Online ISSN: 2515-8260

Keywords : Antihypertensive drugs


INFLUENCE OF SERUM MAGNESIUM LEVELS ON PRIMARY HYPERTENSIVE CASES AND ITS ASSOCIATION WITH CARDIOVASCULAR CHANGES AND RETINOPATHY

Ravi N Sangapur Anusha N Sangapur

European Journal of Molecular & Clinical Medicine, 2021, Volume 8, Issue 4, Pages 1514-1518

 
Background: Hypertension is a growing concern in the Indian population with urbanization and developments in work culture and treatment methods.
Aim and objective: To evaluate the influence of serum magnesium levels in gradations of primary hypertension and evaluate its impact on co-morbid conditions.
Methods: Hypertensive patients were screened and included in the study by categorizing them in to grade I and II based on blood pressure levels. Socio-demographic, physical and systemic examination details were recorded with pre-designed questionnaire; electrolyte levels, fasting blood sugar, status of retina and heart were assessed and analyzed using t-test and logistic regression.
Results:Total 100 patients in the study, mean age was 59.3±14.79 years; male predominance (61%); normal retina (83%) and presence of pre-diabetic conditions (67%) was observed, with normal serum magnesium levels in majority (76%). Serum magnesium levels were significantly associated with grade I (P = 0.0173) patients; influencing systolic and diastolic blood pressure values (r = -0.3552, P = 0.003; r = -0.2160, P = 0.0309, respectively).
Conclusion:The optimal values can be further established by evaluation of large sample size, quality of life during treatment, and influence of co-morbidities/complications of hypertension, among others.
 

CLINICAL PHARMACY ACTIVITIES IMPACTING CONTEMPORARY PRESCRIPTION PATTERN OF ANTIHYPERTENSIVE DRUGS AND ITS COMPELLING INDICATIONSIN A TERTIARY CARE TEACHING HOSPITAL

Naga Latha Dhulipalla, Shashi Kiran Mishra, Varun Dasari, Veena Gadicherla, Perli Kranti Kumar

European Journal of Molecular & Clinical Medicine, 2018, Volume 5, Issue 1, Pages 476-491

Hypertension has been recognized as a common cardiovascular disease & a major risk factor
for congestive heart failure, ischemic heart disease, chronic renal failure & stroke. The aim of
the study is to observe the impact of clinical pharmacy activities on contemporary prescription
pattern of antihypertensive drugs and its compelling indications in atertiary care teaching
hospital.This prospective, study was conductedby reviewing and collecting the data of patients
who were diagnosed with Hypertension and admitted in the hospital. Patient demographic
details such as name, age, sex was collected.In present study we found 387 drug drug
interactions in prescriptions of 450 hypertension patients. However there is a need for improve
patient education on adherence to therapy and greater attention by clinicians to issues of life
style modifications, so as to improve BP control rate in this hospital.