Purpose: This meta-analysis and systematic review was conducted to highpoint the current literature and establish data relating the mortality of coronavirus disease 2019 (COVID-19) in patients with and without asthma. Search criteria: The Scopus, Embase, PubMed, medRxiv. org and Google Scholar databases were explored for studies associating the clinical results with and without asthmatic patients diagnosed with COVID-19. Mortality data were summarizing with the Mantel-Haenszel OR with 95% CI in a randomeffects model. Five retrospective studies encountered the inclusion criteria. A meta-analysis of data from 1181 asthmatic patients and 8,847 nonasthmatic patients specified that the presence of asthma had no extensive consequence on mortality rate (OR = 0.96; 95% CI 0.70–1.30; I 2 = 0%; p = 0.79). Result: Results were steady in a sensitivity analysis. A descriptive examination of other clinical outcomes selected no modification in the duration of hospitalization and the risk of intensive care unit (ICU) transfer between asthmatic and nonasthmatic patients. Conclusion: Asthma may not upsurge the mortality of COVID-19.