Online ISSN: 2515-8260

Issue 5,

Issue 5


Evaluating the Psychological Distress of the Coronavirus Disease 2019 Pandemic in Egypt

Radwa Abdullah El- Abasiri; Roy RilleraMarzo; Heba Abdelaziz; SherifBoraii .; Hamed Abdelaziz

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 1-12

Background: The increasing numbers of infected cases with Coronavirus disease (COVID-19) overwhelmed the population all over the world. The advice with regard to social distancing and staying at home were recommended in the community which have led to the spread of psychological distress.
Objective: To assess the psychological status of the general population in Egypt during the coronavirus disease (COVID-19).
Methods: The authors conducted a cross-sectional, observational survey before the peak of the pandemic in Egypt through an online questionnaire. It was shared through e-mails and different social media platforms. The COVID-19 Peritraumatic Distress Index (CPDI) questionnaire adapted by the Shanghai Mental Health Centre was used to inquire about the incidence of anxiety, depression, specific phobias, cognitive changes, avoidance, compulsive behaviors, physical warning signs, and loss of social interaction in the aforementioned period. Logistic regression was used to analyze factors affecting CPDI score to evaluate the relationship between CPDI category, socioeconomic, and demographic characteristics.
Findings: Overall, 523 eligible participants were enrolled (including 266 health care workers (HCW) and 257 non-HCW). It was found that 51.9% of HCWs experienced mild to moderate distress, while 15% experienced severe distress. Additionally, non-HCWs’ results showed that 39.7% of them experienced mild to moderate distress; 21.8% experienced severe distress (OR: 0.717; 95% CI: 0.493–1.043). Moreover, the percentage of females with severe distress (21.7%) was two times higher than that of males (10.7%) (OR: 0.412; 95%CI: 0.278–0.612).
Conclusion: Public health emergencies such as COVID-19 increase the psychological distress liability of the general Egyptian population. Promoting mental health well-being, as well as behaviorally public psychological engagement during outbreaks, is required to support people who are distressed and to ameliorate their mental health.

EFFICACY OF ULTRASOUND MASSAGE THERAPY IN MYOFASCIAL PAIN –A RANDOMIZED SINGLE-BLIND CLINICAL STUDY

Dr. Richa Jain; Dr. Amit Mhapuskar; Dr. Darshan R.Prasad Hiremutt; Dr. Kedarnath Kalyanpur; Dr Harshit Badani; Dr Rahul Hari Koppala

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 13-25

Aim:To compare the efficacy of conventional therapy over combination of Therapeutic Ultrasound & Conventional therapy in management of Myofascial pain patients.
Keywords: Myofascial Pain Dysfunction Syndrome (MPDS), Therapeutic Ultrasound, Temporomandibular disorders, Orofacial Pain, Combination Therapy
Materials and Methods:
The present randomized comparative study was conducted on 20 patients who came to the Out Patient Department of our institute with a complaint of Myofascial pain.All the patients were evaluated for pain over TMJ area and muscles of mastication on a visual analog scale (VAS), maximum inter incisal distance was measured by Vernier caliper. Patients were randomly assigned into two groups each comprising of 10 patients. Group I
patients received conventional therapy while Group II patients received combination of Conventional therapy and Therapeutic Ultrasound. Descriptive Analysis of the dataset was carried out to obtain data estimates and all the variables i.e. Mouth opening (MO), Pain recorded as per visual analogue scale on TMJ, Masseter (M) and lateral pterygoid (LP) muscles in nature except the gender of the patient for which frequencies were observed. The means of the differences between the values of the two groups were compared using Wilcoxon Rank Sum Test/ Mann Whitney U-test.
Results – A significant pain reduction was found in the patients who were given Ultrasound massage therapy (p – 0.003). There was a decrease in pain over TMJ area, tenderness over Masseter and lateral pterygoid and mouth opening was improved which was statistically significant. This therapy appears to be effective in pain reduction in Myofascial Pain Dysfunction Syndrome.
Conclusion–US massage therapy appears to be useful in relieving pain and improves subsequent mouth opening, and hence can be considered as a valuable aid in managing Myofascial pain. Thus, US massage therapy serves as a potent and independent therapeutic modality in Myofascial Pain Dysfunction Syndrome.

