Online ISSN: 2515-8260
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Clinical Profile of Immune Thrombocytopenic Purpura in Paediatric age Group

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Pusala Venkatanarayana1

Abstract

Background: Platelets play a vital role in hemostasis. Idiopathic / Immune thrombocytopenic purpura (ITP) is a common bleeding disorder in children, where autoantibodies mediated consumption of the platelets, suppression of platelet production by bone marrow megakaryocytes leads to thrombocytopenia and bleeding manifestations. Incidence is 6.4 per 10000 among children and 3.3 per 10000 adults per year.1 There is highest male to female ratio in infancy and it decreases with older age groupchildren. No significant seasonal variation. Vaccination may play an important role in the etiology of ITP in infants. History of a preceding viral infection 1-6 weeks before the onset disease is present in 60% of cases. Bone. narrow was routinely performed but evidences confirmedthat its rarely needed at presentation, must be considered if having severe bleeding or not responding to treatment. Materials &Methods:Details about children with ITP who presented to our hospital between October 2020 and August 2021 were collected using a proforma. The study was designed as a cross-sectional study. To meet the sample size, convenience sampling was used.

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