Background Children with asthma face multiple challenges that encompass learning how to cope with. Bronchial asthma is a public health problem in all countries irrespective of their level of development, being generally under-diagnosed and undertreated, and most asthma-related death commonly occurs in low-income and lower-middle income countries. Family management of asthmatic children is affected by several factors, primarily the parent’s knowledge and attitude toward asthma. In 2004, the highest prevalence of asthma was reported by physicians in Saudi Arabia (25%). Bronchial asthma is a serious disease since it is very common disease in Saudi Arabia, and it doesn’t only affect the individual physiologically, however it also affects the individual’s quality of life, leading to missing days from school or work, emergency hospital visits, hospitalization, and caregivers and parents’ time and effort. Consecutively, it affects the whole community, asthma, the most common chronic illness in children is responsible for more school absenteeism than any other single chronic childhood condition. Aim of the study: To assessment the level of Knowledge of parents about asthma in their children at MakahMethod: A cross-sectional study was conducted attending the primary health care centers in Makkah, Saudi Arabia. An asthma Knowledge of parents about childhood asthmawas used to measure the knowledge. During the October toNovember, 2019, participants were (200).