The locations are commonly used in orthodontic applications for the placement of miniscrew because of their ease of access, the interradicular spaces are limited by the proximity of neighboring roots. Methodology- Cone-beam computed tomography (CBCT) scans of 30 consecutively healthy patients (12 men and 18 women) who went to the Department of Orthodontics and Dentofacial Orthopaedics made up the collection. Three grouping methods were applied for these patients: they were grouped by sex (12 males and 18 females), age (15 adolescents [14.4 ± 2.8 years of age] and 15 adults [25.6 ± 2.98 years of age]), and by sex and age (6 male adolescents, 9 female adolescents, 6 male adults, and 9 female adults). Results- Since no statistical differences were detected be- tween left and right sides for palatal thickness (hard tissue, soft tissue, and hardþsoft tissues) (P ¼ .296), the left and right side measurements were combined for statistical analyses. Two-way ANOVA with repeated measures revealed that the thickness of hard tissues was significantly influenced by different coronal planes (P1, P2, M1, and M2) (P , .001), different sites away from the midpalatal suture (0 to 10 mm) (P , .001), and by their interaction (P , .001). Conclusion- Clinicians are advised to map out the most appropriate and ideal locations for palatal mini-implants.