ESTIMATION OF EFFECTS OF VARIOUS ROTARY CUTTING BURS IN THE SHEAR BOND STRENGTH OF THREE DISSIMILAR FLOWABLE COMPOSITES USED IN VARIOUS PEDODONTIC PROCEDURES- A SCANNING ELECTRON MICROSCOPIC CUM IN VITRO STUDY

Sunil Pandey; Prince Kumar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 26-34

Aim: There have been tremendous modifications in the composition as well as in properties of composite resins in the recent past. This study was performed to assess the effects of usage of different rotary cutting burs in the shear bond strength of three different flowable composites on tooth surface used in various pedodontic procedures. Surface changes were also evaluated using Scanning Electron Microscopic (SEM). Materials & Methods: This study was attempted on sixty freshly extracted permanent mandibular molars. Initially teeth were sectioned at coronal one third and polished with abrasive paper made up of silicon carbide. The samples were separated into 2 groups of 30 teeth each. In group I, teeth were prepared using fissure carbide bur and in group II with coarse taper round end diamond bur. Teeth after preparation were again segregated into 3 groups. In Group A, prepared teeth were applied with Vertise Flow which is a self adhering type of flowable composite resin. In group B, all prepared teeth were applied with Dyad flow (Kerr) SAFC. In Group C samples, Tetric N Bond which is a self‑etch adhesive was applied on the dentin surface. Teeth were then subjected to universal testing machine for evaluation of shear bond strength. Surface texture characteristics and changes were further explored by Scanning Electron Microscopy. Results: Data thus obtained were compiled for statistical analysis by latest SPSS software package. Shear bond strength (SBS) in group C was 22.4 MPa, in group B was 15.1 MPA and in group A was 12.8 MPa in group I. However when checked in group II, group C had SBS of 18.2 MPa, group B had 12.6 MPa and group A had 11.2 MPa. Therefore, author noticed non- significant difference (P = 0.71) in SBS values of flowable composite resin (self-adhering)Group A) for surfaces prepared with carbide (Group I) and diamond (Group II) burs. Conclusion: The shear bond strength (SBS) of Tetric-N Flow was reported to be higher when compared to other tested materials. Dentinal surface those prepared with carbide bur showed higher shear bond strength for Tetric N Flow and Dyad-flow. Clinical Significance: In the present in vitro study, the overall breaking shear bond strength (SBS) was reported higher in samples those prepared with carbide burs. Also, Tetric N Flow expressed highest values among the studied composites. These findings are very crucial and have a clinical applicability in selection of type of burs for critical and prone pedodontic circumstances.

Impact on Routine Immunization Services During the Lockdown Period in India: Implications and Future Recommendations

Nishantadeb Ghatak; Roy Rillera Marzo; Sheikh Mohd Saleem; Neha Sharma; Amarjeet Singh; Sudip Bhattacharya

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 35-40

World Health Organisation (WHO) declared the ongoing COVID-19 as a global pandemic on March 11, 2020.For this advancement, countries all over the world has begun to implement lockdown as one of the strategies to tackle the spread of SARS-CoV-2 virus. Like other countries, the lockdown in India also poses serious problems to the health industry and to many other sectors. One of the severely affected and ignored programs, the Universal Immunization Programme (UIP)which approximately addresses 27 million new-borns seeking immunization per year, is also suspended. In this scenario, outbreaks of vaccine-preventable diseases could be catastrophic for communities and health systems which are battling the impacts of COVID-19. At present, there exists no definite medicine and vaccine for COVID-19. The immunity of an individual plays a crucial role in the prevention of disease as well as severity. The interruption of vaccination program can give rise to a resurgence of measles cases. This resurgence can lead to profound immunosuppressants which can cause an increased incidence of COVID-19 with a rise in the number of severe cases which eventually leads to increased mortality rate. Moreover, the suppression of immune function can lead to increased incidence of other infections which may have a huge burden to the healthcare system where services have already been compromised due to low resources. Lessons should be learned from Europe and Africa. Initiatives should be taken to restore the routine immunization program immediately with all precautionary measures as per WHO guidelines.

