The importance of managing and evaluating adverse drug reactions in medical care is for guaranteeing patient safety and achieving the best medical results. ADRs can vary from slight and brief to extreme and life-threatening and can appear in any medical situation. This abstract underline the value of organized procedures for the assessment and managing of ADRs. The assessment of ADRs involves gathering comprehensive patient information, including medical history, medication use, and symptomatology. Recognizing the temporal relationship between drug administration and the onset of adverse events is essential for accurate identification and assessment. Various tools, such as causality assessment algorithms and probability scales, aid in determining the likelihood of the drug's involvement in the adverse event.