral hygiene, especially because of the added advantages provided by herbal preparations.

Gingival overgrowth is characterized by the accumulation of extracellular matrix in gingival connective tissues, particularly collagenous components with various degrees of inflammation.
Gingival overgrowth can result due to inflammation, infections, neoplasms, endocrinal, drug induced.
Drug-induced gingival overgrowth is a side effect of drugs used in treatment of systemic diseases.
The common drugs which cause a gingival overgrowth are,
- Anticonvulsants ( phenytoin ),
- Immunosuppressive agents (cyclosporine A),
- Calcium channel blockers in CVS diseases.

The ultimate goal in successful management of mobile teeth is to restore function and comfort by establishing a stable occlusion that promotes tooth retention and the maintenance of periodontal health. The clinical management of mobile teeth can be a perplexing problem, especially if the underlying causes for mobility have not been properly diagnosed. In some cases, mobile teeth are retained because patients decline multidisciplinary treatment that might otherwise also include strategic extractions. Some mobile teeth can be treated through occlusal equilibration alone whereas mobile teeth with a compromised periodontium can be stabilized with the aid of provisional and/or definitive splinting. Tooth splinting have been accomplished since ancient civilizations to decrease tooth mobility, to replace missing teeth & to improve form, function, and esthetics. Still splinting remains one of the poorly understood & controversial areas of dental therapy. This article discusses splinting…its, rationale, basic principles, indications, contraindications, limitations and classifications.

This study was to examine the symptoms and risk factors associated with self-reported xerostomia. Data were collected from 601 self-administered questionnaires among dental clinic attendees. Logistic regression models to estimate odds ratios and 95% confidence intervals were used to investigate the association for exposures of interest, such as socio-demographic characteristics, self-reported symptoms, oral hygiene habits and xerostomia. Participants reported having dry mouth in 19.6% of cases. Xerostomia was associated with a significant increase in the odds of having dry lips, throat, eye, skin and nose. Patients with self-reported xerostomia were three times more likely to drink water to swallow food than were patients without xerstomia.

Dental implant placement using flapless surgery is minimally invasive technique which improves blood supply compared with flapped surgery. Objectives: The aim of this systematic review was to evaluate the clinical parameters following implant surgery in healed sites, using 2 procedures: flapped vs flapless surgery. A detailed electronic search was carried out in the PubMed/Medline, Scholar Library databases. The focused question was, what is the efficacy of flapless surgery compared to the flapped approach?” .All the studies included with a prospective controlled design were considered separately, depending on whether they are being conducted on animals or humans. The following data were recorded in all studies: number of implants, failures, location (maxilla, mandible), type of rehabilitation (partial or single), follow up and flap design. The variables selected for comparison in animal studies were : flap design, gingival index, mucosal height, recession and probing pocket depth. In humans studies the variables were as follows: flap design, plaque index, gingival index, recession, probing pocket depth, papilla index and keratinized gingiva. Results: Ten studies were included, of which 2 are excluded because of irrelevance, out of which 6 where human studies and 2 were animal studies. Results obtained showed that human studies proved that the flapless implant approach proved to be efficient over flapped approach whereas the animal studies showed no significant differences between the two.

Nonsurgical therapy for the control of periodontitis consists of sub-gingival debridement, with oral hygiene instructions. Sub-gingival debridement without oral hygiene measures results in a limited healing response. Instruction on oral hygiene in the absence of sub-gingival debridement results in a suboptimal response clinically. The basic approach to periodontal infection has always been the removal of supra & sub-gingival bacterial deposits by scaling & root planning. Certain other aids such as the irrigants which are used by home or professional methods are also there other than mouth washes and systemic antibiotics. Newer advancements such as the local drug delivery the vector system and the probiotics also help in improving the maintenance of the oral hygiene status.

Furcation involvement is defined as bone resorption and attachment loss in the bifurcation and trifurcation of multirooted teeth that results from plaque associated periodontal disease. Prevention of periodontal disease progression along with lost periodontal tissues regeneration forms the main goal of periodontal treatment. Platelet-rich fibrin (PRF), is a second-generation platelet concentrate incorporates platelets and growth factors within fibrin membranes. In recent times platelet rich fibrin plays a important role periodontal regeneration. The aim of this review is to systematically evaluate the clinical efficacy of platelet rich fibrin as an adjunct in the treatment of grade 2 furcation. A systematic search was carried out in electronic database PubMed and google scholar using the key words furcation, bone defect, plasma rich fibrin. Relevant outcomes and data were extracted from the included studies. Following the removal of the duplicate results, the primary search resulted in 33 articles and 21 articles were excluded based on title and abstract. Hence, 12 articles were read completely for eligibility. After exclusion of 4 irrelevant studies, eight articles were included. All were RCT’s, two human and six animal studies.

Every human body has many microbial communities, there are certain group of microbial communities called as the oral microbial community, these microbiomesare healthy unless and until they are triggered by certain environmental factors that enable them to produce disease. The microbes are being identified and sequenced by certain methods such as DNA hybridization and the PCR techniques and these microbes are found to be specific at specific siteswhich are given by site specialist hypothesis and it is also found that specific microbes are for specific persons hence it can help with the concept of the personalised medicine. It is found in recent years that tolerance to these microbes can also be developed to the foetus prenatally itself with the help of the mother’s microbiome

The aim of this review article is to outline the use of surgical microscope and microsurgical loops in enhancing and removal of calculus under magnification. The use of high level magnification combined with head mounted coaxial lighting may improve the ability of dentist to perform prophylaxis. The detection and removal of calculus located subgingivaly can be visualised by magnified view of supragingival contours. Use of magnification, facilitates improved visual acuity, rapid wound healing and increased acceptance by the patient

COVID-19 (corona virus disease 2019) originated from Wuhan, china at the end of 2019 affected not only china but also spread all over the world and became a pandemic which was announced by WHO at march 2020. To prevent the spread of this corona virus disease many countries around the world announced Lockdown for several months. The people were asked to quarantine in their homes. All the Educational institutions like schools, colleges and universities are closed. It made a huge impact on health professionals and dental education. To avoid close contact between students, dental schools, colleges and laboratories were closed. so various virtual modes were undertaken to deliver Dental education in three different categories - lectures & problem based learning, Iaboratory training and clinical training. Although virtual modes of education had advantages, it has many disadvantages. The disease also has impact on dental research. In conclusion, though the pandemic caused more challenges to dental students and dental education, it paved a new way for Revolutionary modifications in dental education.

Implant Surgeon Gary Greenstein,* † John Cavallaro,* ‡ and Dennis Tarnow* § A proficient knowledge of oral anatomy is needed to provide effective implant dentistry. This article addresses basic ana- tomic structures relevant to the dental implantologist. Pertinent muscles, blood supply, foramen, and nerve innervations that may be encountered during implant procedures are reviewed. Caution must be exercised when performing surgery in certain regions of the mouth. Furthermore, numerous suggestions are provided regarding the practical application of anatomy to facilitate successful implant therapy Review Practical Application of Anatomy for the Dental Implant Surgeon Gary Greenstein,* † John Cavallaro,* ‡ and Dennis Tarnow* § A proficient knowledge of oral anatomy is needed to provide effective implant dentistry. This article addresses basic ana- tomic structures relevant to the dental implantologist. Pertinent muscles, blood supply, foramen, and nerve innervations that may be encountered during implant procedures are reviewed. Caution must be exercised when performing surgery in certain regions of the mouth. Furthermore, numerous suggestions are provided regarding the practical application of anatomy to facilitate successful implant therapy Review 
Practical Application of Anatomy for the Dental Implant Surgeon Gary Greenstein,* † John Cavallaro,* ‡ and Dennis Tarnow* § A proficient knowledge of oral anatomy is needed to provide effective implant dentistry. This article addresses basic ana- tomic structures relevant to the dental implantologist. Pertinent muscles, blood supply, foramen, and nerve innervations that may be encountered during implant procedures are reviewed. Caution must be exercised when performing surgery in certain regions of the mouth. Furthermore, numerous suggestions are provided regarding the practical application of anatomy to facilitate successful implant therapy
A proficient knowledge of oral anatomy is needed to provide effective implant dentistry. This article addresses basic anatomic structures relevant to the dental implantologist. Pertinent muscles, blood supply, foramen, and nerve innervations that may be encountered during implant procedures are reviewed. Caution must be exercised when performing surgery in certain regions of the mouth. Furthermore, numerous suggestions are provided regarding the practical application of anatomy to facilitate successful implant therapy.

Minimally invasive procedures are the new paradigm in health care. Everything from heart bypasses to gall bladder, surgeries are being performed with these dynamic new techniques. Dentistry is joining this exciting revolution as well. Minimally invasive dentistry achieves the treatment objective using the least invasive surgical approach, with the removal of the minimal amount of healthy tissues. This paper reviews in brief, the concept of minimal intervention in dentistry.

A Veneer is a layer of tooth colored material that is applied to a tooth to restore localized or generalized defects and intrinsic discolorations. Veneers are made from materials like chairside composite, processed composite, porcelain, ceramic, preformed acrylic laminates and glass ceramic veneers. The evolution of materials, ceramics and adhesive system helps in improving the aesthetics and self-esteem of the patients. The current article is a review that illustrates the recent advancements in material aspect and clinical techniques of dental veneers.

Prior to root canal treatment at least one undistorted radiograph is required to assess canal morphology. A correct working length with the help of Radiograph or Electronic Apex Locator is one of the critical factors for the success of Endodontic Treatment. Short measurements may leave parts of the Root Canal un-instrumented. On the other hand, over instrumentation with enlargement of the apical constriction may result in damage to peri radicular tissues. Therefore correct working length has a role in treatment success. Compared to Radiograph, Electronic Apex Locators reduces the number of radiographs and assists where radiograph method is difficult to access. This review of literature focusses on the insight into electronic apex locator. Search engines used are, PubMed and Google Scholar.

External cervical resorption (ECR) is a type of external root resorption. ECR is relatively uncommon and the etiology is not very clear. Often misdiagnosed leading to improper management or tooth loss.Clinicallyit’s often asymptomatic unless pulpal or periodontal involvement begins. ECR is mostly noted in routine radiograph. Accurate assessment of the true nature and accessibility of ECR is important for its effective management

Single rooted tooth are regarded to be the easiest tooth to perform root canal treatment. Single rooted tooth showing more than single canal cases has been documented in the literature. The inability to detect the presence of second canal is the main cause for unfavourable outcome during endodontic treatment. Complete cleaning and shaping with copious irrigation is the key to successful endodontic treatment. Cleaning and shaping procedures requires careful understanding of the internal anatomy and morphology of the root canal system. Thepresent case report presents a rare entity of two separate canals in mandibular anterior teeth, detected while performing routine endodontic treatment.

Dental adhesives are used to bond composite resins to tooth structure. The earliest bonding systems required an acid-etch technique and were only compatible with enamel. The challenge has always been to predictably bond to enamel and dentin simultaneously. The material should have such a property that it should have better retention to the dentin and it should be able to withstand forces of occlusion and mastication. The ideal requirements of an effective dentin adhesive system include the ability to thoroughly infiltrate the collagen pathways and partially demineralized zone, to encapsulate the collagen and hydroxyapatite crystallites, to produce a well polymerized durable hybrid layer with high bond strengths. As a hybrid layer is created by a mixture of the dentin organic matrix, residual hydroxyapatite crystallites, resin monomers and solvents, aging may affect each of the individual components differently or may result in synergistic combinations of degradation phenomena within the hybrid layer.

The endodontic success relies on chemo mechanical preparation, removal of microbial toxins, irrigation and complete obturation of the root canals. The key part of the treatment is hand and rotary instrumentation to eliminate microorganisms from the primary rootcanal by the action of direct mechanical cleaning.The maingoal of instrumentation is to facilitate disinfection,effective irrigation and filling.The intricacy of rootcanal morphology provides curved apical third,apical deltas, narrow isthmi, oval and ribbon shaped canals cannot be mechanically cleaned.Bacteria can flourish in these untouched areas and it turned out to be a challenging objective to endodontic and also a real cause for pulpal and periapical diseases.Complete disinfection of canal is difficult with single irrigating solution use of two or several irrigating solutions obtain the goals of effective and safe irrigation. Irrigation has been performed with plastic syringe it allows good control of needle depth. The purpose of this article is illuminate the methods of effective and safe irrigation on the latest advancements

Mineral trioxide aggregate(MTA) seems to be an all-rounder material which is used invarious field of dentistry such as endodontic treatment.Here is an overview of the composition, properties, biocompatibility, setting, clinical uses, indication, contraindicationof MTA, conclusion

The goal of endodontics is the preservation of natural dentition. Conventional endodontic treatment are performed to obturate the disinfected root canal system with filling materials such as guttapercha. Although orthograde treatment has a very high success rates, these teeth are devitalized and therefore susceptible to reinfections and fractures.The American Dental Association (ADA) formed several clinical codes for regenerative endodontic procedures in necrotic immature permanent teeth in children and adolescents. It provides a new perception and perspective in many dental specialties, including endodontics. Recenlty REP also shows promising results in mature teeth. The aim of this review was to explore the potential of REP application in adults, who consists of the great majority of endodontic patients.

To assess the relationship between the maxillary sinus floor (MSF) and the maxillary posterior roots using Multi-slice computed tomography (MSCT) in Indian population. Materials and Methods: MSCT images of about 604 maxillary sinuses from 302 patients were studied. The relationship of 2416 teeth and 5926 root tips consisting of first premolar, second premolar, first and second molar to the maxillary sinus were examined. Image analysis was done separately by an endodontist, a postgraduate student and a radiologist trained in MSCT. The observers has to assess the vertical relationship between the MSF and the roots of molar and premolar teeth which were noted as “g” for gap between root tip and MSF; “t” for root tip touching the MSF; “p” for root projecting into the sinus and the length of projection into the sinus was measured in millimeters. Data were recorded and statistical analysis was done.

Chronic periodontitis (CP), the most common periodontal disease, is an inflammatory disease leading to the destruction of connective tissue and loss of the adjacent supporting bone and is multifactorial in etiology. Periodontal therapy including either surgical and/or non-surgical methods usually results in improvements in periodontal health. In some cases, scaling and root planing (SRP) is insufficient to solve periodontal infection. SRP combined with local antibiotics has been shown to yield better results than SRP only. Recently, minocycline, a broad spectrum antibiotic is found to be effective against periodontal pathogenic micro-organisms.
The aim of this systematic review is to evaluate the clinical efficacy of locally delivered minocycline in the treatment of periodontitis.an electronic search was carried out using the keywords, “minocycline”. “periodontal” and “periodontitis” via the PubMed/Medline, ISI Web of Science and Google Scholar databases for relevant articles published from 1949 to February 2019. The addressed focused question was: To review current literature, to analyse the efficacy of minocycline as a local adjunct to SRP in the treatment of periodontitis. Following the removal of duplicate results, the primary search resulted in articles and articles were excluded based on title and abstract. Hence, articles were read completely for eligibility. After exclusion of irrelevant studies,6 articles were included. All of them were RCT’s, all of them were human studies, were clinical and were microbial analysis.

Secure and stable cryptographic cash key affiliation is huge right by and by cash considering how the keys are the most ideal approach to manage find a better than average pace. Despite the way where that Exodus wallet plans have been proposed, some application goals and common security dangers notwithstanding everything exist. At this moment, propose a novel cryptographic cash wallet the administrators plot subject to Decentralized Multi-Constrained Derangement (DMCD) Hybird blockchains to store the keys securely and dependably in a decentralized framework. Filling in as the data stream framework, DMCD has high data dissipating and a staggering comprehension between the pace of additional room use and commitment, which can guarantee the security and nature of the key saving and recovery. In our approach, to adjust to the issue that center centers are as routinely as conceivable on the web and isolated in the decentralized structure, we use a Shamir-Kademlia-Neighbor (SKN) riches procedure to ensure the high openness of set aside key. Then, for achieving puzzling correspondence during DMCD data dispersal, in setting on the Kademlia show up, we change the Client/Server (C/S) framework for Hordes show to a decentralized variation. All the proposed advances can ensure that our arrangement constrains sublimely in a decentralized mode. The evaluations and assessments show that our game-plan is beneficial, stable, and secure in the decentralized framework. Our proposed is Exodus it's not just cryptographic cash is a phase for Decentralized Multi-Constrained Derangement (DMCD) Hybird blockchains(HB). We give modernized trust signature figuring to checked trade. We show that the trade designing time won't be basically influenced considering the structure nonattendance of goliath worth through wide duplicates on a private Exodus sort out.

The Indian culture and tradition, Indian value patterns has gone through many stages as the younger generation people wanted to go behind western culture. The joint family is breaking down under various economic, social and industrial powers. Even the urban Indian society wanted to retain its togetherness of family ties. The tradition and the environment become incompatible. The socio-economic cultural contrast is sustained between the Indian and western culture. The social and the cultural freedom should not go beyond the traditional values followed in the family.

Transaction fraud is predominant nowadays as many people prefer shopping through online. This made the research on detecting fraud to become an important part of research at present times. Based on records of transaction of several users, Bp (Behavioral Profile) is extracted and then verification takes place in order to find the frauds occurring. Usage of Markov models does not give relevant results, thus making unsuitable to use in such scenarios. Attributes from several transaction records are classified in the proposed system to represent a graph like structure. The probability of path from one attribute to another is calculated along with computation of diversity of several different users behaviors in transaction. For every user a Bp is constructed and is verified whether the transaction is allowed incoming or not to detect the fraud. The experimental results show the efficacy of the system.

