Background: Breast cancer is the most common female cancer worldwide representing nearly a quarter (25%) of all cancers. Diagnosis of breast cancer is carried out by three medical members, the surgeon, who covers breast examination, the radiologist for mammography and ultrasound, and the pathologist for fine-needle aspiration cytology (FNAC) and core needle biopsy (CNB). Aim of present study is to assess the accuracy of ultrasound guided core needle biopsy in various breast lesions