Purpose ▪ To identify the stress‑related physiological parameters of ophthalmic surgeons during complicated cataract surgeries and compare the same factors with uncomplicated routine cataract surgery and study the variations between the two groups. Method: Patients attending the Karnataka Institute of Medical Sciences ophthalmology OPD were considered for the study. The patients included in this study ranged between 45 and 80 years of age, they were grouped into two groups of 50 patients each and divided into complicated and uncomplicated cases. Group 1 included patients having cataracts corresponding to nuclear sclerosis ≤ Grade 4, posterior subcapsular cataract, and cataract with good pupillary dilatation (>7 mm) and no other ocular comorbidities. Group 2 included patients with mature, hypermature cataract, posterior polar cataract, traumatic cataract, cataract with poor pupillary dilatation (<5 mm), one‑eyed patients, pseudo‑exfoliative syndrome, patients with chronic or recurrent uveitis, floppy iris syndrome, and systemic comorbidities (cognitive disorder, Parkinson’s disease, Alzheimer’s disease, patients on tamsulosin). All patients underwent manual small incision cataract surgery with intraocular lens implantation. The outcomes measured were systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), and saturation of peripheral oxygen (SpO2). The surgeons were required to answer a set of questions to assess any external factors adding to stress during surgeries.