Current Mathematical Models and Numerical Simulation of SIR Model for Coronavirus Disease - 2019 (COVID-19)

M. Suba; R. Shanmugapriya; S. Balamuralitharan; G. Arul Joseph

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 41-54

This paper deals with seven mathematical models within the current COVID-19
pandemic situations. We developed a number of mathematical models which are
compartment solutions of nonlinear differential equations. These models are useful for
research scholars, faculty members and academicians in the area of mathematical biology.
Also, we study these models and parameter estimation from real-world problem (data of
COVID-19 in World Health Organization (WHO)). The researchers discussed to analyze
the possible solutions of each model in the general discussion section. The researchers
recommended that at the end of the year 2020, there will be a reduction on the spread and
an increased recovery rate of COVID-19. These situations are fully changed and return to
the normal life very soon. In this paper to the researchers discuss the simple SIR model
compared to real-life data for COVID-19 pandemic in Tamilnadu by district wise. This
model helps to predict the future calculations of Susceptible, Infections, and Removed
people from the total population and reproduction number R0 . The researchers conclude
that the infection rate is increased for the next two months (September and October, 2020),
and death rate percentage is also possible to decrease from the number of total
populations. Also the researchers recommend the continuous lockdown for these two
months and for all people to follow the instruction given by the Tamilnadu Government.

DNA based CGB methylation in breast cancer a case control study

Dr. Anjana Vasudevan; Dr. Vasugi. G. A.; Dr. R. Ponniah Iyyappan; Dr. Harpreet Kaur; Dr. Balaji Singh; Dr. Guru Prasad; Dr. C. S. Subramanium; Dr. C. Kaliyappa

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 55-61

Breast carcinoma is the most commonly diagnosed cancer and the leading cause of cancer death. Breast cancer also produces and is influenced by ectopic hormones. Beta Human Chorionic Gonadotropin (hCG) is one such hormone and is encoded by chorionic gonadotropin beta (CGB) genes. The aim of this study was to determine the CGB gene methylation in breast cancer tissues and compare them with normal tissues.
Materials and methods: After approval from Institutional Ethical Committee (IEC), consent from patients were obtained. Normal and tumour tissues from breast cancer patients were taken. DNA was isolated from normal and tumour tissues. Post bisulfate conversion samples were processed for qPCR using methylation specific primers for the set of selected CGB genes and SYBR green.
Results: 1-2M was found to be significantly higher among the normal tissues (50.22). 3-9M was found to be 65.93 in tumour tissues and 5.05 in normal tissues and this was significant.
Conclusion: 3-9 M is significantly higher in tumour tissues compared to normal tissues and 1-2 M is significantly higher in normal tissues. This suggests that there are 2 different types of beta hCG secreted by two different types of genes and this can be used for further analysis as a part of future projects. This may help in formulating a new treatment process and may also be used as a tumour marker in high risk patients

A Novel Approach Of Techno-Economical Power Generation By Savonius Type Vertical Axis Wind Generator

Damala Rajesh Babu

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 62-72

As power generation demand is being increased in renewable energy sector, power generation from wind energy plays important role in present growing scenario. The design of wind generator is a important parameter to extract the power from wind. In this paper a new approach is explained how maximum power is being obtained. The strong magnets Neodymium magnets N52 were used in this design of wind generator. The vertical type which is most common using now is used in this design. The voltage generated by each coil is presented in this paper. It proves that using two magnetic stator and one coil rotor improves power generation. The modified Savonius vertical axis wind turbine performance can be identified in this paper. The construction design and components details are discussed here.

Multi-Attribute Performance Analysis Model For Collaborative Cloud Environment Using TCP

VelMurugeshKumar. N; R. Nedunchelian

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 73-90

The problem of collaborative computing in the cloud environment has been well studied. Several approaches available to handle the issue of collaborative computing and still suffer to achieve higher performance in different QoS parameters. The performance of various simulation models has been analyzed for different parameters in this paper. To improve performance an efficient multi-attribute performance analysis model has been presented. The method first presents a collaborative content sharing strategy (CCSS) which maintains a dual copy of any resource in the cloud which has been accessed by different users. The method enforces an attribute-based update restriction (ABUR) algorithm which uses different keys to restrict malicious updating from different users. The public auditing has been enforced with ABUR and CCSS algorithms. The multi-attribute performance analysis model estimates various QoS parameters like throughput, completion, and public auditing on various simulation models of the cloud environment. A testbed is generated to simulate the performance of different cloud computing tools in a collaborative environment. The performance of simulation models has been measured and compared with the results of other models in detail

