This paper will only consider PNDs as the quantitative epidemiological study is accompanied by a qualitative study that includes interviews with families and healthcare providers. The findings derived from 300 children with PNDs, 300 parents/caregivers, and 100 HCPs increased knowledge of the frequency and characteristics of ASD, ADHD, LD, and ID. Quantitative research shows that these disorders are burdensome to the family and the quality of life as many families reported stress, financial consequences, and social isolation. The critical themes are identified by using qualitative thematic analysis: diagnosis at an early age, the idea of working with each child separately, and the importance of assistance. Families describe stress and functioning issues, while healthcare providers report the system and organizational issues and advocate for person-centered and lifelong learning perspectives. The synthesis of the results suggests that early diagnosis, individualized services, and increased awareness and education for professionals to care for children with PNDs should be considered. ABA and CBT are established as evidence-based treatments and are advocated for use in practice.