Aim: A research with the goal of determining the antibiotic susceptibility pattern of uropathogens responsible for catheter-associated urinary tract infections (CAUTI) in a tertiary care hospital. Materials and Methods: There were a total of 300 individuals that required catheterization. During her daily rounds, the infection control nurse gathered all of the pertinent information, such as the patient's name, age, sex, the date of their catheterization, and laboratory findings. The CAUTI diagnosis was carried out in accordance with the CDC criteria that were issued in 2009. Patients of both sexes who were more than 18 years old and who had been placed on a Foley's catheter for at least 48 hours were considered for inclusion in the research. This selection criteria were used to determine who would be included in the study. Results: Out of 300 catheterized patients, 20 developed CAUTI. The overall incidence was 6.67%. Male patients were more than the female patients for catheterization. Catheterization days ranged from 2 days to 12 days. The most common uropathogens were E. coli (40%) and Klebsiella pneumoniae (40%) followed by Pseudomonas aeruginosa (10%) and Acinetobacter species (10%) from the cases of CAUTI. Imipenem was the single best antibiotic for all pathogens except Pseudomonas aeruginosa where Amikacin was the drug of choice. The Acinetobacter species also showed very high resistance to all antibiotics except Imipenem.