ABSTRACT Contemporary shopper market has been creating as a trap of images and signs in multidisciplinary way to deal with build product pictures in the purchaser's discernment. Simiology is a propelled subjects wherein illuminated the semiotics preferably. Promoting, publicizing and correspondence are the indistinguishable, joined significant transporters in particular market – shopper social world. In this connection, Advertisements are building and deconstructing the sign and images to make affirmative picture and to present to them the fulfillment to propel to buy creations. Possible investigation of the semiotics shows that the lingo based medium and the picture based media are the crucial and the inescapable mechanism for the individual correspondence. The sign and images can be scientific classifications as intrapersonal and relational. Taking into thoughtfulness of the coverage and stout substantiation on the above said aspects in literature the current research aims at indulgent the blow of Science of Semiotic Usage on Teenagers’ Perception. At the same time, it also tries to figure out the mediating role of Semiotic Usage in the nexus between advertisements and Teenagers’ Perception. Suitable survey data collected from 150 respondents from various colleges going teenagers’ students based at Guntur and Vijayawada Cities Andhra Pradesh, India are analysed by by means of SPSS AMOS 23 through structural equation modeling. The outcome discovered a momentous direct impact of advertisements on Teenagers’ Perception. Further, it is recognized that Semiotic Usage has played noteworthy mediating role between advertisements and Teenagers’ Perception. Implications are discussed and implications are presented.