Data adequacy on Twitter has been a point of energy among experts in the fields of both PC and humanistic frameworks, for the most part as a result of the nonstop headway of this stage as a mechanical get together for data spread. Twitter has made it progressively conceivable to offer the close interminable exchange of data in a utilitarian way. It is correct currently being utilized as a wellspring of news among a wide bundle of clients around the world. The gloriousness of this stage is that it passes on a profitable substance in a custom-fitted way that makes it achievable for clients to get the news with respect to their subjects of intrigue. In like manner, the progress of methods that can check data picked up from Twitter has become a problematic and fundamental errand. Right now, propose another worthiness evaluation framework for surveying data authenticity on Twitter to avoid the expansion of phony or vindictive data. The proposed structure incorporates four encouraged pieces: a notoriety based segment, a dependability classifier motor, a client experience parcel, and a segment arranging calculation. The pieces coordinate in an algorithmic structure to examine and evaluate the validity of Twitter tweets and clients. We gave the presentation of our framework a shot two undeniable datasets from 489,330 novels Twitter accounts. We applied 10-overlay cross four AI figurings. The outcomes uncover that a gigantic congruity among review and precision was developed for the endeavored dataset.

Diaspora is a term that encompasses cultural and emotional conflicts. Nationality and nativity contradict each other in the diasporic context. Nativity is an innate emotional bonding that creates a sense of belongingness, while nationality limits itself to the physical presence. Diasporic writings record the immigrants ‘strivings to feel the warmth of native land in a foreign nation across the boundaries. Adaptation in a foreign country is highly influenced by the socio-cultural factors and in other words, these are the crucial factors in determining the immigrant life of an individual. Diasporic literature focuses on reflecting the realistic experiences of the people away from their homeland and also in breaking the myths surrounding their lives. Though India within itself has multicultural shades, Indian immigrants in other countries are still encountering the disillusionment and struggle to cope up with the different environment. The British colonialism in India plays a pivotal role in the migration of Indians to various countries, especially, England and America. Most of the Indian diasporic writings deal with the immigrants’ social and psychological confrontations in these two countries and the effects are greater upon the women due to their social status. Jhumpa Lahiri had written vintage diasporic novels and stories in which she takes the readers across the nations to visualize the life of a migrant from a developing nation to a developed nation. As a woman writer, her representations of women characters are highly realistic and deeply moving. Her famous short story collection, Interpreter of Maladies includes nine short stories and each story projects the different dimensions of diaspora through the various characters sketched in the story. The paper attempts to decode the myriad diasporic elements in Jhumpa Lahiri’s short stories and also to study the impact of diasporic experiences over the ages.

Employers and societies more and more ask for capable and ready to work graduates, possessed with some amount of competences when getting into the workforce. But they want for very skilled employee has been mounting, the difference between capabilities of graduates and educations searched by the employers remain to be a thoughtful concern among many nations. The factors that affect the growth and sustainability of the graduates are solely due to lack of non-technical skills such as team spirit, communicative skills, decision making and solving the problems that exist in course of time and creative skills. The important subject addressed by the current study is to identify the factors that influence the science and technology (S&T) graduates’ in respect to fitness for purpose. The findings showed that the S&T graduates voiced their opinions on the importance of non-technical skills which are essential for their survival and development in their respective professions. The vision-2020 has located science and technology as significant as the educational policies are often observed as effective forces behind economic growth in industrialized countries.

In this paper we have applied various classification algorithm to demonstrate better classifier to produce a hybrid selection of classifier. It is enlarged with weighted balloting on the idea of Out_Of_Bag blunders charge of man or woman decision bushes. As pre work, we first done evaluation of Random Forest the usage of five one-of-a-kind break up procedures; a unmarried split quantity is used at a time for whole forest. In this paper, we to start with proposed an superior random Forest that utilizes polluting affect optimization strategies just like the bushes in random forests. If there have to be an occurrence of accuracy development, inquire approximately is finished using exceptional belongings assessment procedures and consolidate capacities. A pass breed selection tree model alongside weighted balloting is proposed which recovers the accuracy. Development in getting to know time principally issues on diminishing range of base choice bushes in Random Forest with the aim that learning and for this reason, class is quicker. The methodologies proposed in the bearing of this direction are separate parcels of schooling datasets to get acquainted with the bottom choice bushes, and ranking of training bootstrap samples primarily based on first rate range. Both these methodologies are prompting efficient gaining knowledge of Random Forest classifier.

Today internet is playing a vital role in the modern world. From young aged children to old aged people are utilizing the technology. By the use of this technology to determine the mental taught of the student towards the learning environment the sentimental analysis method is performed. For this they created a separate portal for the student which has unique ID and password for individual one. Inside the web portal it consists of various sets of question and it records the performance of the student towards it. The feedback can be subdivided into three categories mainly positive, negative, and neutral. By using the feedback they can predict the sentiments of the student. By using the machine learning algorithm they can predict the sentiment of the students in the learning aspects. Student sentiment has been get distinguished by the use of the polarity. This is can uses the random forest algorithm. The random forest algorithm can provides the accuracy of about 92% with effective outcome.

Thousands of higher authoritydemonstrated that vehicle crashesand accidentsare caused by drivers unconsciousness. To guarantee thesecurity of people on the road network as far as feasible, it's vital to have the ability to predict the drivers'who aredriving safety risks safely in real time. The results of withstatistics published by the World health organisation. asshow that automobile crashes cause over 12 lakhsdeaths and more than 5croreinjurieshappenevery 365 daysand according to this data analysis from , it is found that young people between the ages of 14-28have the peakrangeof these crash events happeningwithhelp of database by using Hadoop tool we are able to test no restriction of data and simply add variety of machines into this bunch and also we receive results with less time, even eighth demanding put and miniatous price is less and we are using combines, partitions and bucketing methods in Hadoop.Hadoop is Opensource framework that includes modulated by the apache software base and It is used for storing and processing substantial data sets Hardware.We are employing spark we Can get consequence hundred times faste

The hexahydroacridine derivatives was synthesised and characterised by various techniques. Synthezied compounds were screened for anti- oxidant, anti inflammation, and anti diabetic activity. The compounds were screened for their Antioxidant activity was evaluated by DPPH radical scavenging method and compared with standard ascorbic acid. Anti inflammation activity were examined by albumin denaturation and compared with standard asprine. Antidiabetic activity against α-amylase enzyme and compared with standard drug acarbose

Now a day in this world most of them are affected by various types of diseases. So the use of medicine is increasing day by days. Every disease has some medicine to treat it. Medicine are of various types they are in the form of liquid, tablet, capsules, drops, injection etc. but in some situation everyone don’t have sufficient time to go to the medical shop for buying their medicines. But medicines are so important for the treatment of their diseases. In chronic type of health issues are based on the medicines availability. Sometimes absences of the medicines change the life of affected person. To avoid such kind of situation this proposed work provides the detail of all the medicine in the pharmacy are stored in with the help of the concepts of cloud computing is the on demand availability of the computer systems resources, mainly data storage and computing power without direct active management by the user.

The Internet of Things (IoT) is a powerful technology that can enable users’ smart devices and sensors to link each other and access the internet for daily usage. It is a platform that can be used by end users to access many smart application fields, such as smart city, smart home, and smart healthcare. In recent years, the healthcare monitoring systems are becoming the major development field that use the IoT as advanced technology enabler. This review is discussing more about the design, functions, and the main uses of the IoT-based healthcare monitoring applications and systems for remote patient environments. Therefore, a deep review has been made to identify the usage, efficiency, and acceptability for the current applications and systems to become more efficient to patients. Different healthcare monitoring systems have employed the IoT to integrate the different wireless interfaces with the cloud-based healthcare services. These services are including the sensing, gathering, processing, storing, and learning more among the patients’ data. The various IoT healthcare applications will help to develop useful and effective solutions by using these systems in practice. From this review it can be proof that the IoT-based healthcare monitoring applications are growing faster to build more healthcare solutions that useful for different healthcare conditions and environments.        

The coronavirus (COVID-19) pandemic is a great concern in the global health sector. This isdueto the large number of people infected within a wide area. The possibility of transmission from one person to anotherraises the need for isolation or restrictions in terms of physical and social interactions within the community. This study aims to determine the extent of community compliance in conducting Physical Distancing.
The research design was observational analytic, using cross sectional method,and was performed with 753 respondents. In addition, data was collected using internet-based questionnaire in the first Government Emergency Response period from March 23 to April 11, 2020. The information obtained includes demographics, physical social compliance variables and risk level. Therefore, qualitativeanalysis was performed to evaluate the frequency distribution, while the relationship between risk categories with Covid 19 cases was determined using chi square.
The results showed the majority of respondents performedoutdoor activities (60.4%), althoughwith good health protocol awareness. Also, mostparticipants wear masks (75.6%), conductgoodhand washing habit (86.6%), always use hand sanitizers (76.5) and maintain a distance from others (87%). Furthermore, the risk categories of respondents were low (95.2%),hence a relationship is established between Covid 19 cases and risk categories.This is reflectedin physical and social distancing compliance (p <0.00001),classified in the moderate category,with an odd ratio value of 9.42 (CI: 4.45-19.97).
In conclusion, moderate physical and social distancing compliance poses a greater risk for covid19 cases, thus the need to increase discipline with Large Scale Social Restrictions (PSBB) implementation.

Background: since its founded, sars-cov-2 (covid-19) has spread throughout the world including indonesia and west papua. When who calls for an international health emergency, efforts to prevent the spread of covid-19 must be based on personal activities supported by internal and external factors.
Objective: to determine the influence of knowledge, attitudes, family support and lifestyle factors related to mental health on covid-19 prevention behavior
Methods: this study was cross-sectional in design. The subjects consisted of a consecutive sampling of 159 respondents from all people in west papua who got research information, were able to use smartphones and the internet. The questionnaire was created using google form and distributed using the social media application whatsapp, instagram and facebook during april - may 2020. Logistic regression were used for data analysis.
Results: simultaneous family support, life style related mental health, level of knowledge, and attitudes did not affect the prevent covid-19 practice (f count 2.307). Sequentially, only attitudes (p-value = 0.038) which contributed to prevent covid-19 practice.
Conclusion: we suggest that if you want to reduce the incidence of covid-19 quickly, you need confirmation. Everyone in indonesia must become a social control to build positive narratives and change behavior because the behavior of new adaptation health protocols such as wearing masks, washing hands and maintaining distance, diligently exercising and consuming vitamins are healthy living behaviors.

Background
Tuberculosis (TB) is a problem in developing countries, because the rate of disease incidence is still high and included in the big 10 leading cause of death in the world. As TB prevalence cases increase, community participation in finding new TB cases is very important. The method that used by various countries is by community-based case finding or Active Case Finding in the community (Active Case Finding).
Purpose
Evaluating the program implementation in the discovery of new TB cases by TB careworker at the health center in an effort to control TB in DIY (Daerah Istimewa Yogyakarta, DIY).
Method
This type of research is a quantitative survey. The subjects are TB worker in Puskesmas Yogyakarta, as much 120 people. The instrument used was a questionnaire containing ways of case finding, knowledge, behavior, case finding constraints, types of activities, and main tasks. The analysis uses frequency distribution and is presented in tabular form.
Result
TB worker in Puskesmas DIY have taken several ways in carrying out new TB case finding; such as Active Case Finding, Pasive Case Finding, knock on the door, counseling, screening and screening. There are some obstacles in the implementation of the discovery of new TB cases; such as limited time and lack of personnel, lack of budget, multiple task burdens, and some areas that do not yet have cadres. The majority of TB careworker are nurses (90%). The aim of new TB cases found in DIY Province was only 48.3% from the target.

Balanced scorecard transforms mission and objective of companies in to inclusive measures for assessing performance which gives structure for effective management and measurement system. The results reveal that the employees are agreed with balanced scorecard is a good method for assessing performance, balanced scorecard is an effective planning tool, balanced scorecard helps in taking appropriate decision, balanced scorecard is useful to enhance competencies of employees, balanced scorecard assists employee to set their job priorities, balanced scorecard makes employees to realize their responsibilities and balanced scorecard give accurate feed back on performance of employees. There exits significant difference in consciousness of employees on balanced scorecard in IT companies and their features. Consciousness of employees on balanced scorecard is significantly, positively and moderately related with their performance in IT companies. Therefore, balanced scorecard should be highly flexible and it must be very easily understandable by employees. Besides, balanced scorecard should not give any threatening to employees.

With the rapid growth of COVID-19 pandemic infectious disease caused by the Corona Virus. It was first identified in Wuhan in December 2019. It expanded its circle all over the world and finally spreading its route to India. The whole world is fighting against the spread of this deadly disease, cases in India also gradually increasing day by day since May after lockdown. This article proposes how to contribute to utilizing the machine learning and deep learning models with the aim for understanding its everyday exponential behaviour along with the prediction of future reachability of the COVID-2019 across the nations by utilizing the real-time information from the Johns Hopkins. This paper studies the COVID-19 dataset and explore the data by data visualization with different libraries that are available in Python. The paper also discusses the current situation in India while tackling the Covid-19 pandemic and the ongoing development in AI and ML has significantly improved treatment, medication, screening tests, prediction, forecasting, contact tracing, and drug/vaccine development process for the Covid19 pandemic and reduce the human intervention in medical practice. However, most of the models are not deployed enough to show their real-world operation, but they are still up to the mark. Within this paper, we present Exploratory Data Analysis, Data Preprocessing, Data Cleaning and Manipulations, Machine Learning Algorithms, Pandemic Analyzing Engine GUI, and Deep Learning. We have performed linear regression, Decision Tree, SVM, Random Forest and for forecasting, we performed FBPrompet, ARIMA model to predict the next 15 day’s Pandemic situation.

Modern history holds a large number of intellectually productive writers to its list. With versatile noetic writings that howler the composite and distinguished themes like Elements of psychological depression, feminism and self realization, Paulo Coelho, irrefutably transcends the list. With his engaging authorship, the author Paulo Coelho helps the readers to light upon the position of feminism, to determine and reflect on one’s freedom and the urge to act upon depression in the modern-day society. This article discusses the select themes like self-realization, psychological depression and feminism in the novel.

and dives significant into the mind of the youngster Aza Holmes. Various things happen in Aza's life and the guideline point of convergence of the book is on her internal fight. We consume most of this story inside Aza's mind. Aza has a nearest buddy called Daisy. The story opens in the optional school cafeteria when Aza is experiencing a "Thought Spiral" as she calls it. Life is going on in the cafeteria as her buddy endeavours to partake in conversation; anyway Aza is trapped in her special contemplations. Aza is desolately lost supposedly and Daisy shares a sharp brain and a reverence for Applebee's. Daisy is overflowing with enthusiasm always and relationship, while Aza isn't. Aza and Daisy at the same time enhance and upset each other. The article below gives some idea about the emotional instability of a woman. All the difficulties and hardships that she has suffered in her life is portrayed and it is further analyzed on the basis of how the victim look for self identity. Society has not always stood for mentally disturbed people. Even though there are many associations and organizations for helping them, these people are still neglected by everyone. It is so rare that one gives a helping hand for people who are mentally not stable. Mental illness is common and widespread. It is not something that comes to only one person. Through this article, the emotional instability of a character named Aza is put forth and how she manages to live her life with all these things happening behind her mind is shown.

The term Religion and Spirituality are to be sure proportional of neither one another, however neither they are unfavourably inverse nor the equivalent. Religion and Spirituality are two untethered facts of uncanny reality. Religion is set of creeds, confidence, and ceremonies laid or established on supernaturally mediating belief systems (at any rate that is what is assumed by adherents) which gather devotees into a strict network maybe continuing a moral and good exchange with Spirituality. The term Spirituality exclusively bears no weight; in any case, it flourishes deliberately on pieces and pulsates of religion on a mundane scale. Methodologically this paper depends on non-empirical investigation, different writing have been skimmed and checked on. Accordingly an endeavour by the methods for this paper has been made to figure an investigation in the terms of Religion and Spirituality. In addition this article will assist with breaking down the sociological comprehension and will carry on to two isolated but intermingled terms Religion and Spirituality at this point.

This quantitative study investigated the relationship between Chinese university students’ English self-efficacy and English language performance. All the data were collected from a questionnaire of English self-efficacy (QESE) and National College English Test(CET) among 387 university students in China. Principal component analyses showed that the QESE included four sub-dimensions, English self-efficacy in listening, speaking, reading, and writing. Confirmatory factor analysis (CFA) was  
used to test the validity of the scale. The descriptive analysis showed Chinese university students have a moderate level in English self-efficacy. Female students were more self-efficacious than male students by Independent Samples t-test. Pearson product-moment correlation coefficient analysis showed that Chinese university students’ English self-efficacy was significantly correlated with their English language performances. What’ more, Multiple regression analysis showed that speaking and listening statistically significantly predicted English performances among Chinese university students. Pedagogical implications and future researchare discussed at the end of this paper.

Obesity is one of the principle preventable reasons for death. extra than forty % of Iraqis be afflicted by weight problems (obesity). is that it is excessive weight gain with excess body fat. This causes the patient to be exposed to several diseases. (weight problems) is measured in lots of ways, the most crucial of which is referred to as (BMI - body mass index), that's a tool for calculating weight in relation to frame height. someone is overweight if this indicator has a fee of 30 or more.
Methods: The study included healthy natural subjects as a comparison group (control) and they were (61 samples) Including (32) females and (29) males, and their ages ranged (3_15) years, and Patients Group (59 blood samples) were obtained they range in age (2_17) years, Included (35) males, (24) females.
Samples were collected from the patients reviewed at [Al Khayal Hospital].Level of antioxidants was assessed by estimation in the serum convergences of complete cancer prevention agents limit (TAC) by UV spectrophotometric strategy. also, Serum minor components (Zn, Cu and Fe) assessed by Atomic Absorption Spectroscopy (AAS .)
The Statistical Analysis System-SAS (2012) program was utilized to distinguish the impact of contrast factors in study boundaries. T-test was utilized to huge look at between implies. in this examination.
Result: Our study observed significantly elevated concentrations of (TAC)
(p < 0. 01)in the control than patient. Investigation of serum minor components (Zn, Cu and (Fe) found that the mean estimations of Zn, Fe, Cu, were (106.52 ± 0.76) and (70.44 ± 0.76), and (65.85 ± 1.97 ) μg/dl for the patient and (53.73 ± 2.11), (31.16 ± 0.87), and (91.12 ± 3.00) μg/dl for the controls, thusly. There was a significant contrast in minor components the patients and controls (p < 0.01).

