Introduction: In the new era of urbanization and westernization of lifestyle in our hour is faster. Busy lifestyle influences the adolescents in hearing music. It is one of the stress busters in the modern world. Adolescents are spending more time on music with earphone and they are unaware of the health hazards.The main aim is to determine the knowledge and practices of earphone uses among adolescents. Methodology: The quantitative approach with a non-experimental research design was adopted. The data was collected from 150 adolescents by a structured knowledge questionnaire and standardized practice questionnaire in selected +2 science college, Bhubaneswar, Odisha. Result: The study shows that 44% of students are mild addiction 55.33% of students are moderate addiction, and 0.66% of students are severe addiction for using earphones. The majority (64%) of the adolescent children had average knowledge 21.3% of the sample had poor knowledge and 14.7% of the study sample had good knowledge regarding the hazards of earphone usage. There was no significant association between Sex, Types of family, Education among adolescents with selected socio-demographic variables. Conclusion: The present study revealed that very few students who have severe level addiction and rest are the majority who have not excessively but moderately involved in addictive’s uses. Hence, some awareness should be increased among students through various programs.