Background: To study and compare the hypertonic nasal douching with normal saline nasal douching in post operative endoscopic sinus surgery. Materials &Methods: A total of 200 subject were enrolled. The age group was 30 to 60 years who underwent surgery were selected. Post operative evaluation was done. All subjects were given antibiotic-soaked nasal pack for around 48 hrs after surgery. All patients were given the same antibiotic in the post operative period till 10 days and then evaluated on 10th and 20th postoperative day. 200 patients were divided into 2 groups as 100 patients each. Group I patients used hypertonic saline for douching while group II patients used isotonic saline for nasal douching. The appearance of nasal mucosa was listed as either normal andedematous. Crusting was described as nil, mild or severe in nature.