The research was aimed to develop a learning media product namely the digital partograph which able to be used during the learning process in case for increasing the learning motivation of midwifery students.
Method: the research applied the quantitative method that designed in cross sectional study. The use of sample was 50 midwifery students in second level and using pre test and post test analysis to test the effectiveness of digital partograph as learning media.
Result: the median score of pretest was 71.09 of those data which can be concluded that the respondent knowledge was included into the sufficient category, after doing learning using the digital partograph media, the partographic filling skills on students had increased into 85.95 with very good category. Meanwhile the significance of p-value was 0,000 < 0,05, it means that the digital partograph as learning media was very effective for developing the partographic filling skill.

Objective: The aim of this systematic review is to review studies on the effect of dates on increasing hemoglobin levels in anemia
Methods: the method used is an electronic database that has been published through the online libraries PubMed and Sciendirect. The keywords used for article searches are based on research questions. Result: a review of six health articles stated that dates are effective for increasing hemoglobin levels. Dosage, timing of administration, type of dates, food intake, a person's health condition should be of particular concern in giving date palm interventions. Not only increase hemoglobin levels, dates can also play a role in increasing ferritin, hematocrit, transferring saturation and serum iron levels in the majority of people.
Conclusion: dates can be used as an additional alternative to increase hemoglobin levels. However, disease or systemic syndrome in each person should be a concern because it can affect the effectiveness of dates in increasing hemoglobin levels.

Soil salinity affects several physiological and biochemical processes in plants. Plant culture of mixed composition and different concentrations of salt treatments were applied for 10 days to detect the response of the salinity tolerant variety of Rice regarding growth, survival, plant height, leaf area, leaf injury, relative growth rate. In vitro superoxide dismutase (SOD), ascorbate peroxidase (APX) and catalase (CAT) activities in the leaves are also screened. Most influenced genotype was IR-64 in terms of growth and dry matter and PB-1 for root length. Maximum SOD activity was recorded in PB-1 followed by IR-64. However, HKR-127 the minimum SOD activity was recorded. APX activity showed large variation in rice genotypes following Sodium chloride (NaCl) treatment. APX activity increased significantly in PB-1 over control in dose dependent manner in all the treated samples. The maximum (25.0%) APX activity was observed in PB-1 at T4 treatment over control. Salt treatment remarkably increased the APX activity in IR-64 up to T3 level of NaCl treatment. In HKR-127 genotype at all levels of treatments there was non-significant increase in its activity. Moreover, Catalase activity in PB-1 increased significantly with all the treatments. The difference among treatments was significant at all levels the highest activity (26.3%) was at T4 level of treatment in PB-1 genotype. IR-64 genotype showed increased catalase activity up to T3 level while in HKR-127 increased non-significantly in CAT at all treatments. The data are discussed in regard to implications of salt stress.

Purposefulness of using the performed families О-445, О-580, О-455 in the genetic and breeding researches for improving of fiber output and the families of О-580, О-455, О-520 to improve the fiber length on the dependence of their genotypes has been presented in this paper. In general, similarity of a high dominance of varieties in the positive indexes on the fiber output and fiber length in combination of various soil-climatic zones was noted.

background: coronary artery disease is the leading cause of death in developing countries and the main treatment strategy includes pci which is usually followed by dual antiplatelet therapy (dapt) with aspirin and clopidogrel. Clopidogrel resistance from genetic polymorphisms incyp2c19 gene involved in hepatic activation of clopidogrel leads to clopidogrel nonresponsiveness and may result in increased adverse clinical outcomes. These polymorphisms in cyp2c19 gene and their impact in mace have been studied in southindian population only in limited number of studies.Methods:we studied 118 consecutive patients (mean age 55.7±10.7 years; 90% male) taking clopidogrel, with angiographically proven coronary artery disease for various genetic polymorphisms incyp2c19 gene. Relationship between loss of function mutation and clinical presentation with higher mace events including recurrent acute coronary syndromes, stent thrombosis were analyzed and genetic analysis. Results: out of 118 patients, 38 (32%) had normal genotype, 23 (20%) had loss offunction mutation( *2) the poor metabolizer type, and 57 (48%) had intermediate metabolizers (*2/*1). Final analyses included 118 patients, with 23 (20%) having loss of function. Seven patients developed stent thrombosis while on clopidogrel; all seven had loss of function mutationin cyp2c19 gene. Conclusion: we observed that the cyp2c19*2 and cyp2c19*1/*2 are the major determinants of clopidogrel efficacy. Acute stent thrombosis was observed in patients carrying cyp2c19*2 variant allele. In patients with an acute myocardial infarction who were receiving clopidogrel, with cyp2c19 loss-of-function alleles had higher rate of subsequent major cardiovascular events in comparison with normal genotype individuals.

The objective of this research is to immediate an efficient strategy, in order to engage in the progression process of Iraqi higher education. The majority of the existing efforts that applied to enhance it, were restricted with the elderly methods of teaching and learning, and did not change the aged traditional framework and methods. The leading objective is to develop our learning methods and reduce the gap with worldwide universities that are progressed and developed learning and education. Executing the MOOCs system, which symbolizes a different appearance by having the qualities of e-learning and lifelong learning, will improve the learning process at the college of Arts at the first university in Iraq, which is the University of Baghdad, and the most significant role is to change it from the procedure of the old traditional learning systems. The plan is to design and perform a complete MOOCs system that competently helps and covers all Iraqi higher education necessities and the UNIVERSITY OF BAGHDAD (COLLEGE of ART), by using the most productive software and methods that minister to our foremost objective. Elameer-Idrus orbital e-education framework was used in the MOOCs designs.

Background: Sarcopenia is a reduction in the rate, strength, and function of skeletal muscle mass that occurs mainly during aging, reduced physical activity, inflammation, and, or as a result of oxidative stress. C-terminal agrin fragment (CAF), procollagen type 3 N-terminal peptide (P3NT), and myostatin circulate biomarkers in elderly people associated with skeletal mass. Interleukin 6 (IL-6) is also a circulating inflammation marker that contributes to the release of hs-CRP and alpha1 antichymotrypsin (AACT).
The objective of Research: To define the differences between certain biomarkers in the sarcopenic subject, the study compared the findings with those of the non-sarcopenic subject that may support awareness of the sarcopenia principles.
Materials and Methods: The study was conducted on 170 participants living in Basra city. The weight (kilogram)/height (meter) 2 equation was used in the BMI calculation. Total cholesterol, triglycerides, LDL-cholesterol, HDL-cholesterol, and calcium were estimated by a fully automated biochemistry analyzer using enzymatic methods. VLDL-cholesterol was tallied by using the Fridwald equation. Vitamin D, IL-6, myostatin, CAF, P3NT, AACT, and hs-CRP were measured by a fully automated ELISA analyzer.
Results: current study parameters included (BMI, total cholesterol, triglyceride, VLDL-cholesterol, LDL-cholesterol, IL-6, myostatin, CAF, P3NT, AACT, and hs-CRP) ) in the sarcopenic subject showed more than the control subject with significantly higher changes (P<0.01)., whereas the parameters included (HDL-cholesterol, calcium, and vitamin D) were demonstrated in sarcopenia group less than 
a control group with significantly higher changes (P<0.01). BMI had a direct correlation with total cholesterol, triglyceride, LDL- cholesterol, VLDL-cholesterol, IL-6, myostatin, CAF, P3NT, AACT, and hs-CRP, with highly significant (P < 0.01). BMI had an inverse correlation with HDL-cholesterol, calcium, and vitamin D, with highly statistic changes (P <0.01).
Conclusions: A findings of the study revealed that obesity serves as a health risk for sarcopenia in elderly adults. High blood levels of total cholesterol, triglyceride, VLDL-cholesterol, LDL-cholesterol, myostatin, CAF, P3NT, IL-6 AACT, and hs-CRP in blood circulation raise the risk for sarcopenia in the elderly. Decrease concentrations of vitamin D, calcium, and HDL-cholesterol increase the opportunity for the elderly to have sarcopenia.

Interventions carried out by health authorities should be aimed at reducing the incidence of STIs in the population, improving the effectiveness of diagnosis and treatment, reducing the likelihood of infection, and changing sexual behavior (T. A. Syrneva, 2002). Given the high incidence of STIs in the population, the low level of prevention against the background of commercialization of the industry, the priority tasks are to improve the efficiency and quality of preventive work in dermatovenerology (I. G. Shakurov 2002, A. A. Kalininskaya, 2004).

In the study, rat brain synaptosomes were used, which are an adequate and convenient model for studying presynaptic processes. L Glutamate activity was judged by the change in the intensity of the fluorescent signal, by the change in the cytoplasmic levels of free calcium [Ca2+]in. The study was conducted according to the Weiler method. Synaptosomes were isolated from rat brain using two-stage centrifugation. The entire isolation procedure was carried out at 4°C. To measure the amount of cytosolic Ca2+ synaptosomes were calculated according to the Grinkevich equation. An increase in the concentration of [Ca2+]in caused by L glutamate, primarily due to the activation of membrane permeability, the movement of Ca2+ into the cell, and the release of Ca2+ from intracellular depots. SP-6 competes with L glutamate for the glutamate binding site of NMDA-receptors. L Glutamate partially reduces the effect of SP-6, which may indicate that part of the external calcium also comes under the influence of SP-6 through the open glutamate binding site and in place calcium channels of the NMDA-receptors. It was revealed that SP-6 increases fluorescence and the level of [Ca2+]in, respectively, in synaptic membranes compared to the control. This data gives, about a possible competition between SP-6 and L glutamate for the site of regulation of the opening of ion channels of NMDA-receptors.

Competency Mapping is a process to identify key competencies for an organization and/or a job and incorporating those competencies throughout the various processes of the organization. The present study attempted to know about the effectiveness of the Competency Mapping at ITES companies in Coimbatore, to know about the employee field and expertise with respect to Competency elements and to know how Competency Mapping align employee behavior with organization strategy and values. The study adopted descriptive research design and collected 120 responses from employees of ITES working in Coimbatore. The Competency Mapping has effect on understanding the company requirements and goals by respondents, laying out clear standard achievable goals by management, motivating the employee to perform their job in better way, identifying the gap in employee job and seek out to overcome, effect on accepting and challenging job by the employee that are achievable in short / long term and has effect on not only setting targets but also monitor effectiveness and efficiency of the employee. Thus, Competency Mapping is highly effective at ITES Companies, Coimbatore. The study suggested to achieve organization goals ,though it is evident from the study that the employees are result focused , there are few employees who have not strongly agreed that they accept challenging job that are achievable in short term or long term basis. This could be fine tuned by the HR department by way of providing motivation and concerned Training and Development to the employees.

Dental cavity is the major problem among adults and children. Early detection of cavity helps to recover the natural functionalities of the tooth. Radiographic examination is used to identify the caries at the earliest stage. Radiographic image collected from the different source may contain noise. Noise should be reduced before doing the further process. Dental tooth has the different layers. They are dental bone, root, pulp, dentin and enamel. Dentist find difficult to identify the caries and its existence in the tooth layers. Segmentation is the technique used in the image processing to extract the region of interest. Layer wise segmentation helps the dentist to detect the caries and also help them to plan the treatment stage by stage. In this paper bite viewing radiography image is taken for segment the images in layer wise. Anisotropic diffusion filter is used as preprocessing technique to filter the noise presence in the image. Contrast enhancement technique is used to improve the quality of the image. Texture information is collected from the image to identify the pixel variation. Canny edge detection is used to detect the edges before segmenting the image in layer wise. Intensity range for the different layers of tooth is observed and the layer wise segmented results are obtained.

We examined 60 children from 5 to 17 years old in the regional endocrinological dispensary in Bukhara in the children's department with diabetes mellitus. The program "Healthy Tooth" was developed according to the following parameters: anamnesis of life, the state of the periodontium, the state of the mucous membrane of the oral cavity, the intensity of the spread of caries, the state of occlusion, the state of hygiene of the oral cavity, the state of the tongue. In all children, we took into account the following survey indicators: blood sugar level, age, hygiene index, PMA index and indices kp, KPU + Kp, KPU. At the same time, a comprehensive study of the oral cavity was carried out, which included the identification of patients' complaints, anamnesis, and a visual examination.

Our results show that the pesticides butylcaptax, dropp and karate are highly toxic pesticides, when exposed to these pesticides, the activity of the enzyme of the P-450 monooxygenase system is disrupted. Also, the research results showed that when poisoning with the above pesticides, ultrastructural, and therefore functional changes in the subcellular components of embryonic hepatocytes occur. When using RAF (plant antioxidant factor), enzyme activity and other indicators are significantly restored, which indicates that RAF has antioxidant properties.

Annotation: In this article, we aim to reflect on the activity that is formed as a result of the application of theoretical knowledge in practice. Social activism is one of the most important aspects of an individual’s activities. It is manifested in the participation of the individual in society and community work; based to a certain extent on the understanding of political and moral identity. Fostering social activism is not only an increase in the level of participation in public affairs, but also the formation of motives that determine the moral orientation of young people. The main pedagogical and psychological conditions of activity are the formation of the student community and each of its members in the form of social attitudes that meet the requirements of society and time - the accumulation of experience. A number of scientific researches on improvement of pedagogical mechanisms of social adaptation of students, development of technologies of preparation for pedagogical activity are carried out in the world. In particular, it is important to improve the professional socialization of students by ensuring their didactic adaptation to higher education, the development of optimal pedagogical conditions for the effective organization of tutoring.
The model of social adaptation of students of pedagogical higher education institution was based on four stages of interaction: interpersonal, interfaculty, interaction with the higher education institution (HEI), professional-value stage (in the first stage of study at the pedagogical higher education institution it is important to overcome the following didactic difficulties Significant complication of the content and volume of educational material (one report contains information on five or six schools, academic lyceums and vocational colleges); new forms and methods of teaching in relation to the school, academic lyceum (lectures, seminars, colloquiums, debates and others); the complexity of the language of the scientific text and lecture material; the lack of skills and abilities of the student to work independently.

Annotation: Folk songs are diverse in form and genre, including alla, song, ashula, yalla, lapar and children's folk songs. For example, the first song you hear in your life is God. The good hopes of mothers are an expression of their sweet dreams about the future of their children. It is one of the oldest and, at the same time, the most popular areas of national music, deeply ingrained in the life of the people. It is no exaggeration to say that in our country it is difficult to find a person who does not have a dutar, doira or other musical instrument at home and does not feel the life-giving effects of music in his life [1].
In order to increase the effectiveness of music culture lessons in secondary schools, the teacher should use a variety of interactive methods in advanced pedagogical technologies, especially computer technology. From time to time it is advisable to listen to samples of melodies and songs on tape or audio and video recordings. recommended. Everyone knows the saying, "It's better to see once than to hear a thousand times." If the oral mastering rate is 10%, teaching will be ineffective [7].
In folk songs, we often see simple and clear comparisons: “Because of the jeweler's attitude to words and images, the idea in each quartet is as dense and mature as the pomegranate seeds. The people do not start a speech from afar, they do not make a profit, they do not stiffen their necks, but they say something and take it from their souls: 'will be sharp. That's why it's easy to remember and spread quickly. Another feature of light, popular songs is that they are sung with melody. People want not only a song to be sung, but also a play to be performed”.[4]

The article is dedicated to the problems of analyzing the models of jaded poetry and their main principles at the beginning of the 20th century.

Background: The objective of the study was to evaluate the effectiveness of montelukast sodium in the treatment and prevention of recurrent obstructive bronchitis in children.
Methods: 80 children aged 1 to 7 years with recurrent obstructive bronchitis were enrolled and randomly divided into 2 groups. Group I (control) included 40 patients who received standard therapy. Group II (main) included 40 patients who received oral montelukast sodium. The effectiveness of the therapy was evaluated by cough relief, sputum separation, RDAI scale, and modified bronchophonography indicator.
Results: Patients who received montelukast had significantly accelerated elimination of cyanosis (by 0.7 days; P<0.05), cough relief (by 0.9 days; P<0.05), disappearance of respiratory failure (by 0.7 days; P<0.05) in comparison with the control group. Positive dynamics of indicator E:I index was observed on average starting from 3 days (P<0.05) until the last day of inpatient treatment (P<0.01) in patients of the main group in comparison with the control group. The anti-relapse effect of montelukast sodium, detected during follow-up of patients for 12 months after discharge, was established, so the frequency of repeated episodes of the disease was 33-59% less frequent in patients of the main group (P<0.01; P<0.001).
Conclusion: Using of montelukast sodium in recurrent obstructive bronchitis in children contributes to significant progress in the dynamics of the disease, leads to a significant decrease in the severity of bronchial obstruction according to the E: I index. The use of the drug causes a decrease in repeated relapses of the disease within 12 months.

Introduction: Local immunological manifestations of chronic hyperplastic laryngitis were investigated on the basis of quantitative determination of epithelial-stromal interactions in the mucous membrane of the larynx of subjects having no respiratory problems. Autopsy examination showed that lymphoid cells were nonuniformly distributed in the laryngeal mucous membrane the pattern of distribution depending on the type of epithelium and its integrity, state of the basal membrane, stroma collagen content, and vascularization. The distribution can be viewed as a characteristic of the adaptive potential of the laryngeal mucosa.
Methods: The object of the study was 21 larynx (16 male, 5 female) of people aged 20-65 who died suddenly from causes not associated with the pathology of the respiratory system (acute heart failure, car accident, etc.). The larynx was fixed in 10% neutral formalin, dissected in the longitudinal direction; for histological examination, preparations were left that did not contain macroscopic signs of pathology. The material, after additional fixation in formalin and embedded in paraffin, was stained with hematoxylin and eosin according to Van Gieson, and a PIC reaction was performed. Statistical processing of the results was carried out using the Student's t-test.
Results: The presence of small lymphocytes in the epithelial layer, and in the stroma under the epithelium of immunocompetent cells at different stages of maturation may indicate that a full-fledged immunological reaction is possible in the laryngeal mucosa.

