Background:The primary surgical treatment for breast carcinoma is modified radical mastectomy, particularly in cases of locally advanced breast carcinoma. Seroma development is the most prevalent complication that arises after a modified radical mastectomy. Seroma formation also increases wound infection, the requirement for frequent aspiration, the need for a longer hospital stay, and higher morbidity. Pectoral flap fixation is a beneficial procedure that can be used in conjunction with a modified radical mastectomy. Flap fixation results in the obliteration of superfluous dead space, which reduces the frequency of seroma formation, as well as a decrease in the volume of drain fluid, which results in early drain removal, lowering morbidity and encouraging early mobilization. After meeting the inclusion and exclusion criteria, the participants were submitted to flap fixation in this study. The postoperative incidence of seroma, the day of drain removal, and the volume and kind of drain were all evaluated on a regular basis. Patients were checked on a regular basis for SSI and flap fixation problems such as flap necrosis. Thus, the goal is to investigate the impact of flap fixation in reducing seroma formation and drain fluid volume, resulting in early postoperative recovery.