Dynamic Stability Enhancement Of Ieee 30 Bus System With Gapod And Gadcvr Controllers Based Upfc

Amrutha P; Srinivasa RaoC; Vijaya Kumar M

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 91-100

This paper proposes a combination of Genetic Algorithm based Power Oscillation Damping (GAPOD) and DC Voltage Regulator (DCVR) controllers are proposed for Unified Power Flow Controller (UPFC) for the enhancement of dynamic stability of IEEE 30 bus system. The difference between mechanical power and electrical power is the input to the GAPOD, and the output of GAPOD is connected to UPFC one of the input and the input of GADCVR is deviations of capacitor voltage and this output connected to another input of UPFC. GA tunes the parameters of POD and DCVR by minimizing the error; this error is the difference between mechanical and electrical power. The proposed method is applied to IEEE 30 bus system in MATLAB/Simulink environment, and results compared with Genetic Algorithm based Multi Stage Fuzzy DC Voltage Regulator (GAMSFDCVR) and conventional controllers. The results demonstrated that the proposed controller is effectively damping the oscillations.

Wet And Dry Dressing On Post Herniatomic Patients For Wound Recovery In Pirngadi Hospital.

Megawati .; Agussalim .

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 101-107

Wet and dry dressing is one of the factors that have a major influence in the
process of wound recovery. It is a way to protect from widespread infection in postoperative
of herniatomy. Purpose of this study was to identify the difference in the
provision of wet dressing in post-operative of herniatomy patients. This type of research is
cross sectional analytical design. Sampling method was accidental sampling. The samples
of this study were 30 people. Result of this study shown that using wet dressing 16 people
(53.3%) and those not using wet dressing 14 people (46.7%).Another side who were fast
wound recovery 16 people (53.3%) and the slow healing of the wound 14 people (46, 7%)
used dry dressing 18 people (60.0%) and who did not use dry dressing 12 people (40.0%),
there were fast wound healing 18 people (60.0%). The Odd Ratio results obtained = 0.067
means that respondents who do wet dressing are likely to have a risk of 0.06 times greater
risk of infection. It can be concluded that there are differences in the provision of wet and
dry dressing in postoperative patients with herniatomy. Based on the study, it can be
concluded that there were differences in the provision of wet and dry dressing in postoperative
herniatomy patients in Pirngadi Hospital Medan

Association Between Personality Traits, Dental Anxiety And Socioeconomic Profile With The Dental Myths Among Adults In Chennai City, India

Divya Raghunathan; Preetha Elizabeth Chaly; Mohammed Junaid; Shyam Sivaswamy

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 108-118

Purpose: The objective of the present study was to evaluate the association between personality traits, dental anxiety and socioeconomic profile with the dental myths among adults in Chennai City, India.
Methods: A pilot study was conducted among 90 adults aged 18 years and above by multistage random sampling methodology across the socioeconomic groups. The final sample size was found to be 162. A validated and a reliable, bilingual, self-administered questionnaire consisting of four sections namely 1. The demographic details, 2. Personality traits, 3. Modified Dental Anxiety and 4. A 26-item dental myth questionnaire. The collected data was analysed using SPSS version 20.0 and Chi -square test, One way ANOVA and correlations were done and a p-value <0.05 was considered as statistically significant.
Results: Dental myth scores was found to be more in the middle social class, followed by the lower and higher social class and this difference was not statistically significant (p=0.21). The personality traits and dental anxiety were found to be weakly correlated with dental myth scores.
Conclusion: The startling results of the study have shown no relationship between socioeconomic status, dental anxiety, personality traits with the occurrence of dental myths.

Estimation Of Salivary Alkaline Phosphatase Levels In Smokers And Tobacco Chewers Associated With Diabetes

Sushmitha M; Preethi. M; B. Sivapathasundaram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 119-128