Annotation. Systemic inflammatory response syndrome is a protective response of the body aimed at eliminating the agent that caused the inflammatory process (infection, trauma, burns and tissue necrosis, etc.). The severity of the response depends on the amount of damage inflicted. This study was conducted to assess the possibility of using the systemic inflammatory response syndrome as an independent predictor in the development of complications of acute pancreatitis. For this, the following clinical and laboratory parameters were studied: body temperature, pulse, respiratory rate and the number of leukocytes in the blood, which were obtained within the first 24 hours after hospitalization and before the development of organ failure. The relationship between the presence of systemic inflammatory response syndrome and the development of organ failure was investigated.

The aim of this research is to investigate the essential elements composition in the cerebrospinal fluid of patients with various outcomes of traumatic brain injury before and after complex treatment with the use of endolumbar and intracystal introduction of ozone and pyracetam in dynamics. Thus, it may be noted positive changes in the metabolism of macro- and microelements in the cerebrospinal fluid of patients

Despite the fact that brucellosis is a particularly dangerous, socially significant endemic infectious disease, to date, there are very few published scientific research on complex treatment, taking into account the pathogenetics of the disease.
Materials and methods. The data of 52 patients, with a diagnosis of chronic brucellosis accompanied by pain syndrome, were analyzed. Based on the received treatment, all patients were divided into 3 groups. The dynamics of treatment was evaluated by laboratory tests, and the perception of pain was evaluated by a 10-point visual analogue scale.
Results. The analysis showed that in all groups there was a positive trend, but the trend of the dynamics was different. The highest rate of improvement in the general condition of patients and reduction of pain was observed in the third group (p-trend<0.0001), which received B vitamins, along with antibiotic therapy and non-steroidal anti-inflammatory drugs (NSAIDs). A lower rate of improvement was observed in the group of patients receiving antibiotic therapy and NSAIDs.
Conclusions. Treatment of chronic brucellosis should be rational and comprehensive, taking into account neurological symptoms, the course, the nature and severity of the pain syndrome. It is advisable to prescribe vitamins of group B, along with NSAIDs and antibiotics, to provide a more rapid improvement in the general condition of the patient.

Background: The objective of the study is to develop a program of scoring for determining the degree of impairment of urodynamics and the preservation of renal function in children with obstructive uropathy on the basis of data from ultrasound - Doppler studies.
Methods: The work is based on the results of ultrasound and Doppler examination of 484 children with congenital obstructive uropathy. In accordance with the obtained data, a point assessment of the degree of impairment of urodynamics and preservation of renal function was carried out in 60 children with obstructive uropathies (30 children with congenital hydronephrosis and 30 children with congenital ureterohydronephrosis).
Results: Analysis of ultrasound and Doppler studies in congenital obstructive uropathy in children by comparing the data, depending on the severity and level of obstruction, revealed 3 degrees of congenital obstruction of the upper urinary tract in children. A comparative study of the urodynamics and state of the renal parenchyma, depending on the degree of obstruction, established a close relationship between the indicators of the functional state of the renal parenchyma and the degree of dilatation and disorders of the urodynamics of the upper urinary tract.
Conclusion: The developed program allows the safe and most informative methods to reliably determine the functional state of the renal parenchyma and the degree of urodynamic impairment in children with obstructive uropathy. Study Registration (ClinicalTrials.gov) ID NCT04605835.

Background: The objective of the study was to study the influence of the combined use of hemodialysis (HD), chemisorption (HS), and metabolic plasmapheresis (PP) for the hemodynamic and defective reduction of intoxication in children with ARF.
Methods: Investigations were performed in 63 children (at the age from 2 to 14 years old) with ARF that was developed as a result of prerenal (hypovolemia, septic shock) and renal (acute glomerulonephritis, pyelonephritis) factors. Depending on the devised detoxification methods, patients were divided into the control group (5) whom it was performed only HD-method and the control group (58) with the use of methods of gravitational surgery, such as HS, HD, and PP.
Results: General clinical presentation in all patients during admission was noted by the significance of intoxication syndrome, signs of respiratory, cardiovascular insufficiencies, in 84,2% of cases it was noted by mental confusion, in 72% of cases it was noted by anemic syndrome, in 78% of cases it was noted by hypoproteinemia and in 93% of cases it was noted by anuria. In 63 cases methods of complex treatment of children were performed once depending on the severity of the condition, a significant degree of the intoxication syndrome, and the level of changes in internal organs.
Conclusion: The influence of sorption methods of detoxification in patients with AKI has a significant advantage over the sessions mono hemodialysis. The corrective effect of complex therapy affects the restoration of organ functions, reduction of intoxication syndrome, and improvement of the clinical condition of patients.

Patient care provided by a coordinated group of doctors, paramedical staff, nurses, technicians, supportive and administrative workers to the people suffering from physical, mental and social ailment. The research paper analysis the patient satisfaction level with the health care system. Patient satisfaction is a highly significant outcome of clinical care in the health care system.A patient expression of the satisfaction or dissatisfaction is a judgment on the quality of hospital care in all its aspects. Patient satisfaction is a indicator for assessment of the hospital. The study reveals various parameter of patient satisfaction from a leading cardiac hospital at Raipur City.

Many of the plants have great potential for the treatment of many diseases and are considered medicinal plants. The main aim of this study is to concentrate on the variety of medicinal plants for further conservation and utility. Chhattisgarh is recognized in India as a well plant diversity state because varieties of plants are found here. Various sections of these plants are used for cure of several diseases. Survey of plant diversity was conducted on campus of the Kalinga University, New Raipur, Chhattisgarh. Total 56 species of medicinal plants which belong to 36 families have been observed Of the 57 medicinal plants, 17 were trees, 20 were shrubs, 16 herbs, 1 gymnosperm and 3 were climbers. It has also been pointed out that the campus of Kalinga University is rich in7plants of Apocynaceae and 6 plants of the family Fabeaceae.

SARS COV-2 is a zoonotic single stranded, positively charged RNA virus belonging to the family of coronaviruses and order of Nidovirales and there are evidences regarding its transmission to humans which state it jumped from bats to pangolins to humans via several mutations. There are several different methods that are being considered for the treatment including Ivermectin, Hydroxychloroquine, carbon quantum dots, plasma therapy, etc. Testing of patients is being carried out by RT-PCR. The gear to fight the virus includes coveralls, goggles, gloves, etc. Soaps, disinfectants and sanitizers have also played a crutial role in the fight against the virus.

Resse has for years been referring to reports on training programs used in European countries, which are the ideal methods for determining training intensity. Therefore, this study aimed to use the method (OBLA) when using the training program for advanced swimmers to see its effect on the anaerobic capacity of anaerobic and glycogenic and enzyme (LDH). (8) They also used several tools, methods and tests, the most important of which was the training program prepared for eight weeks and four training units per week at the time of each training unit (90 - 120) minutes in which the intensity according to the method (OBLA) was used to determine the training time for groups. For selected depending on the distance measured, and upon completion of this training program was conducted tribal posteriori tests and after obtaining the results were processed and about the researchers reached several conclusions was the most important:
- The OBLA training method in the use of severity has a significant effect on the anaerobic capacity of lactic and glycogen and LDH value.
As for the recommendations, the most important were:
- Focusing on the biological side when using the training intensity that accompanies the time of the training unit and the time of the capacity of the training program

Blindness is a growing problem worldwide. The major causes of blindness are glaucoma and diabetic retinopathy. Increased intraocular pressure causes glaucoma. In glaucoma detection, it is very difficult to identify the edge of the optic cup because the image is blurred where blood vessels pass through the optic cup. Current methods do not effectively address the issue of peripheral blurring of the blood vessels surrounding the optic cup. In this paper, it is recommended to automatically detect glaucoma in retinal images using an efficient method. Initially, optic disk and cup segmentation is done by the Convolution Neural Network (CNN) and Modified Region Growing Mechanism (MRG). Then, texture features are extracted from the separated results. Finally, a neural network is used to diagnose glaucoma. The experimental results demonstrate that the proposed approach achieves better glaucoma detection result (accuracy, sensitivity and specificity) compared to few other approaches.

Morphometric measurements of the Tuntong Laut (B.borneoensis) are essential for identification purposes, estimating age, and determining growth rates that are influenced by habitat conditions. This study aims to evaluate the morphometric characters of various generations of sea tails found in several rivers in Aceh Tamiang (Iyu River and along the Tamiang River, Aceh Tamiang Regency).This research is descriptive exploratory research with survey and interview methods. Morphometric measurements of the young age were carried out on hatchlings that were successfully hatched at the Satucita Lestari Foundation information house. Morphometric measurements of adult individuals were carried out on individuals who were caught using traps. Research activities were carried out in August 2019.The measured morphometric characters included carapace length, carapace width, plastron length, plastron width, body height, head circumference, body weight, tail length, foreleg length, and hind leg length. Based on the morphometric measurements of adult females and males, there is a significant difference in size. Meanwhile, morphometric measurements for hatchlings aged seven months (20 individuals), 1.5 years (14 individuals), and two years (4 individuals) had a more excellent value and had an effect on the increasing age of hatchlings.

Preconception care is needed to ensure that the FemaleAge Pairs (PUS) have prepared themselves for the health of the mother and fetus. The aim was to determine the difference in the effect of the use of video health promotion media and preconception booklets on knowledge and attitudes of fertile aged couples. This type of research is a quasi-experimental study with a pretest-posttest two group design with a sample (EFA) of 50 pairs. Quota sampling technique consists of 10 PUS representatives per region. Validity test using Pearson Product Moment correlation with r count> 0.576 and instrument reliability using Alpha Cronbach with alpha results> 0.6. The results of the data normality test for knowledge and attitudes with the Kolmogorov Smirnov Normality Test with a significance value for knowledge of 0.200> 0.05, the data is normally distributed while the attitude is 0.002 <0.05, the data is not normally distributed in value. For knowledge, a paired t test was carried out with a value of 0.000 (p <0.005) with a CI of 95%, so statistically there was a significant difference in the mean of knowledge, then for attitudes a non-parametric analysis was carried out using the Wilxocon test with a value of 0.000 (p <0.005) with CI 95 % then statistically there is a significant difference in the mean attitude. The result of the mean difference between post and pre-treatment knowledge using a booklet of 6.84 (14.96-8.12) while the treatment using video 2.92 (12.44-9.52), there is a difference between booklet and video of 3, 92 in changing respondents' knowledge. The mean difference between pre and post treatment attitudes using booklets was 12.8 (28.88-16.08) while the treatment using video was 4.8 (23.84-19.04), there was a difference between health promotion using booklets and videos by 8 in change the attitude of the respondent. Health promotion using booklets is statistically more dominant than using videos both in changing respondents' knowledge or attitudes. The use of booklets to prepare for pregnancy can be used as early as possible in PUS.

Social media is a source that produces massive amount of data on an unprecedented scale. It serves as a platform for every person to share their perspectives, opinions and experiences apart from just being a platform that gives information to the public who search for information on the disease. As unexpected as the occurrence of coronavirus disease 2019 (COVID-19) was, it has been radically affecting people all over the world, there is a need to analyse the opinion of people on the pandemic COVID-19. This paper focuses on the sentiment analysis of COVID-19 using twitter data. The analyses are based on the machine learning algorithms. This article provides an analysis on how people react to a pandemic outbreak, how much they are aware of the disease and its symptoms, what precautionary measures they are taking and whether or not people are following government’s guidelines etc. Understanding the posts on social media pages during a pandemic outbreak allows health agencies and volunteers to better assess and understand the public's insolences, sentiments and needs in order to deliver appropriate and effective information.

Introduction: Increasing of obesity become endemic problem in childbearing age of women. Therefore, this morbidity frequently found in pregnancy with all of the obesity consequences. Some problems in developing country like Indonesia, especially in our tertiary hospital also experienced burden situation of obesity in pregnancy cases.
Aims:To describe obesity in pregnancy cases and analyze obesity status before pregnancy on obstetric outcome of this morbidity
Material and methods:Retrospective case control study using medical record on singleton pregnancy complicated with obesity in major East Java tertiary referral hospital in one year.
Results:of 1144 deliveries, we revealed 337 cases (29%) of obesity. 246 cases were included and analyzed in this study. Majority of cases were multiparity (72.8%), with age of 31.5±5.6 y.o, BMI of 35.6±4.9 kg/m2 with 19.5% had morbidly obese status.48% of cases had obesity status before pregnancy. Pre pregnancy obesity status not related to Cesarean Section delivery (P=0.07), the occurrence of preeclampsia (P=0.35), gestational diabetes (P=0.97) and fetal macrosomia (P=0.97). Pre pregnancy obesity status related to higher BMI status at delivery (P<0.001) and morbidly obesity condition (P<0.001; OR 5.96; CI 2.58-13.77)
Conclusion:Our study revealed high incidence of obesity during pregnancy. While obesity correlated well with obstetric morbidity, pre pregnancy body mass index status did not associated with obstetric complication in pregnant obesity cases. Higher BMI and morbidly obese pregnancy cases due to pre pregnancy obesity status may contribute to non-significant increase of cesarean section.

Utilization over Internet has been altogether expanded during most recent couple of
decades. People groups saving additional time via web based networking media locales. In
this exploration proposition, we are intrigued to anticipate the character of clients by
assessing their tweets. Up to this point, to accurately measure customer’s characters, they
predictable to get a character test. Th is made it unrealistic to utilize character examination
in plentiful online networking spaces. In this examination proposition, we apply neural
systems by which a client's character can be precisely anticipated through the freely
accessible data on their T witter profile. We will portray the sort of information gathered,
our strategies for assessment , and the AI methods that permit us to effectively foresee
character. This data is essential for organizations to target possible buyers or look for client
suppo sitions in case of enhancement as a business methodology. In this way, this work
examines online networking information to anticipate huge character characteristics, for
example characteristics or qualities explicit to a person. The main strides towards we b
based life locales, raises information size and volume. The measure of information that is
transferred to these person to person communication administrations is expanding step by
step. Along these lines, there is gigantic prerequisite to contemplate the exceptionally
unique conduct of clients towards these administrations. This is a starter work to
demonstrate the client designs and to contemplate the viability of AI prescient displaying
approaches on driving long range interpersonal communication admini stration Facebook.
We demonstrated the client remark patters, over the post on F B Pages anticipated that
what number of comments a position is required to obtain in next H h ou rs.

Physiological, immunogenetic, selection, technological, biotechnological, and other methods to increase the productivity of karakul sheep are used to increase their productivity, as well as biologically active substances that increase the productivity of karakul sheep.

Anti-inflammatory drugs are widely used in medical practice for the treatment of diseases associated with the inflammatory process. However, despite this, many of these medications have the property of causing a variety of side effects and serious conditions. Therefore, the anti-inflammatory activity and toxicity of the new product of phenylglyoxyl acid was studied in rats. Paranitrophenylglioxyl acid thiosemicarbazone, which has shown high activity and low toxicity, can be used as an anti-inflammatory drug.

Chicken pox is one of the leading places in prevalence after acute respiratory infections. The urgency of the problem is determined by the high incidence of chickenpox, the widespread spread of the pathogen, an increase in the specific gravity in the general infectious pathology, and the ineffectiveness of preventive measures implemented in practice (isolation of patients, quarantine). Despite the low incidence of chickenpox in adults, the risk of severe complications and even death is higher than in children. The greatest risk of the dysfunctional course of chickenpox is noted in people with immunodeficiency. This is characteristic, first of all, for patients with HIV infection and patients with chronic diseases (diabetes mellitus, autoimmune diseases, bronchial asthma, chronic hepatitis, systemic diseases of the connective tissue).
The aim of the study was to conduct a retrospective analysis of the clinical and laboratory features of the course of chickenpox in children and among the adult population of the Samarkand region, as well as to offer practical measures for the prevention of disease in practical health care.

Today, acute respiratory infections, including viral ones, occupy a leading place in the pathology of childhood. One of the frequent and severe manifestations of acute respiratory diseases in young children is acute (primary and recurrent) stenosing laryngotracheitis (ASLT). The problems of acute laryngotracheitis are caused not only by its high prevalence, the possibility of severe complications and death, but also by the tendency to recurrence. No less important is the features of the formation of both acute and recurrent laryngotracheitis. In the pathogenesis of acute stenosing laryngotracheitis (OSLT) in children, one of the leading clinical manifestations is the syndrome of endogenous intoxication. These are, first of all, destructive processes, as a result of which an excessive amount of intermediate and final metabolic products accumulate in the body, which have a toxic effect on the most important life support systems.

This article is devoted to the study of the stationary flow of a viscous fluid in a flat channel with permeable walls. As is known, in a pulsating flow in pipelines, a pressure wave propagates through its walls, which is called a pulse wave. This wave, as it moves away from the initial cross section, gradually weakens and practically attenuates at the ends. In the present work, stationary flows of a viscous fluid in a plane channel with permeable walls are considered to be sufficiently long for the channel. The problems are solved and calculation formulas for determining the longitudinal and transverse speeds are obtained. Formulas are also found and numerical calculations are made that determine the change in pressure and fluid flow in the direction of the main stream for various values of the permeability coefficient. It is shown that at lower values of the coefficient of permeability, the pressure is distributed along the flow according to linear laws, and the fluid flow rate remains almost constant along the channel length. Other values of the permeability coefficient, it is characteristic that with an increase in the permeability coefficient of the pressure distribution differs significantly from the linear distribution, with the maximum deviation in the middle of the channel. The fluid flow rate with an increase in the permeability coefficient increases several times in the initial section compared to the fluid flow rate, in the same pressure drop in the flow of a viscous fluid in a flat channel with impermeable walls.

This study discusses the issues of the ordering form of the soil cover structure of non-irrigated and irrigated zones of the modern delta of the Amudarya River. The relationship between soil and relief elements with structures has been studied comprehensively.

