Clinical learning is an integrated part of nursing, is extensively valuable through nursing education. The study was to identify challenges faced by nursing students in clinical. A quantitative approach was undertaken to assess the nursing students’ perception & challenges faced in the CLE in selected Nursing Colleges of Bhubaneswar. 685 samples were selected by purposive sampling technique & data was collected by Modified CLEI & MPCI. RESULT: As per the perception of nursing students 1.3% having less satisfactory perception & 73% of students having more satisfactory perception in clinical settings. The challenges are; they were unaware about the objectives (43.65%), Clinical Instructor doesn’t have time to assess students (53.13%), Students don’t stay enough time inward (57.21%), Lack of interest on the part of clinical instructor (50.21%), Lack of interest in students (53.72%), Attitude of nurses towards students is not good (49.92), Attitude of patients towards students is not good (78.67%), Unavailability of enough cases to be studied to meet objectives (64.81%), The mentors level of motivation is not good (71.23%) and Inadequate availability of clinical instructors (48.02%). Pearson’s Co-relation shows a moderately negative correlation between the nursing students perception and challenges as the r-value is -0.0188(0