Background:- Alkaline phosphatase is the group of hydrolytic enzymes that are involved in the cellular metabolism. Alkaline phosphatase in saliva is used as an indicator of gingival inflammation, bone metabolism and other oral lesions like premalignancies and oral cancer.
Aim and objective: To estimate the levels of Salivary Alkaline Phosphatase (S-ALP) in smokers and tobacco chewers associated with diabetes and diabetics without any habits. Materials and Methods: The study includes 30 cases and 10 control. 30 cases divided in group A, B and C and control group D: (1) Group A - 10 smokers who are diabetic. (2) Group B - 10 tobacco chewers who are diabetic. (3) Group C - 10 nonsmokers and non-tobacco chewers who are diabetic. (4) Group D - 10 nonsmokers, non-tobacco chewers and nondiabetic as control. Saliva was collected from the subjects of the above mentioned groups and the levels of S-ALP were estimated using a semi auto- analyzer and comparison was made. Results: The result reveals increase in the alkaline phosphatase levels in saliva of smokers and tobacco chewers with diabetes group (Group A, B). Non-smokers and non-tobacco chewers with diabetes group (Group C) had higher level compared to the control group (Group D). Conclusion: Salivary alkaline phosphatase is a clinical biomarker that is used to determine the oral diseases due to adverse habits and diabetes at its early stage.

HYBRID SOLAR AND WIND ENERGY SYSTEMS WITH CONVERTER DESIGN

V. Srikanth Babu; Damala Rajesh Babu

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 129-138

In the context of increasing demand for energy and regarding the availability of conventional energy sources renewable plays a crucial role in nowadays, But we can’t assure continuous supply from these renewable as their performance totally depends on the weather conditions. So, in order to overcome these problems to some extent hybrid systems are used. This work addresses a new concept in a hybrid system i.e., the photovoltaic cells are placed on the wind blades. Thus, this model signifies the reduction in design, optimizes the cost, and to shows the new development in renewable. This paper explains darrieus model of vertical-axis wind turbines (VAWTs) accompanied by polycrystalline solar cells. This system is connected to 555 timer astable mode of operation of the boost converter and a protected model of charge controller for the battery. So, to exploit the energy efficiently by this hybrid model i.e. extract of solar energy from panels and wind energy from darrieus wind turbine at a time helps to meet the concept of uninterrupted supply on besides the discontinuity of nature. A small working model is also developed basing on this concept and it is performance curves of the wind and solar are obtained.

The Use Of Abdominal Aorta Length In The Fetuses’ After 34 Weeks Of Gestation For Calculating Gestation Age Among Primigravida Healthy Women

Dr Najlaa Hanoon; Dr Wisam Akram

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 139-149

Aim of the stud; To verify the correlation between abdominal Aorta Length in the fetus and gestational in weeks between 34- 40 weeks
Type of study; Case Control
Methods; a healthy pregnant women were chosen who’s age between 15-40 years all are primigravida and conceived within 3 months of marriage. They were between 34- 40 weeks in gestation. Their last menstrual period was know and recorded in addition all were scheduled for ultrasound examination for measurement of the abdominal aorta length, femoral length and biparietal diameter.
Result; a highly significant correlation was found between abdominal aorta and biparietal diameter and femoral length . In addition a highly significant correlation was found between gestational age calculated by their LMP and abdominal aorta. In addition a highly significant correlation was found between gestational age and abdominal aorta length. A non linear exponential equation was constructed with lowest mean of sum of squares=1, and coefficient of correlation= 0.97 between abdominal aorta length and gestational age in weeks. From this equation a reference table built which contains value for the abdominal aorta between 34- 40 weeks for 1,2.5,5,10,90,95, and 99 centiles. After the building of this table further 35 women were taken for assessment of this table. Only 2 were miss calculated, the Kappa Cohen coefficient=0.93
Conclusion; a table by which the gestational age can be calculated between 34-40 weeks by measuring the abdominal aorta. However under no circumstances this table may be used apart from assessment applications. Further studies are required to verify its accuracy

Optimization Of SLL Of Rectangular Array Antennas Using Enhanced Firefly Algorithm

Bhagya Sri N.K. Kagitha; Venkateswara Rao Nagalla

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 150-159

Firefly Algorithm is a stochastic and meta heuristic approach inspired from nature having a wide range of applications in solving various optimization problems. Firefly Algorithm (FA) suffers from problem of slow convergence speed. This problem can be solved by using modified Firefly algorithm called as Enhanced Firefly Algorithm. By using this algorithm side lobe level of rectangular antenna array can be reduced considerably without appreciable effect on beam width. SLL is most important array pattern parameter because reduced SLL results in minimizing received noise and interference. Low SLL in the radiation pattern of the rectangular antenna array can be achieved by considering phases and amplitudes of the excitation currents of elements of array as variables to be controlled having fixed spacing between the elements. In this paper SLL of symmetric rectangular array antenna is optimized using Enhanced Firefly algorithm (EFA) and its results are compared to the results obtained with Genetic Algorithm.