It was proved that the studied new phytopreparation Lesbachol under experimental conditions exhibits a pronounced protective effect on the gastric mucosa. And so, under the influence of lesbachol, the area of ulceration decreases by 58.5%, and in the group of the studied drug to glycerol - by 32.7%. The results showed that lesbohol with small punctate ulcers compared with the control group was reduced 2.6 times, with large ulcers it was reduced 2.8 times, with striped ulcers 2.6 times, the total number of ulcers decreased 2.6 times ... Therefore, Lesbokhol, as a potential highly effective anti-ulcer agent, is of practical interest and can be recommended for the prevention and treatment of gastric ulcer and duodenal ulcer.

One of the most pressing problems in modern gynecology is the problem of chronic inflammation of the appendages. Every obstetrician-gynecologist has to deal with a complaint of pain in the lower abdomen in women every day. About 39% of women experience pelvic pain caused by inflammation of the uterine appendages periodically, while 12% of patients experience pain for at least 5 days every month, and another 12% suffer from persistent pelvic pain [2]. Chronic pelvic pain occupies a special place among the variety of clinical manifestations of gynecological diseases and is considered by most researchers as one of the leading symptoms of inflammatory diseases of the pelvic organs: chronic salpingitis and oophoritis, pelvic peritoneal adhesions, chronic endometritis. However, the presence of a "routine" gynecological pathology cannot always explain the development of pain in the lower pelvis. Pelvic pain is an indication in 12% of all hysterectomies. For this reason, the aim of our study was to optimize the treatment of chronic inflammatory diseases of the uterine appendages to improve the quality of life and prevention of pelvic pain. The object of the study was 100 women with chronic salpingoophoritis complicated by pelvic pain, who were divided into three groups according to the method of treatment. During the study, we used, along with general clinical research methods and examination for sexually transmitted infections, special research methods, such as: studying the intensity of pain on the VAS scale, bacterioscopic and bacteriological examination of vaginal contents, ultrasound scanning and Doppler studies, estradiol, progesterone, testosterone, FSH, LH, DHEAS-S, TSH, prolactin and cortisol in the blood serum, the content of prostaglandins F2α, E2 and growth factors in the serum. In addition, the level of immunoglobulin A (IgA), the concentration of the main cytokines (IL 1β, IL6) in the blood serum were determined. The resulting material was subjected to automated statistical processing. After the examination, the patients received the necessary treatment, which included antibiotic-anti-inflammatory therapy (ceftriaxone, doxycycline, metronidazole), 20 procedures of pharmaco-physiotherapeutic intravaginal electrotherapy with the drug Glutoxim in an amount of 1 ml of 1% solution, intravaginal ultrasound therapy, synbiotic Bifiten. Based on the results of the data, the effectiveness of the use of the developed pharmaco-physiotherapeutic method (91%) was proved in comparison with intravaginal ultrasound therapy (74%) and, especially, drug therapy (40%).

14 species of myrcomycetes of the class Leotiomycetes have been identified on decorative trees in the southern part of Uzbekistan. Species of the genera Uncinula, Phyllactinia, Leveillula, Microsphaera, Erysiphe are obligate parasites, and Marssonina, Melasmia, Rhytisma are considered facultative parasites and causative agents of dangerous diseases in trees. The species Rhytisma ulmi Fr., Melasmia populinae Rehm were first identified in the mycobiota of Uzbekistan. During a scientific study, 10 species of ornamental trees were found to be infecting representatives of the Leotiomycetes class. Including Salix dahynoides Vill. - 3, Ulmus pumila L. – 2, Populus alba are found in pairs, and in the species Acer negundo L., Sophora japonica L., Fraxinus sogdiana Bunge., Catalpa bignonioides Walt., Salix alba L., Quercus robur L., Robinia pseudoacacia L. one at a time.

UzPITI-201 cotton variety seeds were sown under a transparent film on March 15-25, 155, 4 thousand seedlings per hectare were left and mineral fertilizers were applied at N180Р125К90 kg/ha rate and also in the variant irrigated in the optimal 70-75-60% order compared to LFMC, i.e. due to the soil conditions formed under the positive influence of the transparent film, the highest yield was 41,4 ts/ha, an increase in the cotton fiber technological quality was observed, along with the additional cotton yield cultivation of 5, 6-9,3 s per hectare compared to the control options planted in seeds double row and single row in the usual open method

This article highlights the notions of an informed economy, the importance of information and communication technologies in the development and development of the national economy.

62 children and adolescents with obesity accompanied by arterial hypertension were examined. It was revealed that the development of myocardial hypertrophy is affected by body weight, blood pressure,vasoconstriction processes, as well as insulin resistance and atherogenic dyslipidemia. These parameters serve as early markers of myocardial hypertrophy.

In total 60 children were examined, over 22 of mature newborns are born from healthy parents , 20 newborns are born from mothers with OPG-gestosis, and 18 newborns born from mothers with OPG-gestosis combined in chronic pyelonephritis . It was identified that in children with complicated course of disease, inheritability was rarely aggravated, the disease was followed by epiphenomenon , in the main group of newborns were observed a low level of of glomerular filtration, tubular reabsorption of acidogenesis, which were
associated by a disproportion of the phospholipid spectrum of erythrocyte membranes due to the increased blood activity and LPO

The study of the adrenaline content in the blood and the manifestation of a stress state in patients using psychoactive substances (PAS) with HIV infection is one of the key indicators in the provision of medical and psychological assistance and the development of appropriate psychotherapeutic measures. When carrying out these activities, it is necessary to take into account the level of adrenaline and the severity of stressful conditions, in order to be able to overcome stress and adapt to the diagnosis.

Malignant neoplasms of the reproductive system of women are the most frequent in the structure of oncological diseases. Their total total share is more than 38% in the structure of the overall incidence of malignant tumors. According to the WHO, 550 thousand cases of newly diagnosed cervical cancer (CC) and more than half of deaths from this pathology are registered annually in the world. In the Republic of Uzbekistan in 2012, 1323 patients with cervical cancer and 623 deaths from this disease were registered. In recent years, there has been an increase in the incidence among women of fertile age. Increasingly, the disease occurs between the ages of 28-45 years. In the Republic, about 60% of cervical cancer is detected in the I-II stage of the disease.

The regional spatial plan is one of Indonesia's main future goal for development that upholds the prosperity of the people, spesifically in Province of Papua, hence the issuance of the Papua Provincial Regulation on it’s spatial plans, are expected to realize a sustainable spatial planning in Papua and as well restoring the environment’s balance considering the problem of decreasing number of forest areas in Papua that caused by coal mining activities. Therefore, an action of making strict and clear restrictions must be made, if there are no such strict restrictions and arrangements, it eventually will result in environmental damage that will be experienced by our future generations. The effects of enviromental damage which will be experienced by our future generations if this so, are already contradictory with the realization of the principle of intergenerational justice.

One of the aims of land registration is to ensure legal certainty for the holder of a certificate of land rights. However, in reality, people with sufficient evidence and data can still decide the legality of a certificate of land rights although they have met the cumulative elements in Article 32 paragraph (2) PP No. 24 of 1997 concerning land registration through the State Administrative Court. This article aimed to determine the ratio decidendi judges in deciding a case of certificate submission after the expiration of 5 (five) years pursuant to Article 32 paragraph (2) PP No. 24 of 1997 concerning land registration. The research method used by the writer was normative juridical. The results of this study indicate the ratio decidendi of the Panel of judges in deciding a case of certificate submission after the expiration of 5 (five) years pursuant with Article 32 paragraph (2) PP No. 24 of 1997 concerning land registration.

Lycopene has extensively been shown to inhibit tumor growth in nude mice bearing Breast. However, high tumor-suppressive Lycopene dosages encumber the development of oral controlled-release formulations because of a short biological half-life (< 2 h), poor absorption, low aqueous solubility, and extensive first-pass metabolism. Here, we present the design, fabrication, optimization, characterization, and biologicalevaluation of estrone-conjugated lycopene -loaded gelatin nanoparticles for targeting estrogen receptor- positive breast cancer MCF-7 cells. Gelatin nanoparticles (GN) were uniformly compact sized, stable
at physiological pH, and showed good drug entrapment efficiency.

Background/Aim: Sarcopenia is a syndrome characterized by progressive loss of muscle mass and strength with a risk of adverse clinical outcomes such as physical disability, reduced quality of life, and death. Oxidative stress and inflammatory processes are known as factors that trigger sarcopenia by releasing the catabolic stimuli of IL-6. Based on this we study the dynamics of interleukin-6 (IL-6) in elderly sarcopenia in Wahidin Sudirohusodo Hospital Makassar.Method: This study was an analytic cross-sectional design conducted at the Geriatric Polyclinic of Wahidin Sudirohusodo Hospital, Makassar in March-June 2020. The assessed variables were degree of sarcopenia (probable sarcopenia, sarcopenia, dan severe sarcopenia) based on The European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria, age, sex, number of comorbids, and IL-6 levels examination. Statistical analysis was performed by descriptive statistical calculations and frequency distribution as well as the Independent-t statistical test, and Anova test. Results: Studied from 82 subjects (51 females, 62.2%) with the mean of 68.95 years of age. The prevalence of probable sarcopenia was 40.2%, sarcopenia 8.5%, severe sarcopenia 6.1%, and normal 45.1%. IL-6 levels were found to be significantly increased according to the severity of sarcopenia (normal, 52.81 ng/; probable sarcopenia, 67.47 ug/L; sarcopenia, 135.36 ng/L; and severe sarcopenia, 287.99 ng/L). Based on age, IL-6 levels increased significantly with age (60-74 years, 63.28 ng/L; 75 years, 139.35 ng/L). Based on the number of comorbids, IL-6 levels increased significantly according to the number of comorbids (1-3 comorbids, 52.86 ng/L; 4 comorbids (120.84 ng/L). Conclusion: In the elderly subject, IL-6 levels increases according to the severity of sarcopenia. IL-6 levels also increases with age, and the number of comorbids.

The recent deadly outbreak of Novel coronavirus (2019-COVID) associated with human to human transmission and severe human infection has been recently reported from the city of Wuhan in Hubei province in China and gradually the number of infected people around the globe increased in fatality ratio. This study aims to identify the historical background of the coronavirus family that is already affected the civilization and animals. This study will overview the overall literature published on the Coronavirus and vaccination development with nature of viruses. For that, the Scopus database and web of science database is selected to analyse the published literature. The research methodology is followed by the strict screening process of the PRISMA statement framework (2015) for the screening and quality assessment. Final 93 studies are included for the systematic literature review. The most important and critical part of the study is about the classification of the past literature on the topic of coronavirus. severe acute respiratory syndrome coronavirus (SARS), Middle East Respiratory Syndrome Coronavirus (MERS), bovine coronavirus, canine coronavirus and feline coronavirus are the major classifications discuss in the literature. This study contributes to the literature by providing an elaboration of a descriptive mapping of the existing literature on the studies of Coronavirus pandemic that is a greater challenge for humanity in the current circumstances. Finally, the future of the world after the 2019-COVID is more challenging and important for vaccination development and health care sector.

This research aimed to investigate the relationship between customer’s attitude and mobile payment among Malaysian customers. There are three research objectives. First to identify the consumers’ related issues which effect the mobile payments among Malaysian Customer. Second objective is to investigate the relationships between, payment culture, ease of use, usefulness and security. finally, to identify the main consumers’ concern that influencing the mobile payment feasibility in Malaysia. In this research, the researcher carried out a survey among the young public to access the performance of mobile payment services available in Malaysia. Besides, the direct opinion from the consumers is able to enhance the insight of the service providers. In conclusion, mobile payment feasibility is important to realize Bank Negara Malaysia (BNM) strategy which is Malaysia becomes a cashless society by 2050.

This study investigated the consumer’s attitude factors that influence continuous usage of mobile shopping applications in Malaysia. The study used self-administrated questionnaire to collect data from 384 respondents using online form who had previous experience on using mobile shopping applications to purchase products. The findings show that privacy, security, perceived usefulness, perceived ease of use and electronic words of mouth are positively related with the consumer’s attitudes to continuously use the mobile shopping application. This study enhances the researcher’s understanding on how the perceived usefulness, privacy and security, electronic words of mouth and perceived ease of use in influencing the consumer’s attitudes to continuously use the mobile shopping applications. This study extends the application of expectation-confirmation model (ECM) and technology acceptance model (TAM) which can provides the theoretical understanding on the various factors that influencing consumer’s attitudes to continuously use the mobile shopping applications. The managers should focus on those factors in order to encourage more people for using the mobile shopping application to purchase the products.

The use of passive cooling techniques combined with a low cooling load may result in good thermal comfort. The passive design responds to local climate and site conditions to maximize the efficiency and health of building users while minimizing energy use. It generally believed that passive cooling is healthier, cheaper and sustainable. However, it is not certain where there is provision for the active cooling system; users of such building may prefer passive cooling hence. This study aims to elicit users preference for passive cooling in the senate building chamber of Modibbo Adama University of Technology (MAUTECH) Yola; by administering questionnaires to the users available at the time of the research work. A total of 50 questionnaires were administered, 45 were retrieved and evaluated using 5-point Likert ordinal scale (5 = Strongly agree; 4 = Agree; 3 = Undecided; 2 = Disagree; and 1 = Strongly disagree). Weighted mean values were calculated based on which decisions were made: When the weighted mean value is not less than 3.5, it was decided as agreement; and disagreement when weighted mean values were not more than 2.4. The result showed users preference for passive cooling in the senate building chamber of Modibbo Adama University of Technology (MAUTECH) Yola and users awareness about issues of sustainability. It was recommended that passive cooling strategies should be incorporated in future building designs to boost energy conservation and reduce greenhouse gas emissions.

In the domain of Internet of things Reconstruction of images from compression is very important. Transferal, store house and receiving of a set of different images in different technologies such as wireless, bigdata, machine learning, medical etc. is playing very important role to get desired output. This paper gives more information about Design of a Reconstruction from compression for Dynamic Magnetic Resonance Images Imaging. In this paper author has worked extension of segmentation and compression work on IPPFRFT and IDWT. Hunch responsiveness to the images of dynamic nature becomes heir to the various parameters from the Pseudo-Polar Trajectory of PPFRFT methods. Peak Signal to Noise Ratio, Structural Similarity Index Measures, Mean Square Error etc. take place performance parameters evaluated by simulation and comparison results commonly masterful as compare to existing methods in terms of reconstruction and compression.

This paper examines the situation of Internally Displaced Persons (IDPs), the causes of displacements and the trends of migration in Juba. The specific factors that create displacements and migrations are identified by some expert respondents and the analysis of the trend over some time of the independent era to date was done. Two locations of Hai-Zandiya and Gureii in Juba were selected for the study. Up to twelve (12) policy actors within the United Nations agencies, funds, and programmes; International and National Non-Governmental Organizations were randomly selected and interviewed with a total of ninety-eight (98) respondents. Data was collected using well-structured questionnaires and Key Informant Interview (KII), using the Delphi techniques through the aid of Google docs for two rounds of questionnaire administration and interview sessions with key informants. The findings identified a series of factors that triggers migration, categorized as Man-made and natural (Economic, political, social and environmental factors. The study, therefore, recommends the need to encourage inclusive arrangements in coordination, policy formulations, humanitarian and development nexus to support the reconstruction as well as efforts to minimize the perennial displacements and migratory trends. The trend was shown according to major classification, specific factors, the causes and finally the resultant effects. Policy recommendations were preferred to best manage the crises by the actors within the government and the local and international partners

This paper aims to identify the challenges and threats to the information security of cloud computing, which is considered one of the most important technologies in recent decades. Cloud computing provides many virtual services that can be managed and accessed by users through the web and user interfaces. It also enables the users to store their information that can be easily accessed globally. Despite the advantages of cloud computing, there are numerous challenges and threats to the users and service providers that may directly or indirectly affect the cloud computing system as a result affect its information security. Acritical review approach has been adopted as a method to identify the knowledge gaps in the literature. Severalstudiesrelated to the information security challenges of cloud computing have been reviewed and critically evaluated. The critical review approach described in this paper resulted in a set of important information security challenges of cloud computing thatmust betaken into considerationby the users and service providers. Among the most important of these challengesare data encryption, network security, confidentiality, data privacy, malware, Authenticity, databreach, and the challenge of identity and access management.The study recommended the necessity to discover moreinformation security challenges of cloud computing and to take the challenges discussed in this paper into account in order to protect the data and information of the organization and maintain its performance.

The relationship between higher education (HE) and the world of work has been discussed for the past few decades, in terms of, among others, contribution of higher education to the labour market, in the form of manpower. The market requires that higher education graduates fulfil certain competencies and in fact they considered more important in the recruitment process than the degree itself. In Industrial Revolution 4.0 which is characterized by trends such as Internet of Things, robotics, virtual reality (VR) and artificial intelligence (AI), the way people live and work has changed and because many jobs are predicted to be lost due to, among others, automation, it is important that HE comprehends the changing nature of the work and map the labour market condition. With the challenge of the 4th Industrial Revolution, it is of utmost necessity to prepare students during their study time, 3-4-year period. This paper will discuss the importance of higher education institutions in mapping the labour market in their efforts to prepare graduates with competencies for the 4.0 industrial revolution. Secondly this paper will discuss the importance of extracurricullar activities in higher education level because when designed carefully, extracurricular activities will become very effective for students to gain certain competencies

The quantity of Non Resident Indians and their quantum of settlements in the Tamil Nadu state have been expanding at an astounding rate. The studies led by the Dept.of Economics and Statistics, Tamil Nadu and the Kerala Migration Survey (KMS-2016) by Prof. Irudaya Rajan and Prof Zachariah (CDS, Kerala) uncovers that settlements sent by the NRIs gives mass migration backing to in any event one-6th of the all out general public of the Chennai City. Tamil Nadu state accepting a disturbing amount of settlement of NRIs yet it is certain that these commitments are not gainfully channelised by concerned government. The current point is predominantly chosen to dissect the Investment Attitude and Pattern of NRIs in India particularly Tamilans in Chennai City. As per official information, NRI deposits in Tamil Nadu specially Chennai city have now crossed the wizardry figure of Rs 2.23 lakh crore, expanding rapidly by over 29% from Rs 104,864 crore to Rs 123997 lakh crore toward the finish of 2018-19. Settlements from NRIs are the establishment stones of the Tamil Nadu economy. The reason for this investigation is to distinguish the relationship of the elements that influence the Investment Attitude and Pattern of NRIs in India with special reference to Chennai City.

