Nanomaterial fabrication has been an extensive research area in the past decade, especially with managed morphologies side by side, having remarkable properties. Nowadays, naturally available substances and waste products from factories have built growing implementations in the Metal Oxide Nanoparticles (MONPs) synthesis because they can play multiple roles such as complexing agents, catalysts, capping agents, reducing agent, etc. Besides, plants, algae, fungi, yeast, virus, and bacteria are a green and safe way of creating MONPs concerning the traditional methods of using chemicals. This viewpoint includes several kinds of biogenic pathways that have been used to fabricate MONPs, the inclusion of their functions, and mechanism. This review consists of discussions of potential applications of MONPs derived from biogenic materials to store Energy, Remediation of nature, and bio-related sensors. Overall we intended to highlight the biogenic route to form transition MONPs and highlight future potentials, toxicity, and stability of MONPs.