Wound healing is one of the challenging clinical problems, need for correct and efficient wound management is essential. The management of high energy open fractures is one of the difficult problems confronting the orthopaedic surgeons. After obtaining approval and clearance from the institutional ethical committee, the patients with open type IIIB tibia fractures admitted in Department of Orthopaedics hospital attached to BMCRI, fulfilling the inclusion criteria were enrolled for the study after obtaining informed consent. Demographic data, history, clinical examination and details of investigation and intervention were recorded in the study proforma after admission. After assessment, patients were randomly allocated into two groups i.e. Group A (patients treated with vacuum assisted closure) and Group B (patients treated with conventional dressing). Among 20 patients treated with vacuum assisted dressings, the mean reduction in size of the wound overall is 13.05 mm and appearance of healthy granulation tissue is better compared to conventional dressing (P-0.018). 11 patients wound was closed by split skin grafting and 9 wounds were secondarly healed with Vacuum-assisted closure (VAC) treatment on comparison with 20 patients treated with conventional betadine dressings the mean reduction in size of the wound overall is 5.15 mm. 10 patients wound was closed by split skin grafting and 10 wounds were secondarly healed with conventional betadine dressings treatment without requiring a secondary procedure. There is significant decrease in reduction in size of wound and average duration with VAC.