The aim of the study was to study the clinical and diagnostic features of cystic fibrosis in children in Uzbekistan. The study included 120 patients with cystic fibrosis at the age of 0 months. up to 14 years old, who were inpatient treatment in the department of pulmonology, pathology of early age and gastroenterology. In children with cystic fibrosis, the main clinical symptoms of the bronchopulmonary system were: cough, shortness of breath, oral wheezing, lethargy and loss of appetite. Upon admission to the hospital, the general condition of the patients was most of all regarded as severe. The most common causative agents of the disease exacerbation were S. aureus - 32%, Str. pyogenus - 26%. Based on the results of the study, the frequency of mutations in the CFTR gene and their influence on the nature of the course were determined. A significant role has been revealed for the 4 most common gene mutations in Uzbekistan, CFTR-F508del, CFTR-2143delT, R709X, Y569D.

The aim of the study was to study the effectiveness of the use of protected cephalosporin III generation Extum in the treatment of community-acquired pneumonia in children. The study included 100 children with community-acquired pneumonia at the age from 1 to 15 years, who were observed and treated in the department of pulmonology. In the process of complex clinical and laboratory examination of children, biochemical, microbiological and immunological research methods were used. Microbiological studies have shown that in children with community-acquired pneumonia, S. Pneumonia occupies a significant place in the etiological structure and accounts for 42.0% of cases, a high sensitivity of pneumococcus to injectable cephalosporin of the third generation has been established. When included in complex treatment, protected cephalosporin of the third generation Extum leads to a decrease in the frequency of repeated acute respiratory infections and their complications by 2.2 times, the frequency of recurrent bronchitis and pneumonia by 1.7 times, which indicates a high therapeutic effectiveness of the proposed treatment

In connection with the continuing chemicalization of agriculture in the republic and the increasing intensification of industrial production, the danger of chemical pollution of objects of the human environment, disturbance of the ecological balance and their negative impact on the health of the population increases. As you know, in the conditions of Uzbekistan, the main sources of environmental pollution in rural areas are large-scale use of pesticides and mineral fertilizers, and in industrial cities - emissions from various industrial enterprises; in some cotton-growing regions, there is a combined pollution of the environment with pesticides, mineral fertilizers and industrial emissions

The article presents information about the hygienic state of the oral cavity, the state of periodontal tissues, the level of hygienic knowledge and measures of therapeutic and prophylactic measures among workers of silk-winding production. The object of study was 97 workers of the alkaline-winding industry "Bukhara Brilliant Silk", who are exposed to industrial noise, as one of the harmful production factors, also the dustiness of the air in working rooms in various workshops and, in terms of importance, harmful, production factors are microclimatic conditions, at the age of 29 59 years. The control group consisted of 44 employees of the administrative and managerial apparatus, whose work process excludes the impact of factors of the working environment. The results of the research revealed the total prevalence of diseases of hard tissues of teeth (99.1%) and periodontal disease (100%) among workers of the alkaline industry "Bukhara Brilliant Silk", a high prevalence of diseases of the oral mucosa - 58.7%, a low level of oral hygiene and hygiene knowledge. There is an obvious need to develop a targeted prevention program, including a comprehensive - individual, professional oral hygiene and health education.

In understanding the spread and control of infectious diseases, mathematical modelling has become an important instrument. The epidemic disease COVID-19 caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) has affected the population of almost all the countries. This disease is highly contagious and spreads through one to one contact (physical closeness)[5]. It spreads through the air in the form of tiny droplets transmitted by the breath, cough, sneezing, or even verbal contact of an infected person [19]. Being highly contagious and mortality rate, the number of confirmed cases and deaths are alarmingly rising. By routinely washing hands, keeping unwashed hands away from the face, avoiding public areas, and maintaining social distance, the various strategies to curb the spread include ensuring adequate hygiene. As a consequence, aggressive measures are required to control the spread of infectious diseases, particularly those for which both vaccines and treatments are available. Besides, combating the occurrence of a disease is always easier than treating it. This paper formulates and solves numerically the modified SEIR model with vital dynamics includes an additional compartment called Vaccination with an assumption that the vaccination will provide lifelong immunity. This assumption is feasible as the immunity can be extended through booster vaccinations in due course. The basic reproduction number is calculated and the stability of the model is discussed using the Lyapunov method. The importance of the various epidemiological parameters related to the Vaccination compartment model is discussed numerically also.

The article outlines the issues of improving and developing higher education by solving the problems of integration and continuity, the implementation and structure of an integrated lesson, interdisciplinary integration and continuity.

The article discusses the problems of accelerating hydrothermal treatment in the preparation of wheat grains grown in dry climates for varietal grinding. In it, the effect of activated water on the natural mass of wheat grain was studied experimentally. The differences in changes in the natural mass of wheat grain under the influence of activated and drinking water are theoretically explained.

TBI is a complex pathophysiological process that includes primary and secondary brain damage that affects the structure and function of the nervous system. The incidence of TBI is 3 times higher than the population growth and the cost of treatment is more than 33 billion euros per year. Recently, there has been a growing interest in hypertonic saline solutions, which act in the same way, exerting an osmotic effect, increasing the movement of water from the tissues into the circulatory system. The present study was to study the efficacy and safety of using 7% NaCl in the treatment of intracranial hypertension in patients with isolated traumatic brain injury in the adult population. This group consisted of 35 patients with isolated traumatic brain injury at the age of 21-80 years (42.6 ± 13.2 years).

The article illustrated the geochemical barriers in the soils and the radial double-sided geochemical barriers formed in the irrigated meadow soils of Central Fergana. The migration and accumulation of chemical elements and substances in these barriers are illuminated on the basis of geochemical spectral formulas.
And also, the effect of geochemical barriers on the yield of agricultural crops (cotton) was studied.

Conditions for the analysis of albendazole by spectral methods: UV-spectrophotometry and thermal desorption surface ionization spectroscopy (TDSIS) were developed. Qualitative and quantitative analysis of albendazole isolated from biological fluids was performed under the developed analysis conditions. According to the results, 38.74% of albendazole was isolated from blood by UV spectrophotometry, and 43.00% from urine, while 47.46% from blood and 64.72% from urine by TDSIS.

Relevance: The high prevalence, high risk of social maladjustment as a result of the consequences of acute cerebrovascular accident and, accordingly, one of the main causes of mortality gives cerebrovascular pathology a special status, as evidenced by numerous publications. the task was to identify in the studied patients the entire spectrum of clinical manifestations corresponding to the lesions of the brain structures supplied by the blood vessels of VBD and to determine the presence of a statistically significant dependence of clinical manifestations of COPD. As well as the identification of risk factors and their influence on the rehabilitation of patients with stroke in the vertebrobasilar system.
Patients with IS in VBD and COPD - 62 people (group I) - 29 men and 33 women aged 50 to 74 years (59.8 ± 5.8). Patients with IS in VBD - 64 people (group II). Of these, 31 were men and 33 were women aged 51 to 80 years (62.4 ± 5.4). All patients received traditional treatment in the most acute and acute periods of IS, patients with COPD received COPD treatment in parallel with traditional IS therapy. in group I, BMI averaged 29.3 ± 5.8 kg / m2, in men - 28.9 ± 6.3 kg / m2, in women - 29.9 ± 5.1 kg / m2 (the difference is not significant, p = 0.58), while 11 patients (17.7%) had a normal BMI, 1 patient (1.6%) had a body weight deficit, 26 patients (41.9%) had preobesity, 15 patients (24, 2%) had first degree obesity, 9 patients (14.5%) had second degree obesity. Accordingly, preobesity or obesity was recorded in 50 patients of group I (80.65%) (Figure 3.3)
And in group II, BMI averaged 28.7 ± 6.1 kg / m2, in men - 27.8 ± 5.7 kg / m2, in women - 30.1 ± 5.6 kg / m2 (the difference is not significant, p = 0.6), while 17 patients (26.6%) had a normal BMI, 3 patients (4.7%) were found to be underweight, 29 patients (45.3%) had preobesity, 8 patients (12 , 5%) had first degree obesity, 7 patients (10.9%) had second degree obesity. Accordingly, preobesity or obesity was recorded in 44 patients of group II (68.8%). In patients of group I, among the clinical manifestations of IS in PBS, ataxia prevailed, which occurred in 35 patients (56.5%), including hemiataxia, which occurred in 20 patients (31.3%). Paresis and paralysis of the limbs were detected in 31 patients (50%). Complaints about a subjective feeling of unsteadiness, instability in an upright position, and imbalance occurred in 25 patients (40.3%). Dysarthria also occurred in 25 cases (40.3%). Nystagmus was detected in 22 cases (35.5%), rotational dizziness (vertigo) - in 20 cases (32.3%), depression of consciousness - in 21 cases (33.9%). Symptoms such as hemianopsia and ophthalmoparesis occurred each in 14 cases (22.6%). Sensory disorders were detected in 12 patients (19.4%), autonomic disorders - in 8 patients (12.9%), diplopia - in 8 patients (12.9%), dysphagia - in 7 patients (11.3%) , aphasia and headache - 6 patients each (9.7% each), dysphonia - 7 patients (11.3%), confusion and visual agnosia - 4 patients each (6.5% each), respiratory failure - 3 patients (4.8%). There were also 2 cases (3.2% each) of amnesia, ignorance syndrome and a feeling of generalized weakness.

The article considers the procedure for regulating the activities of private employment agencies, as participants in the migration process, analyzes the participation of civil society institutions and association of compatriots living abroad in protecting the rights and legitimate interests of citizens of Uzbekistan within the context of COVID-19, and puts forward proposals for improving legislation in this area.

In this article, the author analysed the role, significance and need for the correct determination of the motive for the pre-crime abandonment based on the analysis of a judgment, and also developed scientific conclusions on this issue.

Treatment of acute pancreatitis is a complex and far from final solution of the problem of emergency surgery of the abdominal cavity. First of all, this is due to the complexity of the pathogenesis and sometimes unpredictability of the course of the disease. Despite some success achieved in recent decades in conservative and surgical treatment, the mortality rate in acute pancreatitis is still quite high and, according to various authors, ranges from 5 to 74 %. Moreover, the share of purulent complications among the causes of death of patients accounts for 57-80 %. Postoperative mortality in acute aseptic necrotic pancreatitis is 21-25 %, in infected patients-35-40 %.
Abstract: Treatment of acute pancreatitis is a complex and far from final solution of the problem of emergency surgery of the abdominal cavity. First of all, this is due to the complexity of the pathogenesis and sometimes unpredictability of the course of the disease. Despite some success achieved in recent decades in conservative and surgical treatment, the mortality rate in acute pancreatitis is still quite high and, according to various authors, ranges from 5 to 74 %. Moreover, the share of purulent complications among the causes of death of patients accounts for 57-80 %. Postoperative mortality in acute aseptic necrotic pancreatitis is 21-25 %, in infected patients-35-40 %.

This article compares and analyzes the state of changes in natural geographical processes in Mirzachul region under the influence of the Sardoba reservoir until 2018, before and after the construction of the reservoir.

The measures taken by the health system are of great importance for the preservation and protection of women's reproductive health . At the same time, the integration of traditional medicine with the modern health care system also plays an important role in improving the health of the population. The article given result and analyzed on the views of women of reproductive age in the area using questionnaires. Keywords.Women's reproductive health, health care system, integration of traditional medicine, population health.

In today’s world one can witness numerous processes related with the violation of democratic values and the interference with the public opinion. In a time, where the advocates of democratic tide constantly trying to use all resources they have to increase the role of the public authority over the government, it is wrong to try to govern the public with autocratic leadership methods and anti-democratic measurements. Today’s world is also witnessing a new kind of mechanisms of formation of public opinion, which was not beheld before. The new kinds of socio-political advertisement serve for this purpose and political authorities are achieving their aims with these means.
Many developed countries of the world emphasizing the importance of the studies focused on the achievement of political goals through the implementation of new socio-political techniques in the formation of public opinion. In this respect, an ordinary person, an un-socialized group, attracting attention through a pressing problem, the use of the popularization technologies with the aim of increasing the popularity of candidates in social networks and bringing the “human factor” to a higher degree acquire a greater importance. Therefore, many leading research institutions of today’s world give more attention to the problems of creating a new system of formation of public opinion, the synthesis of the process of politicization of social advertisements, and the maintenance of transparency of political interest groups.

62 children and adolescents with obesity accompanied by arterial hypertension were examined. It was revealed that the development of myocardial hypertrophy is affected by body weight, blood pressure, vasoconstriction processes, as well as insulin resistance and atherogenic dyslipidemia. These parameters serve as early markers of myocardial hypertrophy.

In total 60 children were examined, over 22 of mature newborns are born from healthy parents , 20 newborns are born from mothers with OPG-gestosis, and 18 newborns born from mothers with OPG-gestosis combined in chronic pyelonephritis . It was identified that in children with complicated course of disease, inheritability was rarely aggravated, the disease was followed by epiphenomenon , in the main group of newborns were observed a low level of of glomerular filtration, tubular reabsorption of acidogenesis, which were
associated by a disproportion of the phospholipid spectrum of erythrocyte membranes due to the increased blood activity and LPO.

Scientists have been researching for a long time, where they have found evidence of a connection between “Lactobacillus - Caries”. According to the results of some countries, the qualitative and quantitative composition of lactoflora of the oral cavity is already known in the norm and case of diseases caused by disbiotic conditions of the mouth. This article presents the results of the quantitative and qualitative composition of oral lactoflora of women of fertile age, the state of biological properties of each particular representative and their impact on cavities formation, which can explain the microbiological etiology of cavities. Each of the following indicators was statistically processed and compared with the results of foreign countries.

Adhesive disease of the abdominal cavity, complicated by acute intestinal obstruction, is one of the most difficult diseases of the abdominal cavity in terms of treatment and diagnosis. The urgency of the problem is determined by the complexity of prevention and treatment of the studied complication, the widespread increase in surgical activity, the expansion of indications for performing operations of extended volume and combined interventions for diseases of the abdominal cavity and retroperitoneal space. Analysis of the literature shows that acute intestinal obstruction occupies one of the first places among urgent pathology of the abdominal cavity in terms of the frequency of complications and fatal outcomes. An increase in the number of patients, the severity and recurrent nature of the disease, difficulties in diagnosis, unsatisfactory immediate and long-term results of treatment of patients with adhesive small bowel obstruction, as well as a high percentage of disability determines the relevance of the chosen topic.

the article deals with issues related to the contract of trust management of property and problems of its development in the Republic of Uzbekistan. Attention is drawn to the stage of development of the legal basis of the contract of trust management of property in the world and in the Republic of Uzbekistan. Mention the elements that reflect the trust, according to the author “in the clear”, given the conclusion that the civil law point of view, trust management associated with the introduction of common law system the rules of the Institute of trust with adaptation to the system of continental law, and its basis is an agreement involving two or three parties.

The article identifies the role of the service sector in the socio-economic development of the country, based on the relationship between the dynamics of development of the service sector and the increase in incomes of the population employed in it. The development of the service sector and the improvement of its sectoral structure have proven to be one of the strategic directions of increasing the income of those employed in the sector.
The results of the study show that the income of employees in the service sector is significantly lower than in the material production sector, which does not meet the essence of the industry in the transition to post-industrial development, its role and importance in the national economy. based on. Therefore, it was noted that the problem of equalizing the level of material production sectors on the basis of a sharp increase in wages of employees in the service sector has become more urgent.
In solving this problem, it is important to increase the volume of services, optimize its sectoral structure, effectively stimulate human capital, strengthen the link between wage incomes and the results of business entities. recommendations developed.

The article examines topical problems of improving the quality of education and its key role in achieving the goals of accelerated socio-economic development of Uzbekistan. However, over the years, a huge number of problems have accumulated in the country's educational system, which significantly reduce the prestige and efficiency of the education system. The article reveals the reasons that gave rise to negative trends in the field of education, analyzes the active efforts made by the state to eliminate them, substantiates their inadequacy to solve the acute problems of economic growth in the country. In it, a radical improvement in the quality of education is considered as the most important way to solve the pressing problems of labor migration of the population and employment of the unemployed.

Asian service industries have grown up in last decade to a great extent. Asian economy is performing better in many countries over last few decades. Service industry is contributing significantly to the Asian GDP. The developed countries of the world are creating most of the jobs from service industries compare to other. The contribution in GDP of developed countries from service sector is about 60 to 80%. Service sector is one of the major contributors in economy of the European and American countries. The success of the industry is depends on various factors. Satisfaction of the customer is one of the major factors in service industry to be successful. Authors have presented the methods of enhancing the efficiency of service industries. The analysis of service industries is carried out depending upon the survey data and presented in this paper.

In order to assess the dependence of the thyroid status of the organism on the functional state of the monooxygenase system of the endoplasmic reticulum of hepatocytes in sexually mature male rats, induction and inhibition of the monooxygenase system of the liver by its inductors and inhibitors was caused. As inducers, we used known induction drugs - benzonal (benzobarbital) and zixorin (flumecinol), and as inhibitors a chemical compound - cobalt chloride and a blocker of histamine H2-receptors - cimetidine. Benzonal was administered orally at a dose of 50 mg / kg body weight for 3 days, and zixorin was administered at a dose of 40 mg / kg body weight for 4 days. Cobalt chloride was administered once intraperitoneally at a dose of 30 mg / kg of body weight, and cimetidine was administered orally at a dose of 100 mg / kg for 10 days. It was revealed that during the induction of the monooxygenase system of the liver by its inductors - benzonal and zixorin, there is an increase in the content of thyroid hormones - triiodothyronine and thyroxine in the blood against the background of no change in the level of thyroid-stimulating hormone. When the monooxygenase system of the liver is inhibited by its inhibitors - cobalt chloride and cimetidine, an increase in the content of thyroid hormones - triiodothyronine and thyroxine in the blood is also observed, but against the background of a statistically significant decrease in the content of thyroid stimulating hormone. It is concluded that there is an indirect relationship between the functional state of the monooxygenase system of the liver and the thyroid status of the body.

