Background: Availability of blood and its components is becoming scarce day by day because of increasing demand due to rise in human life expectancy and the implementation of new and aggressive therapeutic methods requiring large quantities of blood and blood products; but supply is not matching with the demand. In many instances replacement donors are not available like in emergency, non-availability of eligible donors among patient attenders, thalassemia patients who require frequent blood transfusion and cannot arrange for replacement donor every time. Supply of both replacement and voluntary blood donors are increasing but still not matching with the increasing demand.