Background-Ayurveda’s main aim is to prevent diseases. F o r a healthy lifestyle, Ayurveda stresses a lot on having sneha (unctuous food), especially Goghruta. Today’s lifestyle is devoid of any discipline leading to many health issues like heart disease, obesity, diabetes, etc. Invariably the common finding in these diseases is elevated lipid profile leading to exclusion of unctuous food from the diet. Still, the count of people suffering from these diseases is increasing day by day. Ayurveda states ghee is an important nutrient for all. It also describes various benefits of consuming ghruta in different prakruti. So, there is a need to understand the relation of prakruti with respect to the metabolism of lipids and to establish the precedence of snigdhatva (unctuousness) in food as stated in Ayurved physiology for achieving longevity and health. The evaluation of efficacy of goghruta on lipid levels in dwandvaj prakruti was the primary objective of the study. The methodology The study has been conducted on individuals with normal lipid profiles for a period of 45 days. The participants were divided into six groups according to Prakruti and were evaluated for all 5 parameters (serum cholesterol, serum triglyceride, serum HDL, serum LDL, serum VLDL) of lipid profile prior to and after Goghruta consumption with a meal for a period of 30 days on a daily basis. Lipid profile was studied on day 15, day 30, and without giving Goghruta at day 45. Observation and result-It have been observed that daily intake of 30 ml of Goghruta increases serum HDL level only in subjects of Vata Kapha Prakruti. Vata Prakruti persons may have the physiology of absorption of good cholesterol into the body due to Ruksha (dry) property. Thus, a relation between Goghruta and healthy cholesterol is established. Goghruta does not increase the levels of serum cholesterol, serum triglyceride,serum LDL,serum VLDL . It isirrespective of Prakruti. The conclusion-The study concluded that Sneha is indeed an important element in the food. Goghruta up to 30ml can be consumed by the persons of all Prakruti on daily basis.