Secure Hybrid Watermarking Technique In Medical Imaging

G. Nagaraju; P. Pardhasaradhi; V. S. Ghali; G.R.K Prasad

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 160-176

Medical imaging organizations currently face a significant problem with stealing of medical data. Watermarking is a powerful tool that can be used to authorize the hidden information in cover image. The unique features associated with watermarking are authorization and copyright protection. Because of its unique characteristics, watermarking associated with medical data hiding gives more robustness in medical imaging. In spite of this adding security to watermarking in medical imaging, gives more protection for medical information. This paper explored two main fields that, the encryption of medical images using DNA Encoding and Spatiotemporal Chaos Algorithm and the embedding of medical images in cover image using hybrid transformation of NSCT, RDWT and SVD. The goal of this study was to develop a methodology to improve the robustness, imperceptibility and security for medical information without implementing a physical model, thus saving time, money and reducing the risks associated with hacking partners. For this paper, I used patient health document as one watermark and his medical image as another watermark. The theoretical model has demonstrated that it is possible to use this type of technique and apply it to a complex digital image transmission. The correlation observed before and after encryption and embedding procedures. Experimental results show how robustness and imperceptibility and security of medical images are improved.

Energy Saving And Security In A Building By Landscaping And Electric Devices Controlling By Wi-Fi Module.

Ravi Kumar Jalli; Vijaya Krishna Rayi; NSS Rama Krishna

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 177-184

We live in a time where many technological advancements are at our fingertips, our lives are made easier, which is fortunate considering the fast-paced lives most of us lead. In recent years, great strides have been made in making homes a bit more “tech savvy.” This technology, in short, allows the homeowner to run his or her home while away through remote, often on a Smartphone or iPad. In our project we presented a prototype implementation of home automation system that uses wifi technology as a network infrastructure connecting its parts. Previously Bluetooth module was used for this purpose which has reduced control since it covers small distance, high power consumption due to Bluetooth connectivity. We are using ESP8266 wifi module which is a self contained SOC with integrated TCP/IP protocol stack that can give any microcontroller access to your wifi network. For home security we are using PIR motion sensor which are basically made up of pyroelectric sensors which can detect the level of infra-red radiation. It almost always used to detect whether a human has moved in or out of the sensors range. These home automation systems provide increased comfort especially installed in private home. The conclusion of our project is to increase overall energy saving which is main issue today.

New Age Treatment For An Age Old Problem PRP For Post Surgery Non Healing Venous Ulcers

Dr. Nithyaraj Prakasam; Dr. Anjana Vasudevan; Dr. Guru Prasad; Dr. Vivek Bala; Dr. K. Senguttuvan

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 185-192

Introduction: One of the major complications of varicose veins is the non-healing ulcer of the leg. The traditional treatment for this is regular dressing, foot end elevation with appropriate antibiotics and local application of silver-based ointments. The gold standard treatment for these patients is surgery (Trendelenburg surgery with or without venous striping and subfascial perforator ligation and endovenous procedures). Surgeons usually reach a crux when a patient develops persistent ulcers which does not heal even after all these efforts.
Aim: Our objective in this study was to study the effects of Platelet Rich Plasma (PRP) in chronic non-healing post-surgical venous ulcers.
Methodology: This was a case control study with 40 patients conducted over 2019 and 2020, after institutional ethical clearance. All patients were treated with appropriate antibiotics prior to the study and obtained a culture negative status. PRP was separated and injected locally into the borders of the ulcer in cases, while controls were given regular dressings with silver-based ointments.
Results: We found that patients who were given PRP had a significantly faster healing rate and a lower infection rate.
Conclusion: Hence PRP can be safe, effective and reasonably cost effective in treating post-surgical venous ulcers.

