Online ISSN: 2515-8260

CORRELATION OF HBA1C WITH SERUM LIPID PROFILE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS

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Dr. Srikanth, Dr. vasanthi, Dr. Rama Chandra reddy

Abstract

Introduction: Patients with type 2 diabetes (T2DM) are more likely to have dyslipidemia, increasing their risk of cardiovascular disease (CVD). This study aims to study the association between hemoglobin A1c (HbA1c) and serum lipid profile in T2DM patients. Materials and Methods: This cross-sectional study was conducted for a period of 3 months. A total of 100 patients with T2DM were included in this study. The whole blood and sera were analyzed for HbA1c, total cholesterol (TC), triglycerides (TGs), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Patients were assigned to two groups depending on their glycated hemoglobin values: Group 1 patients with good glycemic control (HbA1c ≤7%). Group 2 patients with poor glycemic control (HbA1c >7%). The statistical analysis was done by SPSS statistical package version 20.0. Results: 100 type-2 diabetes mellitus patients were included in the study out of which 68 (68%) were males and 32 (32%) were females. Values of TC, TG & LDL-C in Good Glycaemic Control group were significantly lower than Poor Glycaemic Control group. Value of HDL-C in Good Glycaemic Control group was significantly higher than Poor Glycaemic Control group Conclusion: In our study, Hba1c has a substantial correlation with lipid profiles. Type 2 diabetes patients are more prone to dyslipidemia. Apart from being a valid glycemic index, HbA1c can also be used as a predictor of dyslipidemia, hence early diagnosis of dyslipidemia can be utilized as a preventive approach for the development of CVD in patients with T2DM.

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