Online ISSN: 2515-8260
Pop-up Announcement

Lessons from the left heart in developing novel therapeutic options for right heart failure in pulmonary arterial hypertension

Main Article Content

1Nayan Kumar Patel, 2Rekha Manjhi, 3Sudarsan Pothal, 4Narendra, 5Pravati Dutta, 6Aurobindo Behera

Abstract

In pulmonary arterial hypertension, right heart function is the most important indicator of prognosis (PAH). As we will show in this post, there are currently no medicines available that directly target the right ventricle. When analysed using the pump-function graph, a meta-analysis of clinical trials in PAH found that current PAH treatment appears to have minimal cardiac-specific effects. We investigated the clinical potential of left heart failure (LHF) therapy for PAH based on currently available data, driven by the idea that "left" and "right" heart failure may share fundamental underlying pathophysiological mechanisms

Article Details