Background & Method: The study is conducted with an aim to study Antibiotic resistance among Uropathogenic Escherichia Coli, targeted both male and female outpatients and inpatients presenting with symptoms and signs of UTI which include dysuria, polyuria, fever, nausea, and flank pain were sampled for this study. This study is done with an aim to study Antibiotic resistance among Uropathogenic Escherichia Coli. Baseline demographic data including age, sex, level of education and risk factors such as catheterization, history of UTI, also out and in patients were also collected.