Swami Vivekananda‟s Life And Philosophy

Dr. Anusmita Talukdar

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 193-196

Swami Vivekananda was one of the eminent personalities in the history of India. His work is always remembered as the big contribution to the history of India. He was an Indian Hindu monk who spent his whole life spreading the faiths and beliefs of Hinduism all around the world as well as in India. To be religious for him means leading life in such a way that we manifest our higher nature, truth, goodness and beauty, in our thoughts, words and deeds. All impulses, thoughts and actions which lead one towards this goal are naturally ennobling and harmonizing, and are ethical and moral in the truest sense. He says, we need technical education and all else which may develop industries, so that men, instead of seeking for service, may earn enough to provide for them-selves, and save something against a rainy day. He feels it necessary that India should take from the Western nations all that are good in their civilization. He says for the development of a balanced nation, we have to combine the dynamism and scientific attitude of the West with the spirituality of our country. The entire educational program should be so planned that it equips the youth to contribute to the material progress of the country as well as to maintaining the supreme worth of India’s spiritual heritage.

Impact Of Integrating Biogas And Canal Based Small Hydropower Plants In A Hybrid Power System

R Vijaya Krishna; T S Kishore

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 197-205

In evolving countries like India, there is a swift growth in load and energy demand due to heavy industrial development, urbanization and economy rise. Most of this demand is met through power generation from conventional sources which have adverse environmental impact. Renewable energy resources provide a good alternative but lack of continuous generation, high initial cost, complex control, conversion between AC and DC generation, grid integration etc. are some of the drawbacks associated with renewable energy sources. To overcome these disadvantages and to efficiently utilize the available energy resources, a hybrid power system combining the advantages of individual power sources, can be seen as a preferred option to generate and deliver power. In this paper, an attempt has been made to perform techno-economic analysis of a hybrid power system existing in an educational facility with conventional grid power supply, diesel generator and photovoltaic generation and the results are summarized. An augmentation for the existing system has been proposed with biogas and small hydropower generation systems as these resources are available within the accessible limits of the study area.

Vascular Brain Malformations In Combination With Extracranial Brachiocephalic Artery Lesions

Aleksey Khripun; Aleksandr Pryamikov; Aleksey Mironkov; Sarkis Asratyan; Viktor Suryakhin; Ruslan Loluev; Lyubov Gulina

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 206-213

One of the unresolved problems in vascular surgery and neurosurgery is the
internal carotid artery ex tra and intracranial segments combined lesion, namely the
combination of the arterial aneurysm or vascular brain malformation with extracranial
brachiocephalic arteries lesions. Currently, there are no clear tactical approaches and
recommendations for the brachiocephalic arteries' comorbid pathology treatment. This
article show s the treatment experience of 55 patients with combined lesions of the internal
carotid artery intra and extracranial pool: a combination of the intracranial aneurysm or
vascular br ain malformation with brachiocephalic arteries stenotic lesions or
asymptomatic internal carotid artery pathological deformation at the cervical level.
Clinical cases were accumulated over 6 years (from 2013 to 2019). The incidence of
comorbid pathology wa s 3.5%. The bigger part of brain vascular malformations (53 of 55
patients or 96%) were asymptomatic. The majority of patients with comorbidity were
women 69% or 38 patients )). Surgical activity among the target group of patients was 40%,
22 o f 55 patients were operated on. Repeated ischemic stroke after asymptomatic internal
carotid artery stenting was beared by one patient (4.5%) in the early postoperative period.
Most aneurysms in the first group were localized in the anterior sections of the W illis circ le
(81% versus 11%, p <0.001), saccular aneurysms prevailed (41 patients or 95%). There is an
existing necessity of accumulation brachiocephalic vascular pool comorbid pathology
surgical treatment experience and major studies conduction that should help in the
development of therapeutic algorithms and optimization of surgical tactics for the
brachiocephalic pool combined vascular pathology.

Innovative Methods Of Miscellaneous Skin Inclusions Removal And Post-Inflammatory Hyperpigmentation Correction

Anastasiya V. FridmanSorokina

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 214-221

Scarless tattoo extraction remains as a major problem in a cosmetology field nowadays. At the moment laser removing method is a basic procedure for tattoo removal. However, this technology is painful and leads to significant trauma of the skin cover. Thise article presents a new combination of laser and chemical technique for skin inclusions removal. The group of techniques belongs to the chemical industry and represents a lightning and neutralizing composition and a method for removing a dye introduced under the skin. The skin area with dye is exposed to a laser effect. After laser exposure an oxidizing composition of 2-3 mm thickness is applied. Oxidizing composition: carboxylic acids, fermented celandine oil extracts and propylene-glycol celandine extracts. The main novelty of the method is presented by several chain processes: in applying of the oxidizing composition on the skin surface after laser radiation, a significant role is played by physicochemical characteristics changes of the skin. Without the skin surface damaging, the percentage of chemical reactions dissociations aimed at removing the pigment is raising which shows better efficiency comparing with classical laser method of dye particles removing.

