ABSTRACT Background: Yoga asanas and pranayama can control the blood sugar in a costeffective manner, as there is no requirement of any sophisticated equipment with maximum space or fitness classes. The aim of this study to evaluate the effect of Yoga on blood sugar and body mass index (BMI) values for different time durations of Yoga training at tertiary care center. Materials & Methods: A cross sectional observational study done on 200 subjects of both the genders in the age group 20-50 years were performed in the Department of physiology and Lala Lajpat Rai Memorial (LLRM) Medical College, Meerut, U.P., India during one year period. Subjects performed asanas supervised by primary investigator, in sitting, standing and lying position for 45 minutes daily, five days a week. Each asana was performed for 3 repetitions and the end position of each repetition was hold for 30 seconds. Purak and Rechak (deep breathing) was coordinated with the different posture of every asana. Thirty seconds rest period was given between each asana. Cool down was done with Shavasana for 5 minutes. Appropriate descriptive and implemented statistics were carried out using SPSS (Statistical Package for Social Sciences) version 22.0 software. Results: Our study showed that 62% of participants were between 41-50 years among males and 92% of participants between 31-50 year’s in females. Both male and female participants showed a negative correlation between the blood sugar level and yoga performance. Also,a negative correlation existed between the BMI and their yoga performance. Positive correlation is seen between the blood sugar levels and BMI values in both genders. Conclusion: Yoga cannot cure diabetes but keeps a beneficial check on blood sugar values. Hence yoga is more of cost effective, does not need any equipment as in exercise, it can be done within four walls with adequate ventilation and long term effect of this yoga can explore the beneficial effects on glucose and other hormonal homeostasis, insulinsensitivity, it can improve cognition, and keep the body in shape with a sense of well-being.