The aim of the study was to assess the effectiveness of REBT on the level of depression among depressed patients in selected rehabilitation centres. The final study includes samples of 60 depressed patients. On the Purposive basis the sample are selected. In this study Beck’s Depression Inventory scale was used. The samples received 20 sessions of REBT intervention. Pre-test and post-test was done .In the conclusion the result shows that there was reduction in the level of depression after the intervention of REBT therapy. Material & Method: An experimental study was conducted on 60 depressed patients admitted in selected rehabilitation centres. The samples were selected through non probability purposive sampling techniques. In this study Beck’s Depression Inventory scale was used which consist of 21 multiple choice self- report inventory questionnaire. Result: Out of 60 Samples in Pre test majority 80% samples were in the moderate level ,13.4% in the borderline level and 3.3. in the mild level of depression whereas in the post test majority 80% are in the mild level of depression, 13.4% in moderate and 3.3% in borderline and severe level of depression. Conclusion: REBT therapy was found to be highly effective in decreasing the level of depression among depression patients. This has been proofed statistically as the calculated value is less 0.05 level of significant.