Gall stones are found in middle aged females who with higher BMI. In younger patients with gall stones, hemolytic diseases should be considered. Inpatients admitted in General Surgery Department, who underwent laparoscopic Cholecystectomy were the study subjects. All the patients were scored pre-operatively according to history, clinical examination, biochemical parameters, and sonological findings. Out of 60 patients, 44 patients had history of gall bladder disease with symptoms of which 24 patients had easy surgery and 20 had difficult surgery. Out of 60 patients, 18 patients had tenderness in right hypochondrium of which 6 patients had difficult surgery.