At present, all over the world, the problem of increasing the antibiotic resistance of pathogenic microorganisms is very urgent. More and more complex mechanisms of antibiotic resistance of microorganisms are being deciphered, which creates prerequisites for the search for new antibiotic substances from natural sources. One such poorly studied source is endophytic fungi synthesizing biologically active compounds of various structures and biological effects. The potential for use in medicine, pharmaceutical and agricultural practice of fungal endophytic metabolites is very rich and has not yet been fully studied. The endemicity of plants in some regions of Uzbekistan, combined with a sharply continental climate, determines the unique biodiversity of endophytic fungi of medicinal plants. For the first time, researchers (prof. T.G Gulyamova at al.) picked out more than 200 strains of endophytic fungi from 30 medicinal plants growing in various ecological niches on the territory of the republic, and studied their antimicrobial and anticarcinogenic potential.
Keywords: endophytic fungi, plant endemicity, isolation, identification, extracts of secondary metabolites, producers of biologically active substances, interaction with the plant host, antibacterial, antifungal and cytotoxic activity, vincristine, vinblastine.

This paper presents the relevant aspects of marketing research on soft and transdermal drugs on the market of the Republic of Uzbekistan.
A structured content analysis of soft and transdermal drugs was carried out by comparing quantitative and qualitative characteristics according to the criteria: dosage form, pharmacotherapeutic group, origin, far-abroad countries, CIS countries, domestic.
Revealed a relatively greater number of registered drug forms ointments, suppositories. It is shown that antifungal agents of domestic producers 7.8%, CIS countries –9.4%, foreign manufacturers 9.8% prevail on the market; antiseptic - domestic - 16.3%, CIS - 7.6%, foreign - 3.2%; anti-inflammatory domestic production is 19.2%, CIS-11.17%, foreign 32.8%.
A not small list of pharmacotherapeutic groups of ointments is known due to poor absorption, old technologies lose their relevance. Gels have replaced, and what is relevant for the development and introduction into domestic production of new or well-known drugs in the form of gels.
In the territory of the republic, gels are mainly registered and used abroad (36%), when domestic manufacturers produce only 5% of the soft drugs produced. Gels are of particular interest because of their structural, mechanical, and physical properties.
It should also be noted that some pharmaceutical groups, such as immunosuppressants, drugs for the treatment of eryctile dysfunction, hepatoprotectors, androgens and its synthetic analogues, drugs that promote normal scarring, corticosteroids account for a small% and are registered only by foreign manufacturers, and then in a small amount i.e. not registered in the CIS countries and domestic manufacturers.
The results indicate the feasibility of further research to assess the prospects of creating and introducing new topical drugs, in the form of soft drugs (gels, suppositories), new and a combination of those already produced by domestic manufacturers.

. Purpose is to conduct quality control and standardization methods of a combined action suppository containing benzketasone and papaya extract in accordance with modern requirements of good manufacturing practice.
Methods of natural and accelerated storage are used to study the factors affecting the stability of suppositories during storage (type of base used, temperature and storage time). It was revealed that under the conditions of a refrigerating chamber at a temperature of + 3-50 ° C, the studied suppositories practically did not change the quality indicators during 24 months of storage. The type of base slightly affected the change in the physicochemical parameters of the Benzpap and Benzpap 10 suppositories.

In recent years, research on the pharmacokinetics of medicinal substances has become of exceptional importance both in terms of increasing the efficiency and safety of drug treatment of various diseases. In the development of a drug, the determining factor becomes the need to ensure a uniform release of the drug from the form-forming component, which is established in in vitro and in vivo experiments. Pharmacokinetic studies of the non-steroidal anti-inflammatory drug phenylglyoxylic acid derivative fensulcal in rectal dosage form suppositories have been studied. The studies were carried out according to the developed methods for the detection and release of fensulcal in biological fluid. According to the dynamics of release in in vivo experiments , it was found that the maximum concentration of fensulcal in the blood was reached after 1 hour. The study of the parameters in the in vitro and in vivo experiments led to the need to calculate the degree of their correlation. A high degree of correlation was established. The results on the value of the correlation coefficient indicating the existence of a direct relationship between the intensity of release in experiments in vitro and its entry into the blood in vivo after rectal administration of suppositories to animals.
To assess the effect of a drug and its routes of administration on the rate of absorption of drugs and bioavailability, formalization of their pharmacokinetics was carried out in the form of a one- or two- part model . To assess the pharmacokinetics of Fensulkal suppositories, model-independent parameters were calculated taking into account a 2-chamber model. The results indicate that the maximum amount of fensulcal in the blood is observed 1 hour after administration (P <0.05 ). After reaching the maximum concentration, fensulcal is distributed in organs and tissues at a speed of 504.03 / min. Elimination of the drug proceeded at a lower rate, K β , h -1 = 0.0182. The constants of the fensulcal transition from the central to the peripheral chamber and vice versa are calculated. From the presented data follows K 21 >> K 12 , which indicates the absence of drug accumulation in the tissues.

Uterine fibroids is the most common benign gynecological disease, the pathogenesis of which is not fully understood. We examined 152 women in the II clinic of the T ashkent Medical Academy. The saturation of the body with vitamin D (25 ( OH ) D ) and its relationship with concomitant obesity in patients with uterine fibroids and healthy women were studied . In less than half of women with symptomatic myoma, deficiency and severe deficiency of vitamin D prevails with concomitant obesity of varying degrees . Studying the relationship between vitamin D deficiency and excess body weight in this pathology makes it possible to predict the development of the disease, the nature of the course and the risk of possible complications.

Research objective: to study the possibility of using the method of chromato-mass-spectrometry combined with IR-spectrophotometry in the forensic chemical analysis of trace amounts of unknown poisonous and superpotent substances.
Material and methods. For the forensic study a material evidence – an empty glass and a used empty disposable syringe were provided by the judicial and investigation authorities, taken from the crime scene. The following tasks were set before the experts: to find traces of any substances in the glass and syringe and reveal the origin of the poisonous and superpotent substances; determine the name of the substances.
Results. During the conducted analysis using gas-liquid chromatography with the mass spectrometric detector and IR spectrophotometry, the complex method was developed for the forensic chemical examination of pregabalin and tramadol trace amounts on the object-carriers. The research established the analysis parameters such as retention time, molecular and fragmentation ions, their intensity, individual fragmentation of pregabalin and tramadol. IR spectra were obtained with characteristic passbands of functional groups related to pregabalin and tramadol structures.
Conclusion. The research proved that application of the complex methods, which have high sensitivity, speed and simplicity in use, affords to quickly and accurately identify unknown substances in the composition of micro-objects.

Objectives: There have been taken rheological indices of the ointment and gel containing dry extracts obtained from Curcuma Longa L. and Ferula asafetida L.
Materials and Methods: According to rheological indices are one of the main quality normative of the ointment and gel, there have been studied their elasticity, viscosity and plasticity properties. There have been conducted experiments on the instrument Rheotest-2 (Germany) by using cell system “cylinder-cylinder” S/S1 (cell constant z=5,6) at the temperature 25 о С, 40 о С, 55 о С.
Results: According to the results of the researches, there have been determined that viscous stream activity energy of the ointment is 26,6 kJ / mol, viscous stream activity energy of the gel is 23,3 kJ / mol, and it is coincided with viscous stream activity energy level of the ointments and gels.
Conclusion: There has been decided to consider that these contents are perspective according to the rheological properties of the suggested ointments and gels.

Our studies have suggested that the mechanism of action of the sum of flavonoids (liquid extract "Hemostat") from pylori, pylori, nettle and nettle in a ratio of 1: 1: 1 on the blood coagulation process is associated with its effect on the number, adhesion and platelet aggregation, as well as the retractive ability of platelets. It was revealed that the liquid extract "Hemostat" has a pronounced hemostatic effect and in this respect it is noticeably superior to the known preparation of the liquid extract of the shepherd’s bag.

Research objective: to conduct a quantitative determination of sodium diclofenac and vitamin B-12 in new lyophilic drug Cobafen using modern physicochemical methods of analysis.
Materials and methods. During the research we used the samples of commercially available substances of mecobalamin chloride produced by Apex Medichem Ltd. (India), D-mannitol manufactured by Shandong Tianli Pharm. Co. Ltd. (China) and polyvinyl pyrrolidone (PVP) produced by Merck (Germany), as well as chemical reagents by Sigma-Aldrich (USA) and Hi-Media (India). For spectrophotometry analysis we applied a UV-1800 double-beam spectrophotometer (Shimadzu, Japan) and Agilent 8453E single-beam spectrophotometer (Agilent Technologies, Germany). Besides, the study was carried out under conditions of reverse phase HPLC (Agilent 1280 gradient HPLC chromatograph (Agilent Technologies, USA) and LC-20 (Shimadzu, Japan)).
Results. Conducted 5 independent experiments for each formulation and each freezing mode showed that D-mannitol is the additive agent of choice. Besides, lyophilizates produced using D-mannitol corresponded to the indicated quality attribute. When analyzing mecobalamin by HPLC, it was established that the method of choice was PP with methanol: buffer solution (26.5:73.5), the optimal concentration in the analysis of mecobalamin is 2 mg / ml.
Conclusion. It was established that sharp freezing condition is the most preferred due to the saving in production cycle time. The proposed HPLC method for quantitative determination of the active substance in the drug, validated by all validation parameters, is included in the pharmacopoeial monographs of JURABEK LABORATORIES JV LLC

Comparative study of a new combined 4% hydrophobic ointment and psilo-balsam in experimental skin allergy of Guinea pigs.
Experimental allergic dermatitis was caused by method of P. M. Zalkan and E. Ievleva using 2,4-dinitrochlorobenzole on Guinea pigs using a 4% combined ointment of a thick extract of Bidens tripartitae and root of licorice and a comparison with drug psilobalzam. It was found that a combined 4% hydrophobic ointment, a thick extract of Bidens tripartitae and a dry extract of licorice root is more effective in the treatment of contact allergic dermatitis than the antihistamine drug psilo-balsam.

Intrauterine growth retardation is an important problem in pediatrics, as it is an integral indicator of intrauterine dysfunction.
Purpose: to study the features of the clinical and functional state of the cardiovascular system in newborn children born with various types of intrauterine growth retardation.
Material and research methods: 70 newborns were examined. All children were divided into 2 groups: the 1st (main) amounted to 50 newborns with IUGR, of which: 1a - with the symmetric version of IUGR - 25, 1b - with the asymmetric version of IUGR - 25 children, in the 2nd group (comparisons) 20 premature infants without IUGR were included. All newborns underwent an echocardiographic examination of the heart.
Results: on the basis of clinical and instrumental studies, the features of the clinical and functional state of the cardiovascular system in newborn children born with various types of intrauterine growth retardation are presented. In children who had different types of intrauterine growth retardation, significantly significant features of cardiac activity and morphological and hemodynamic parameters of the heart at birth were proved. Children with a symmetric variant of IUGR are characterized by a slowed heart rhythm, which was recorded significantly more often than in children with a symmetric variant of IUGR.

The study explores theory of relativity of acid levels with nephritic function, moreover as its role as a prognostic marker of cardio tube risk in chronic excretory organ diseases within the course of variable regression analysis, taking into consideration the adjustment of potential risk issues, the amount of uric acid was found to be a major factor influencing calculable capillary vessel filtration rate. The results of this study showed that elevated humor uric acid levels are related to the next risk of kidney malfunction.

The aim of the study was to review the features of the functional state of the kidneys in patients with cardiopathy, betting on the presentation of the components of the metabolic syndrome. For the research we examined 197 male patients with chronic heart condition (CHF) of ischemic genesis of II-III functional class (FC) in line with NYHA. Metabolic syndrome in patients with chronic heart failure HFmrEF exacerbates impaired renal function, which has developed together of the most pathogenetic links in chronic heart condition. it's been established that because the metabolic syndrome progresses (attachment of T2DM to other components of the metabolic syndrome), the phenomena of functional kidney failure increase. Evidence of the importance of the metabolic syndrome within the nature of the clinical manifestations of chronic coronary failure HFmrEF is that the established dependence of the identified disorders on the severity of the metabolic syndrome.

To research the short-term and long-term effect of coronary artery stenting on renal function. In patients with coronary heart disease within 3 months after endovascular revascularization-preserving renal dysfunction, despite the normalization of creatinine concentration.

The research describes the concept of healthiness of the physical activity for patients with chronic kidney disease, moreover because the effect of 12-week physical training on physical activity in patients with chronic disease of stage 3-4 who are on a low-protein diet.
At the identical time, patients with variety of chronic diseases aside from CKD also suffer from poor physical performance and muscle atrophy, but more evidence has been accumulated of the positive effect of exercise in such patients [3].
Increased physical activity is related to improved ability to perform everyday activities, professional tasks. Therefore, regular exercise is usually recommended for such patients within the DOPPS study, patients who performed regular physical activity had the next quality of life related to health, good fitness and sleep quality indicators, with fewer patients with limited physical activity and lack of appetite [4].

The gastrointestinal tract is an active dynamic system that implements a number of important life support processes [30,2,57,87,203]. Impact of emergency situations on structures performing barrier-protective functions remain largely unexplored. In recent years, ideas about the role of the epithelium of the digestive tract have expanded, significant, and it has been found to be significant in loss of renal function [7,8,2]. Therefore, the epithelium of the gastrointestinal tract should be considered not only as a selective barrier to penetration of toxic substances into the interstitium, but also a key link in decontamination endogenous intoxication. The barrier-protective function of the digestive system is associated with border tissues, which have a strict morphological organization. These phenomena are as diverse as nature physical, chemical or biological aggression on the internal environment of the body can be various. Process layering data is important for practical use of the phenomenon of "layered defense", when stress or damage increases secretion and secretion, increases proliferation and desquamation of the epithelium, as well as migration of neutrophilic leukocytesfrom the bloodstream to the epithelial layer. [22].Under normal conditions, the gastrointestinal tract is considered a balanced ecosystem where there is a certain habitat - physical space. The state of the mucous membrane of the small intestine, the main participant in the absorption processes and excretion of metabolic products deserves the most attention. It has been found that oral administration enterosorbents (Karbovit and Polypefan) in intact rats does not cause mucosal changes membrane of the jejunum and ileum and does not affect the state of enterocytes. However, in some in some cases, ES enhances the secretion of goblet cells, especially in the apical part of the intestinal villi [22]. At the same time, a relatively large number of Pannet cells were registered in crypts, and Lamina the propria around them contains many immune-competent plasmocytes and neutrophils. Electron microscopic examination of various parts of the small intestine showed that when mercury chloride injected into rats, the number of microvilli of enterocytes was shortened and decreased, and the number mitotically dividing cells increased. In this case, there is a pronounced vacuolization of enterocytes observable; vacuoles glow with electronics and contain flocculent material. Side cells emptied, Pannett cells contain a small amount of secretory granules. Characteristic feature of the effect of mercury poisoning on the mucous membrane of the small intestine is inhibition of the reaction of cells of the connective base. The protective barrier of the mucous membrane of the gastrointestinal tract consists of three levels: luminal, epithelial and connective tissue.

Purpose of the study: to check some indicators of the immunohemogram in patients with community acquired respiratory disorder on the background of CKD.
Materials and methods. one hundred twenty patients with community-acquired respiratory disorder were examined: forty patients with respiratory disorder (group Pn) and eighty respiratory disorder, that developed against the background of chronic nephrosis (group Pn+ CKD). The management cluster (CG) consisted of twenty healthy individuals. The study found that the amount of leukocytes was exaggerated within the Mon + CKD cluster by 162.24% than in the CG (p <0.001), within the Mon cluster 263.14% on top of within the CG and twenty seven.79% than within the cluster Mon + CKD (p <0.001). In patients with Mon, the quantitative relation of the amount of neutrophils to lymphocytes significantly exaggerated (p <0.001 compared with the CG and also the Mon + CKD group), reflective the shift of the formula to the left, and within the Mon + CKD cluster this quantitative relation remained unchanged, despite the increase within the absolute variety of leukocytes. In patients with respiratory disorder with background CKD, a marked increase in T-lymphocytes was determined because of a population of CD8 and CD95 cells (p <0.001 compared with CG and also the Mon group). a rise in IgM concentration prevailed within the pneumonia cluster, and a rise in immune serum globulin prevailed within the PN + CKD cluster (p <0.001).
Conclusion. Respiratory disorder related to CKD is related to associate active general inflammatory response involving non-specific immunity and also the depletion of its cellular part, as well as activation of immunity because of chronic inflammation and chronic matter stimulation.

Objective: to investigate the characteristics of the clinical course of community-acquired pneumonia in patients with constant kidney infection. The ponder included 120 patients with pneumonia: 40 patients had no history of renal pathology (group M), 80 patients endured from inveterate kidney infection (GFR for 3 months some time recently the improvement of pneumonia 30-60 ml / min / 1.7 m2, group M + CKD ). Confirmation of the determination was carried out on the premise of chest X-ray, the detailing of the conclusion included deciding the sort of pneumonia - croupous or central intersecting.
In a comparative evaluation of the X-ray picture within the explored groups, it was famous that in patients with pneumonia against the foundation of CKD, lobar and central intersecting pneumonia with a huge penetrate volume were altogether more frequent (p <0.001). Within the flow of follow-up, the larger part of patients (78 out of 120 patients, 65%) appeared positive clinical and radiological elements, 20 patients (16.67%) appeared no critical elements, and 22 patients (18.33%) had clinical and radiological elements. negative. Negative clinical and radiological flow was more frequently watched within the group of patients in whom pneumonia developed against the background of CKD (p <0.01).

