Emerging growth of smart devices and application of smart screens in every consumer product enable the peoples to get compulsive interaction with the touch screen. Smart devices with flexible interactive option and evaluation of data analytics and machine learning keeps the humans get addicted with the devices day and night. Even though it offers us numerous advantages over time, Studies revealed that physiological changes are more prospected due to excessive interaction with the smart devices. Nowadays, human health history is ruined by technology in the form of endless connection with such device usage for long period which causes health issues like mental stress, behavior related problems. There are many sources to address stress in our routine life. Many studies have depicted the most impacted factors in smart devices. This paper focus on detailed study depicting the impacts of smart devices human body influenced by touch screen devices highly towards sense organs. Moreover, the biggest sense organ skin that acts as a communication medium for conducting such tiny electrical signals got affected a. Evaluation of big data analytics everywhere in medical industry to keep the patient information more secure and provides statistical view of such problem globally. Healthcare analytics has been changed into digital mode to keep patient’s data most secure, less expensive, and easily accessible. Here, the problem begins with touch screen-based intervention in stress, including literature review in contrast with previous work in blood pressure and the proposed evaluation approaches.