Abstract: It is known that, against the background of the progression of chronic hepatitis, significant changes in blood elements are occurring. The number of red blood cells, the level of hemoglobin, the color index, the content of reticulocytes, platelets and leukocytes in patients with chronic diffuse diseases of the liver are significantly lower than in people without diseases of the hepatobiliary system, and blood counts decrease as the activity of inflammation in the liver and the transformation of chronic hepatitis B increase cirrhosis of the liver. The purpose of this work is to identify the features of the hemogram in patients with cirrhosis of the liver.