Online ISSN: 2515-8260

THYROID PROFILE IN HYPOTHYROIDISM PREGNANT WOMEN: A PROSPECTIVE CASE CONTROL STUDY

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Priti Yadav, Jigar Katwala, Keyur Madhu, Smita Rani Pradhan

Abstract

Background: Thyroid dysfunction is the second most common endocrinological disorder seen during pregnancy. The main cause of hypothyroidism is a thyroid abnormality majorly with iodine deficiency. Thyroid hormones play a crucial role in the placental development. So, this study to assess thyroid levels in pregnant women who are hypothyroid. Methods: The study included 70 hypothyroid pregnant and 40 non-pregnant women, with institutional ethical committee approval and informed written consent obtained. The student t test was used to compare thyroid hormones. Thyroid profile was done by fully auto COBAS 6000 system analyzer. all women with TSH level>2.5 mIU/l, considered to be hypothyroid Results: A total of 140 women. Group 1 included all women with TSH levels greater than 2.5 mIU/l, who were considered hypothyroid (n=70); Group 2 included women with euthyroid status and TSH levels ranging from 0.1 to 2.5 mIU/l (n=70). Table 1 showed maternal characteristics. Graph-1 displayed the mean thyroid profile values, which included TSH, T3, and T4 levels. Conclusion: The study's findings are useful for detecting thyroid dysfunction early in pregnancy and avoiding adverse maternal and fetal outcomes.

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