Online ISSN: 2515-8260

A PROSPECTIVE STUDY OF SERM CALCIUM, MAGNESIUM, URIC ACID AND LIVER ENZYMES IN PREGNANCY INDUCED HYPERTENSION

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Dr.Borra Dharmendhar1 , Dr.Laxmi Chapidi2 , Dr.Ketham Veera Sudhakar3 , Dr.Kankata Jhansi Rani

Abstract

Introduction: Hypertensive disorders in pregnancy (HDP) are one of the deadly triads, along with hemorrhage and infection, and are responsible for 10.8% of maternal mortality in India. In preeclampsia and eclampsia, significant changes are seen in various biochemical parameters like uric acid and serum calcium. Hyperuricemia due to oxidative stress is associated with deleterious effects on endothelial dysfunction, oxidative metabolism, platelet adhesiveness, and aggregation. Hence, elevated serum uric acid is highly predictive of increased risk of adverse maternal and fetal outcomes. Blood calcium has a relaxant effect on the blood vessels of pregnant women.

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