Background:The present study evaluated level of PCT in saliva as well as in PICF in periimplantitis along with healthy subjects. Materials & Methods: 25 patients of peri-implant mucositis (group I), 25 of peri- implantitis (group II) and 25 healthy controls (group III) were assessed for peri-implant plaque index, probing depth, and bleeding on probing at four sites per implant was performed. The measurement of PCT in saliva and peri- implant crevicular fluid was performed. Results: The mean salivary flow rate was 0.61 ml/ minute in group I, 0.64 ml/ minute in group II and 0.63 ml/ minute in group III. The mean salivary procalcitonin level was 3.12 pg/mL in group I, 18.4 pg/mL in group II and 48.5 pg/mL in group III. The mean PICF flow rate was 0.75 μl/minute in group I, 0.93 μl/minute in group II and 1.05 μl/minute in group III. The mean PICF procalcitonin level was 7.28 pg/mL in group I, 41.3 pg/mL in group II and 118.6 pg/mL in group III. Conclusion: Higher level of salivary and peri- implant crevicular fluid level of procalcitonin in peri- implantitis and peri- mucositis patients as compared to healthy subjects.