Herpes Virus Hepatitis In Children

Uchaikin VF; Malinovskaya VV; Abe K; Shamsheva OV; Smirnov VV; Polesko IV

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 222-232

Investigating the causation and course of the herpesvirus hepatitis in groups of children and the results of treatment of different types. 173 children with herpesvirus hepatitis were examined. The causation of the disease was verified in all patients with the detection of CMV, EBV, HHV-6 DNA in blood, urine, saliva, and hepatocytes, and of CMV LA, EBNA-2 and EBV LMP1 in hepatocytes of the patients after needle biopsy of the liver. Clinical implications and laboratory findings in acute and chronic herpesvirus hepatitis in children showed no differences in virus hepatitis as a whole. 113 children receiving Viferon® for the treatment of the chronic herpes virus hepatitis were monitored. The Interferon dose of all children was 5 mln/m2 three times a week. In the course of the treatment, the primary biochemical remission was achieved in 15 (13.3%) children, the primary virological: in 8 (7.1%) children, the stable biochemical: in 7 (6.2%) children, the stable virological: in 5 (4.4%), the stable complete: in 3 (2.6%) children, the long-lasting biochemical: in 10 (8,8%) children, the long-lasting virological: in 4 (3.5%) children, the long-lasting complete remission: in 26 (23.1%) children with chronic herpes virus hepatitis. The disease recurrence was found in 7 (6.2%) patients; there were no remission in 28 (24.8%) children. 1/3 of the patients the decrease was recovered with complete recovery of the functional status of the liver within 1-3 months. The result of the symptomatic herpes virus hepatitis the disease of 64.9% of the patients had chronic progression

Results Of Experimental Program For Studying The Coрing Behavior Peculiarities In Higher Education Students

Tatyana A. Serebryakova; Irina A. Koneva; Olga V. Suvorova; Lidia E. Semenova; Natalya V. Fomina; Irina S. Ipatova; Natalia N. Sheshukova

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 233-243

The article reflects the results of an experimental study of the specifics of coping behavior of university students. Considering coping behavior as a special purposeful socially-oriented behavior of a person that ensures his productivity, health and, both psychological and social, well-being, we believe that the formation of the experience of coping behavior is a prolonged process and is carried out throughout a person's life. We determined the study of the specifics of coping behavior among students of a higher educational institution as the target guidelines of our research. Relying on theoretical and methodological provisions in the field of personality psychology, psychology of coping behavior, as well as the theory of stress, we have designed a diagnostic program that included the method of scientific observation, as well as a system of test methods. Our pilot study showed that the complex application of the diagnostic program developed by us makes it possible not only to study the specifics of coping behavior of students within the framework of their educational activities, but also to determine the type of behavioral activity of respondents, the characteristics of their behavior in emotionally stressful situations, and also to determine the main reasons stimulating the onset of stress.

Modeling And Simulation Of A Three Phase Grid Connected Photovoltaic System

M. Vinay Kumar; U. Salma

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 5, Pages 244-261

The need for electrical energy is increasing day by day and the required surplus electrical energy is supplied by renewable energy sources (RES). The usage of RES is a solution to save the fossil fuel reserves for the future generations to come and it also protects the environment. Solar energy as RES has number of advantages like freely available, pollution free, etc., Solar energy is converted to electrical energy using solar photovoltaic (PV) system, it has number of advantages and few challenges too. The generated voltage depends upon solar irradiation and operating temperature. Number of PV systems connected to the grid is ever increasing and this is leading to number of challenges like voltage quality, power quality, islanding etc., and these have to be increased. Solar PV system is used as distributed generator (DG). These DG’s help in supplying the additional electric power demand, improve the power quality, reduce the distribution losses, etc., This paper presents mathematical modeling of PV cell, DC/DC converter, inverter and maximum power point (MPP) controller. The discussed model is designed with Simulink block libraries and done in Matlab/Simulink software. Simulations are done and the results are deliberated and discussed.