Acute Decompensated Heart Failure (ADHF) is a very severe condition that requires proper and timely intervention to prevent the deterioration of the patient’s status. The purpose of this paper is to review the demographic information as well as the outcomes of the patients in the general medicine and cardiology departments of University Hospital. The study enrolled 1,200 patients with ADHF; 800 of them were in general medicine units and 400 in cardiology units. The study also sought to establish the participant’s age, gender, other diseases, initial symptoms of the disease, and the kind of therapy. The findings pointed out that patients in cardiology units were younger, had higher B-type Natriuretic Peptide(BNP) levels, and received more inotropes and mechanical support. The in-hospital mortality was lower in cardiology units (8% vs. 12%) but the LOS was higher (8. 5 vs. 7. 0 days). The 30-day readmission rates were also comparable with no significant difference between the two groups. These findings suggest that the specialized care in cardiology units is beneficial and point out the directions of the possible improvement of the management of ADHF in general medicine wards.