This article describes the features of the clinical course of the disease, assesses the quality of life, diagnostic criteria for the disease, modern classification and tactics of hypotensive therapy in patients with chronic kidney disease, Pathogenetic mechanisms of chronic kidney disease, Correspondence of the stages of chronic kidney disease to the ICD-10 coding.
Various modern studies are described to assess the quality of life of patients using the SF-36 questionnaire, which includes 8 scales: physical functioning, role functioning due to physical state, pain intensity, general health, vital activity, social functioning, role functioning due to emotional state and mental health.

The point of the study was to decide the impact of hereditary polymorphism on the impacts of endovascular revascularization in patients with coronary heart disease, angina pectoris FC III-IV.
The research included 158 patients with coronary heart disease with angina pectoris of FC III-IV pressure (ladies 34 -21.52%). Upon consideration within the ponder, all patients experienced: Echocardiography, TLC, genotyping of 6 genes of the system of natriuretic peptides, coronary angiography and stenting of the coronary courses. For follow-up examination, patients were welcomed after a year. The study included echocardiography, TLC, stress echocardiography.
Hereditary investigation permits foreseeing the drawn out impact of coronary supply route stenting: the overall danger of coronary illness movement (as stress-incited ischemia) in patients with minor alleles is 2.12 occasions higher than in patients with prevailing homozygotes for qualities of the natriuretic peptide system.
The current examination found that the presence of minor alleles of qualities of the arrangement of natriuretic peptides is related with a more prominent pervasiveness of atherosclerotic injuries of the coronary bed, the movement of underlying and useful rebuilding of the heart. What's more, the presence of minor alleles lessens the drawn out adequacy of coronary revascularization, both in the part of coronary atherosclerosis and in the part of the utilitarian condition of the myocardium (movement of LV dilatation and preservation of the sleeping myocardium).

Recently, the growth of non-alcoholic fatty liver disease has been actively discussed in domestic and foreign literature. In Uzbekistan, the incidence of non-alcoholic fatty liver disease increased from 27.0% in 2007 to 37.1% in 2014 and ranked first among liver diseases.

This study is dedicated to the study of the effect of changes in the active energy of the parathyroid glands on the morphological tension of bone tissue formation. Experimental modeling of hypoparathyroidism in laboratory rats (n = 30) was carried out and the dynamics of morphological changes in the process of bone tissue ossification was analyzed. On the basis of the results of morphological methods of study, the dynamics of the formation of tubular bones was revealed, and the patterns of ossification of bone tissue against the background of hypoparathyroidism were also set. As a result of the study, it was shown that it differs from the usual histological picture of hypoparathyroid individuals in the zones of elevation, just the basal layer of chondrocytes are vacuolated. The emergence of young osteoblasts is oriented by the spaces; they are located according to the type of multidirectional architectonics

Research objective: to synthesize new carbamate derivatives - ɣ-bromopropargyl ethers of carbamate derivatives for their further application as initial compounds in the synthesis of simple and asymmetric diacetylene ethers of carbamate derivatives.
Materials and methods. Infrared spectra on UR-20 and UR-10 spectrometer (“Carl Zeiss”, Germany) were applied at 3600-500 cm-1, in the form of tablets pressed with KBr. For determination of purity of the obtained compounds, a thin layer chromatography was used. As an adsorbent we used a layer of AI2O3 of the II activity degree, and an iodine vapor as a developer.
Results and Discussion. Using the method of bromination of propargyl ethers of carbamate derivatives, ɣ -bromopropargyl ethers of carbamate derivatives were obtained, used in the synthesis of simple and asymmetric diacetylene ethers of carbamate derivatives. The optimal conditions for their synthesis were established in the process of studying the effect of various factors. Besides, antifungal and herbicide activity of the synthesized compounds was studied and analyzed. Compounds with high antifungal and herbicidal activity were determined.
Conclusion. Convenient methods were developed for obtaining new ɣ-bromopropargyl ethers of carbamate derivatives during the investigation. New simple diacetylene ethers of carbamate derivatives were synthesized by the reaction of interaction on the basis of propargyl ethers and ɣ-bromopropargyl ethers of carbamate derivatives. New asymmetric diacetylene ethers of carbamate derivatives were synthesized by carrying out the reaction of interaction based on propargyl ethers and ɣ-bromopropargyl ethers of various carbamate derivatives.

The article presents the results of our own research on the detection of the cumulative effect of the studied food additives of different classes in the comparative aspect. The results obtained allowed us to conclude that the flavor identical to natural and artificial flavor with prolonged ingestion can cause pathological processes in the liver, as well as lead to over excitation of the nervous system, followed by a sharp inhibition.

Application of three-stage therapy of giardiasis in 250 children with CHB, using MACMIROR®, Albendazole, and Metronidazole at the second stage of effecting the parasite and its elimination from the organism, provided achievement of clinical-biochemical remission in 91.1%, 72.5% and 52,5% cases, and parasite elimination in 93.3%, 32.5% and 60.0% cases, respectively. It should be noted, that in the conditions of administration of Trichopolum, in spite of the high rate of G.Lamblia elimination, the therapy was associated with the expressed hepatic toxicity, making recommendation of it for that category of children impossible. Thus, the first line agent for a specific therapy of giardiasis in children with CHB is MACMIROR®, due to its efficacy and safety.

Nilotinib (TasignaTM) a tyrosine kinase inhibitor is used in the treatment of chronic myelogenous leukemia and other tumor entities, this study aims to investigate nilotinib effects on fertility in male albino mice three groups each with 7 male albino mice selected, one control group, and two groups administered with 80mg/kg and 120mg/kg respectively for 3 months and serum levels of testosterone, FSH, and LH were measured by ELISA kits and statistically analyzed. Histological sections from testes prepared and stained with H&E stain and evaluated histopathologically. Statistically significant reduction in the mean of serum testosterone and FSH were seen in treated groups compared with the control group with no significant differences regarding LH concentration; variable histological changes noted in comparison with the control group ranging from mild changes in most cases with more severe atrophic changes in 1 case from the group(2) and 2 cases in a group (3).Our results showed statistically significant changes in testosterone and FSH levels in mice administered with nilotinib with variable deleterious histopathological changes

The given article provides a description of the new 52nd most important ornithological territory of Uzbekistan (IBA). Inventory, monitoring and development of measures for the conservation of IBA are one of the modern international approaches to the territorial protection of biodiversity. The Society for the Protection of Birds of Uzbekistan has been developing this direction since 2005 as a partner of the World Association for the Protection of Birds “Bird Life International”.

An analysis of the literature on the theory and methodology of physical education reveals that in the theory of sports (wrestling, etc.) and in separate articles, the authors have described explosive power as a physical quality.
The manifestation of explosive force is the mechanism of its activation. As the burst time of the muscle decreases, the intensity of the bursting force increases. However, the intensity of the explosive force can also be increased by increasing the magnitude of the absolute force of the muscle.
Summarizing the above points, it can be concluded that the study of the features of the methodological basis of the formation of explosive mobility in athletes in fast-paced sports plays a certain role in solving important vital issues in sports.

Among the complex of anthropogenic factors, one of the leading places is occupied by the "water factor" associated with pollution of water sources, shortcomings in water purification and disinfection. Discharge of insufficiently treated and untreated wastewater into watercourses predetermines abnormal changes in their chemical composition and degradation of biocenoses.
Background and Aim: Municipal wastewater contaminated with organic and nitrogen-phosphorus-containing compounds, as well as bacteria and viruses, also contribute to the pollution of water bodies. The main factor affecting the change in the quality indicator of water bodies is municipal wastewater. In the treatment facilities of Bukhara, about 20 thousand m3 of wastewater, which will lead to a change in the chemical and biological composition of water. At the same time, there is no complete picture of the distribution of algae and their role in determining the ecological and sanitary state of biological ponds of the treatment plant in Bukhara, which prompted us to study these important problems.
Material and Methods: Processing of the collected algological material was mainly carried out in the laboratory of algology and hydrobotany of the Institute of Botany of the Academy of Sciences of the Republic of Uzbekistan and was also partially processed at the Department of Botany of the University of Bukhara. The physicochemical composition of wastewater in biological ponds was determined by the generally accepted methodology of A. S. and Yu. Yu. Lurie.
Conclusion: According to our observations, representatives of all systematic groups of algae developing in a particular reservoir participate to varying degrees in the processes of self-purification of wastewater. Even species of the same genus are characterized in different ways. This indicates the need for comprehensive and deep floristic studies of the natural algal population of water bodies used as biological ponds - reservoirs, sedimentation tanks and filtration fields.

The aim of this study was to assess the state of indicators of the hemostasis system of blood and saliva in patients with CGP concomitant CHF. 109 people aged 40 to 60 years, with signs of chronic generalized periodontitis (CGP) concomitant CHF were examined. In accordance with the objectives of the study, 3 groups were formed: Group I - 50 patients (39 men and 11 women) with chronic generalized periodontitis on the background of AH and IHD, Group II - 34 patients (22 men and 12 women) with CGP on the background of AH and IHD combined adentia, group III - 25 patients (15 men and 10 women) with periodontal pathology (CGP), without diseases of the cardiovascular system (CVS). Revealed hyperhomocysteinemia and an increase in the procoagulant activity of saliva and blood, which is a consequence of not only CGP, but also atherosclerotic process, in which a thrombogenic threat is created due to the involvement of endothelial cells of the oral mucosa in this process.

The composition of nutrients in the fruits of amaranth with different color coat was studied. The protein composition of amaranth seeds was defined. The lipid complex of various types of amaranth has been determined. The oil from amaranth seeds by the method of raw material extraction was obtained. It has been established that amaranth oil approximates to cotton oil interms of unsaturated fatty acids content.

Quality and basic physical-chemical, technological characteristics of wheat grain of “Chillaki” variety have been studied in this work. Quality indicators and physical-chemical characteristics of the new wheat grain of “Chillaki” variety have been established, which allowed determining the possibilities and recommendations for its cultivation in the salted soil-climatic conditions.

The article deals with the conceptual field analysis in Linguistics. The author discusses the conceptual field, the analysis of the conceptual field, and the linguoculturological analysis of the text in this way or scheme. The author also cites his own analysis, focusing more on the practical side of linguoculturological research. This show how topical is the research, which is the comparative study of conceptual fields in different languages. The author considers that this article will be of certain interest for those who investigates Cultural Linguistics, Cognitive Linguistics and Discourse analysis.

Currently, in the information technology society, the higher education system of the Republic of Uzbekistan has risen to a new level. Competitive highly qualified personnel trained in higher educational institutions have a special place in increasing (exceeding) the country's prosperity and welfare of the population. In this regard, the article presents scientific proposals for the modernization of the higher education system, their foundations and information on the expected results.

The chemical composition of growing Silybum marianum in the south-eastern part of Uzbekistan: the amount of silymarin and flavonolignans was studied. Silybum marianum has almost no contraindications and is rich in chemical composition, which positively affects the body and human health. It can normalize the work of a number of body systems in a short time and strengthen the immune systematic, and this directly depends on the amount and concentration of biochemical compounds contained in its chemical composition. We analyzed the dry extract of the seed in HPLC and paid special attention to the number of Flavolignans contained in it. It has been studied that the full effect of flavonolignans contained in Silybum depends on its chemical concentration in terms of importance and stable antioxidant performance. This article describes the results obtained when the taxifolin, Silibin, Silidianin and Silikristin flavonolignans after the results in HPLC were continued in mass spectrometry.

A wide range of scientific research is being carried out in the world to predict and detect early manifestations of caries in children during orthodontic treatment, as well as to optimize the effectiveness of diagnostic and treatment-and-prophylactic measures, existing diagnostic methods are already insufficient, there is an urgent need for additional research methods. From these positions, it seems promising to study diagnostic and therapeutic measures aimed at improving the quality indicators of orthodontic care for children. The development of the closest possible approach to the diagnosis and treatment of caries during orthodontic treatment in the early stages will help to obtain a stable aesthetic outcome in the treatment of orthodontic patients, and to avoid relapses. In modem orthodontic dentistry acute problem of prevention of dental caries and periodontal diseases, especially in children and adolescents who have not yet completed the process of mineralization of hard tissues: soon after teething create a situation of increased risk of tooth decay. The purpose of this paper is to analyze complex information about methods of prevention of dental caries in patients with removable and non-removable orthodontic appliances

The problem of cerebrovascular diseases and stroke is significant not only for clinical neurology, but also for society as a whole. Stroke is the second most common cause of death in many developed countries. In Russia, more than 450 thousand cases of this disease are registered per year, and in the Republic of Uzbekistan there are more than ten thousand cases, the mortality rate in the acute period of stroke in Russia reaches 35%, increasing by another 12-15% by the end of the first year after the stroke. Stroke ranks first among the causes of persistent disability, which necessitates timely drug therapy not only in the acute period of the disease, but also throughout the recovery phase.

The immune status has been studied at 25 HIV-infected of children with ARS. The control group of comparison consisted from 14 practically healthy faces. At a HIV-infected of patients with ARS has revealed deep infringements of the immune status, especially from the T-link of immunity and its subpopulations, and also frustration humoral an immunity link, suppression of proinflammatory cytokine IL-10 and increase proinflammatory IFN-γ. Under the influence of the spent treatment have not revealed certain changes from the immune status at patients. It is possible to ascertain only positive changes of maintenance IL-10 and parallel decrease IFN-γ in dynamics of treatment.

Artistic and poetic changes in the novels of the independence period, theoretical views on the expression of polyphonic images in Uzbek novels. The world of images in the novel The Fortified Moon by the talented novelist Shoyim Botayev analyzes the uniqueness of the interpretations in the polyphonic image, which stems from the novel thinking. The process of characterization of images and the artistic function of conflict in the work are discussed.

This article explains the state of the ENT organs in twins and the rhythmic manifestations of life changes in them. Based on this article, it will be possible to find out what diseases of the throat, nose and the auditory system are susceptible to children born on the basis of multiple pregnancies. To assess the role of hereditary and environmental factors and the development of diseases, pathological changes in the functional and anatomical aspects of the ENT organs in Gemini are still observed. In addition, in Gemini, the pathology of anatomical and physiological defects of the ENT organs is more common in twin children in the perinatal period, in comparison with children born alone. Changes associated with the work of the respiratory organs and the same systems are becoming more and more noticeable, including with the formation of ENT organs and, in particular, a sound analyzer, a deviation of the nasal barrier, nasal congestion and, accordingly, an increase in defects that further will exert their influence on other organs of the body.

Dental diseases in children, such as carious lesions of deciduous teeth, traumatic injuries of the oral cavity occupy one of the first places among chronic diseases. A feature of the oral cavity in children is that with any traumatic injury, the mucous mem-brane instantly becomes infected. Separate use of techniques such as infrared radiation - a spectrum of electromagnetic waves, laser treatment, ultraviolet rays for traumatic injuries of the oral cavity did not always give the expected effect. The study of the effect of the apparatus of magnetic-infrared-laser therapy (MIL-T) “Sogdiana” in children with trau-matic injuries of the oral cavity, was more effective than traditional therapy.

Among dental diseases, periodontal diseases dominate in their intensity, prevalence and devastating consequences for the dentition of the person. In this regard, the search for effective methods for the diagnosis, treatment and prevention of inflammatory periodontal diseases remains urgent. Recent studies have allowed to expand and complement the modern view in the regulation of many physiological processes of the body. Periodontal diseases are no exception. It is well known that in the complex treatment of periodontal diseases, dentists use a wide arsenal of medications that affect both the microflora of periodontal pockets and various mechanisms of the pathogenesis of the inflammatory process. However, modern methods and tools do not fully justify their clinical effectiveness. In this regard, an integrated approach to the treatment of gingivitis is gaining increasing recognition in dental practice.
Aim:To study the causes of hypertrophic gingivitis in adolescence, find optimal treatment options, introduce new methods in the treatment algorithm.
Material and research methods.
The study used material (oral fluid, gingival blood) obtained from 50 patients aged 12-18 years with a diagnosis of moderate hypertrophic gingivitis and 20 healthy individuals.
Depending on the treatment and preventive measures taken, all patients were divided into 2 groups of 25 people each. In the 1st control group for treatment, traditional antiseptic treatment of the oral cavity was used using a 0.05% solution of chlorhexidinebigluconate and periodontal pockets were injected with a metrogel dent gel under a bandage in the amount of 10 g for 5-7 days. In the 2nd group (n = 25), patients underwent anti-microbial, topically anti-inflammatory and decongestant therapy. Traumeel C 301.5 mg in the form of a paste was injected into the interdental space under a dressing in the amount of 10 g for 5-7 days. The 2nd group was taken as the main one.
The clinical condition of periodontal tissues was evaluated using the following indices: hygienic (Green-Wermillion), PI (Russel). The state of immune resistance of the oral cavity was evaluated using cytological methods (determination of the content of cellular elements in the liquid of the periodontal pocket); assessment of the absorption activity of neutrophilic leukocytes by calculating the phagocytic number during the induction of phagocytosis by latex particles, as well as the test of spontaneous reduction of nitro blue tetrazolium (HCT test).
Statistical data processing was performed on a PVEM using MS Excel 10.0 tools.
Results.When examining patients, hyperemia of the gingival mucosa, swelling, loose consistency, bleeding, a small amount of supra and subgingival tartar, profuse soft plaque, false pockets up to 5 mm with serous exudate, papillae enlarged and deformed, hypertrophy up to 1/2 were determined the length of the crown of the teeth, the average value of the clinical indices was IG - 2.58 ± 0.5 and PI - 5.5 ± 0.4. After completion of the 
course of therapy, improvement was noted in patients of all groups: tightening of the gingival margin, decreased bleeding, disappearance of false pockets. The positive dynamics of changes in the index indicators of the periodontal condition was noted. The highest results were achieved in the 2nd group, where the value of the PI indicator from 2.58 ± 0.5 points to 0.14 ± 0.1, PI from 5.5 ± 0.4 to 2.56 ± 0.8 (p <0.05).
Conclusion. Thus, the effectiveness of the local use of the drug "Traumeel C" is confirmed by the results of clinical and laboratory studies.