BACKGROUND: OPCABG precludes the use of cardiopulmonary bypass & its complications. Indian surgeonsare practicing OPCABGs (70%-80%) than western counterparts (25%). Guidelines suggest OPCABG in high-risk patients AIM OF THE STUDY: To study the efficacy of OPCABG over conventional CABG exclusively even in mild to moderate risk patients. SETTINGS AND DESIGN: Retrospective observational study METHODS AND MATERIALS: Retrospective analysis of 100 patients who have undergone OPCABG & ONCABG 50 each, at our institute from May 2019 - September 2019. Preoperative variables like age, gender, history of prior MI, diabetes mellitus, hypertension, stroke, smoking, risk assessment using EUROSCORE II. coronary angiographic findings like number of diseased coronaries (DVD/TVD/LM), EF, RWMA, severity of MR, total duration of surgery, number of grafts, LIMA to LAD grafts, perioperative inotrope & blood products used, post operative ICU stay & duration of mechanical ventilation. RESULTS: The study results were (p value <0.0001) for following variables- duration of surgery, duration of ICU stay &mechanical ventilation, number of LIMA – LAD grafts, perioperative use of blood products in OPCABG compared to ONCABG group