Background: TUBERCULOSIS (TB) is one of the oldest and deadliest disease in the world and also major health problem, archaeological evidences from ancient civilizations have shown the existence of tuberculosis in the prehistoric era. Even though effective chemotherapy for tuberculosis has been available for decades, TB still remains a public health challenge all over the world. Even though the disease is curable, 2million deaths occurring every year that is some 5000 deaths occurring everyday1.